Product Description
Bremelanotide (PT-141)yog ib qho hluavtaws heptapeptide analog ntawm -melanocyte-stimulating hormone ( -MSH). Raws li kev xaivmelanocortin receptor agonist, qhov kev tshawb fawb no sawv cev rau cov cuab yeej tseem ceeb rau kev kawm receptor signaling pathways. Peb siab -purityPT-141 peptide hmoovyog tsim nyob rau hauv nruj nruj tswj tej yam kev mob, muab kev soj ntsuam nrog ib tug txhim khu kev qhatshawb fawb tshuajrau kev tshawb nrhiav melanocortin system mechanisms. Qhov notshuaj intermediateyog qhov zoo tshaj plaws rau kev tshawb nrhiav biochemical siab heev thiab kev tshawb fawb receptor binding hauv kev tshawb fawb tshawb fawb.
Physicochemical Properties
| Khoom | Specification |
|---|---|
| Khoom npe | Bremelanotide (PT-141) |
| Khoom muag | Dawb kom tawm -dawb lyophilized hmoov |
| Cov mis mos molecular | C50H68N14O10 |
| Molecular hnyav | 1025.2 g / mol |
| CAS Nr | 189691-06-3 |
| Purity (HPLC) | >98% |
| Txee lub neej | 24 hli |
| Solubility | Soluble hauv dej, acetic acid daws; sparingly soluble hauv cov kuab tshuaj organic |
| Cia | Khaws ntawm -20℃hauv airtight thawv. Tiv thaiv los ntawm lub teeb thiab noo noo. |
Cov yam ntxwv tseem ceeb
Qhov no hluavtaws peptide muab cov kws tshawb fawb nrog ntau yam kev zoo rau kev tshawb nrhiav tshwj xeeb:
- Targeted Receptor Kev Koom Tes:Qhia txog kev xaiv affinity rau melanocortin receptors MC1R thiab MC4R, ua hauj lwm raws li ib tug meej pharmacological cuab yeej rau kev kawm receptor activation mechanisms thiab ligand-receptor kev sib cuam tshuam.
- Chromatographic Purity:Tshaj li 98% purity los ntawm HPLC kev tshuaj ntsuam xyuas lav qhov cuam tshuam tsawg kawg nkaus, kom ntseeg tau tias muaj kev ntseeg siab thiab muaj txiaj ntsig zoo ib yam ntawm cov kev tshawb fawb tshawb fawb.
- Lyophilization Stability:Lub freeze- cov qauv qhuav khaws cia molecular kev ncaj ncees raws li kev pom zoo cia, muab kev muaj peev xwm txuas ntxiv mus ntev - cov kev tshawb fawb lub sij hawm yam tsis muaj kev txhawj xeeb txog kev puas tsuaj.
- Methodological Flexibility:Ua ke nrog ntau hom kev tshawb fawb xws li hauv vitro binding assays, cellular teb cov kev tshawb fawb, thiab kev tshawb nrhiav kev siv tshuab hauv cov chaw soj ntsuam.
- Manufacturing Reproducibility:Ua raws li cov txheej txheem kev lees paub zoo tswj hwm cov yam ntxwv zoo tib yam peptide thoob plaws cov khoom tsim khoom, txhawb nqa kev tshawb fawb tshawb fawb thiab kev sim ua kom raug.
Cov ntawv thov tshawb fawb
Bremelanotide (PT-141) pab txhawb kev tshawb fawb txog kev tshawb fawb hauv ntau qhov kev tshawb fawb:
1. Kev tshawb fawb txog Neuropharmacology:
- Kev tshuaj xyuas ntawm melanocortin -kev kho cov kab mob neural signaling pathways
- Kev tshawb nrhiav ntshav -b hlwb barrier penetration mechanisms
- Kev tsom xam ntawm neuropeptide faib thiab metabolism
2. Receptor Pharmacology:
- Quantitative binding affinity ntsuas ntawm melanocortin receptor subtypes
- Cov qauv- qauv kev sib raug zoo ntawm peptide analogs
- Competitive binding thiab receptor activation profileing
3. Cellular Signaling Research:
- Qhov thib ob tub txib txoj kev tshawb fawb ua kom muaj zog (cAMP, calcium flux)
- Intracellular signaling cascade tsom xam
- Receptor internalization thiab recycling mechanisms
4. Kev Txhim Kho Kev Tshawb Fawb:
- Mass spectrometry reference standard for peptide quantification
- Chromatographic txoj kev txhim kho thiab validation
- Kev tswj hwm raws tu qauv tsim rau peptide-raws li kev sib txuas
Kev tshuaj xyuas ntawm Sermorelin
Cov lus nug nquag nug (FAQ)
Q: Cov kev tswj xyuas zoo li cas rau koj qhov Bremelanotide (PT-141)?
A: Each batch undergoes rigorous testing including HPLC-UV for purity verification (>98%), huab hwm coj spectrometry rau kev pom zoo ntawm cov qauv, thiab cov amino acid tsom xam rau cov kab ke validation. Daim Ntawv Pov Thawj Kev Ntsuam Xyuas Tag Nrho yog muab nrog rau txhua qhov khoom xa tuaj.
Q: Koj puas tuaj yeem muab Bremelanotide hauv ntau qhov ntau rau -cov haujlwm tshawb fawb loj?
A: Yog, peb tshwj xeeb hauv kev tsim khoom ntau thiab tuaj yeem muab ntau-kilogram kom muaj nuj nqis. Peb lub peev xwm tsim tau txhawb nqa loj - cov kev tshawb fawb loj nrog kev khaws cia zoo thiab sib xws.
Q: Dab tsi yog koj lub sij hawm ua tus thawj coj rau kev txiav txim ntau ntawm GMP-qib Bremelanotide?
A: Lub sij hawm ua tus qauv rau GMP- qib xaj ntau yog 6-8 lub lis piam tom qab kev txiav txim pom zoo. Accelerated ntau lawm xaiv muaj rau kev tshawb fawb ceev.
Q: Koj puas tuaj yeem muab cov ntaub ntawv ruaj khov thiab pom zoo cia cov xwm txheej rau ntev - khaws cia ntev?
A: Cov ntaub ntawv kev ruaj ntseg zoo muaj nyob rau hauv peb cov ntaub ntawv thev naus laus zis. Rau lub sijhawm ntev - khaws cia, peb pom zoo kom -20℃hauv cov thawv ntim nrog cov desiccant. Raws li cov xwm txheej no, cov khoom lag luam tswj kev ruaj ntseg rau 24 lub hlis.
Q: Koj qhov kev txiav txim yam tsawg kawg nkaus yog dab tsi rau kev cai synthesized Bremelanotide analogs?
A: MOQ rau kev cai analogs feem ntau yog 5 grams. Txawm li cas los xij, qhov no tuaj yeem sib txawv raws li qhov sib txawv ntawm qhov sib txawv thiab cov kev xav tau hloov kho. Thov sab laj nrog peb cov kws tshaj lij rau cov haujlwm tshwj xeeb.
OME kev pabcuam
Ntim & Shipping
Daim ntawv pov thawj
Yuav tiv tauj peb li cas?
Yog tias koj xav tau cov khoom no rau koj cov kev xav tau tshawb fawb, thov hu rau peb ntawmella.zhang@huilinbio-tech.comlos tham txog kev tsim khoomBremelanotide rau kev tshawb fawblub hom phiaj.
Tsis lees paub
Bremelanotide peptideyog npaj rau kev tshawb fawb nkaus xwb. Tsis yog rau kev kuaj mob, kho, lossis kev siv cov neeg siv khoom. Txhua qhov kev tshawb fawb yuav tsum ua raws li cov cai thiab cov txheej txheem hauv tsev.
Cim npe nrov: Bremelanotide Powder, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, ntuj, zoo, Tshuag, kev muag
