Khoom Description
Mandelic Acid Hmoovyog siab -purity, cosmetic-qib alpha-hydroxy acid (AHA) muab los ntawm iab almonds. Raws li ib tug dawb mus tawm-dawb crystalline hmoov nrog ib tug yam ntxwv faint aromatic tsw, nws yog dav muaj nuj nqis nyob rau hauv daim tawv nqaij formulations rau nwsloj molecular lojpiv rau lwm cov AHAs (glycolic, lactic acid), uas ua rau qeeb ntawm daim tawv nqaij nkag mus rau hauv lub cev thiab ua rau lub cev tsis muaj zog.softer, tsawg irritating exfoliation profile. Qhov no ua rau nws tshwj xeeb tshaj yog haum rau cov tawv nqaij rhiab heev thiab kho hyperpigmentation, pob txuv, thiab yees duab.
Cov khoom tseem ceeb Specifications
| Yam ntxwv | Specification |
|---|---|
| Khoom npe | Mandelic Acid Hmoov |
| CAS Nr | 90-64-2 |
| EINECS Number | 202-007-6 |
| Tshuaj Formula | C₈H₈O₃ |
| Molecular Luj | 152.15 g / mol |
| Specification (Purity) | Ntau dua lossis sib npaug li 98% (los ntawm HPLC) |
| Qhov tshwm sim | Dawb rau tawm -dawb, oblique flake crystalline hmoov |
| Melting Point | 119-121 degree |
| Boiling Point | 321.8℃ntawm 760 mmHg |
| Qhov ntom | 1.30 g / cm³ |
| Kev sib hloov tshwj xeeb | [ ]²⁰/D=+156.57℃(c=1, dej) –Faj seeb: Qhov no qhia txog DL- daim ntawv haiv neeg |
| Solubility | Dawb soluble hauv dej kub, ethanol, diethyl ether, thiab isopropanol; me ntsis soluble nyob rau hauv dej txias. |
| Flash Point | 162.6 hli |
| Cia | Khaws rau hauv lub thawv kaw nruj nreem nyob rau hauv qhov chaw txias, qhuav, zoo - qhov cua, tiv thaiv los ntawm lub teeb. Ntev ntev raug rau huab cua / noo / tshav kub tuaj yeem ua rau tsis muaj xim. |
| Txee lub neej | 24 lub hlis raws li kev cia khoom kom raug. |
| Ntim | 1 kg aluminium foil hnab / 25 kg fiber ntau nruas (OEM kev cai muaj). |
Nkag siab Mandelic Acid vs. DL-Mandelic Acid
Ib qho kev tsis meej pem hauv kev lag luam raw khoom yog qhov sib txawv ntawm "Mandelic Acid" thiab "DL-Mandelic Acid."
| Feature | Mandelic Acid | DL-Mandelic Acid |
|---|---|---|
| Chemical Identity | Lub compound nws tus kheej muaj xws li ob enantiomers:D-formthiabL-form. | A sib xyaw haiv neegmuaj qhov sib npaug ntawm D- thiab L-enantiomers. |
| Optical Activity | Optically nquag (xws li + lossis - kev sib hloov). | Tsis muaj kev sib hloov kho qhov muag (optically inactive). |
| CAS Nr | D-form: 611-71-2; L-form: 17199-29-0 | DL-kev sib tw: 90-64-2(the common CAS) |
| Kev ua lag luam tiag | Pure D- lossis L- cov ntawv yog kim thiab tsis tshua siv hauv kev lag luam tawv nqaij lossis tshuaj lom neeg ntau. | Tshaj 99% ntawm kev lag luam "Mandelic Acid Powder" yog daim ntawv DL-racemic. |
| Hom npe | Tsis tshua muag li "Mandelic Acid" yam tsis muaj kev tsim nyog. | Cov qauv kev lag luam; tsuas sau npe liMandelic Acidlos yogDL-Mandelic Acidsib pauv. |
Tswv yim Takeaway rau buyers:
Thaum koj yuav khoomMandelic Acid Hmoov(CAS 90-64-2) los ntawm ib lub chaw muag khoom loj, koj tau txaisDL-Mandelic Acid. Cov ntsiab lus muaj txiaj ntsig zoo sib xws hauv cov tshuaj pleev ib ce, tshuaj, thiab kev lag luam raw khoom lag luam. Peb cov khoom yog tus qauv DL-racemate nrog purity ntawm ntau dua lossis sib npaug li 98%.
Cosmetic & Pharmaceutical Benefits
1. Maj mam Exfoliation
Vim nwsloj molecular hnyav(152 vs. glycolic acid's 76), mandelic acid nkag mus rau ntawm daim tawv nqaij ntau dua thiab sib npaug. Qhov no ua rau ame me, sustained exfoliating kev uanrog tsawg stinging, liab, los yog khaus piv rau lwm yam AHAs. Zoo tagnrho rau rhiab heev, rosacea-nrawm, lossis hom tawv nqaij reactive.
2. Muaj txiaj ntsig tiv thaiv hyperpigmentation
Mandelic acid inhibits tyrosinase, enzyme tseem ceeb hauv melanin synthesis. Cov kev tshawb fawb soj ntsuam pom tias nws txo qismelasma, tom qab -inflammatory hyperpigmentation (PIH), thiabtshav ntujnrog rau kev pheej hmoo tsawg dua ntawm kev tshaj tawm - mob hyperpigmentation nyob rau hauv cov duab tsaus nti ntawm daim tawv nqaij (Fitzpatrick IV-VI).
3. Pob txuv & Sebum Tswj
Nws cov khoom keratolytic pab unclog pores thiab txo cov comedones. Tsis tas li ntawd, mandelic acid muajantibacterial kev ua haujlwmtawm tsamPropionibacterium pob txuvthiabStaphylococcus epidermidis, ua rau nws muaj txiaj ntsig zoo rau pob txuv - cov qauv tsim tsis muaj qhov hnyav ntawm benzoyl peroxide.
4. Anti-Kev laus & Collagen Stimulation
Zoo li lwm yam AHAs, mandelic acid txhawb nqa dermal remodeling los ntawm stimulating collagen thiab glycosaminoglycan synthesis, txo cov kab zoo, wrinkles, thiab txhim kho daim tawv nqaij firmness thiab hydration.
5. Muaj & Pharmaceutical Siv
- Organic Synthesis Intermediate:Siv nyob rau hauv kev tsim tshuaj, naj hoom, thiab preservatives.
- Analytical Reagent:Keeb kwm siv los ua ib qho reagent tshwj xeeb rau kev txiav txim siab gravimetric ntawmzirconium.
- Preservative thiab Antimicrobial:Muab cov tshuaj tua kab mob me me uas haum rau qee cov tshuaj pleev ib ce.
Daim ntawv thov Fields tseem ceeb
| Kev lag luam | Daim ntawv thov | Hom Concentration |
|---|---|---|
| Tshuaj pleev ib ce & Skincare | Tshuaj pleev ib ce (hauv tsev & kws tshaj lij), tshuaj tiv thaiv- cov tshuaj tiv thaiv kev laus, tshuaj kho pob txuv, pleev pleev xim, toners, tshuaj ntxuav. | 1% - 10% (tso -rau); 5% - 15% (tev, siv kev tshaj lij). |
| Kev npaj tshuaj | Pob txuv gels (ua ke nrog clindamycin, thiab lwm yam), wart removers. | 5% – 10% |
| Kev kho qhov ncauj | Muaj peev xwm muaj nyob rau hauv kev tiv thaiv -plaque mouthwash (theem tshawb fawb). | <2% |
| Tshuaj Synthesis | Intermediate rau mandelate esters, mandelic acid derivatives, thiab lwm yam tshuaj zoo. | / |
Cov txheej txheem tsim
1. Pom zoo siv qib (Skincare)
| Yam khoom | Nco ntsoov | pH ntau | Sau ntawv |
|---|---|---|---|
| Txhua hnub Toners / Serums | 1% – 5% | 3.5 – 5.0 | Neutralize ib nrab rau cov tawv nqaij rhiab heev. |
| Overnight Exfoliating Creams | 5% – 10% | 3.0 – 4.0 | Siv cov khoom xyaw soothing (panthenol, allantoin). |
| Professional Chemical Peels | 10% – 30% | 1.5 – 3.0 | Yuav tsum neutralization; cov neeg ua haujlwm raug cob qhia nkaus xwb. |
| Lub ntsej muag ntxuav / Cleansers | 2% – 5% | 4.0 – 5.5 | Yaug-tawm cov mis; kev khaus tsawg. |
2. Solubility & tuav
Solubility:Dawb soluble hauv dej kub, ethanol, thiab isopropanol. Rau txias- txheej txheem txheej txheem, ua ntej- dissolve nyob rau hauv ib tug me me ntawm cov dej sov los yog glycol (xws li, propylene glycol, glycerin) ua ntej ntxiv mus rau qhov kawg batch.
Kev ruaj ntseg: Stable in the pH range of 2.5–6.0. Avoid strong oxidizing agents and high temperatures (>80 degree) rau lub sijhawm ntev.
Kev Tiv Thaiv Discoloration:Mandelic acid tej zaum yuav daj los yog xim av thaum lub sij hawm raug rau huab cua, noo noo, los yog lub teeb. Khaws rau hauv airtight, lub teeb -cov thawv tiv taus. Ntxiv ib qho me me ntawm cov tshuaj tiv thaiv antioxidant (xws li, tocopherol, BHT) rau cov qauv kawg tuaj yeem txhim kho xim stability.
3. Mandelic Acid vs. Lwm yam AHAs
| AHA os | Molecular Luj | Kev nrawm nrawm | Irritation Potential | Zoo tshaj rau |
|---|---|---|---|---|
| Glycolic acid | 76 | Ceev ceev | Siab | Oily, tuab, tawv tawv; tob peeling. |
| Lactic Acid | 90 | Nruab nrab | Nruab nrab | Hydration + maj mam exfoliation. |
| Mandelic Acid | 152 | qeeb | Tsawg | Cov tawv nqaij rhiab heev, hyperpigmentation, pob txuv, rosacea. |
Kev nyab xeeb, ua raws li & tuav
1. Kev ruaj ntseg Profile
- Daim tawv nqaij Irritation: At concentrations below 10% and pH >3.5, mandelic acid yog suav hais tias yog ib qho me me rau nruab nrab ntawm daim tawv nqaij khaus (tsawg dua glycolic). Kev tsim kom raug (buffering, suav nrog cov tshuaj soothing) raug pom zoo.
- Sun Sensitivity:Raws li nrog rau tag nrho cov AHAs, cov khoom uas muaj mandelic acid yuav ua rau kom cov tawv nqaij rhiab heev rau UV hluav taws xob. Yuav tsum muaj daim ntawv qhia hnub ci ceeb toom hauv ntau lub khw.
- Toxicity:Tsawg qhov ncauj thiab dermal toxicity. Txawm li cas los xij, kev noj ntau ntau yuav ua rau mob plab hnyuv.
2. Txoj Cai Tswjfwm
| Thaj tsam | xwm txheej |
|---|---|
| Tebchaws Meskas | FDA- tswj raws li AHA cov khoom hauv cov tshuaj pleev ib ce; tso cai txog li 30% hauv cov kws tshaj lij thiab 10% hauv cov khoom lag luam niaj hnub (nrog pH Ntau dua lossis sib npaug rau 3.5 thiab cov ntawv sau kom zoo). |
| European Union | Tso cai nyob rau hauv cov khoom siv tshuaj pleev ib ce raws li Cosmetics Regulation (EC) No 1223/2009. Mandelic acid yog teev nyob rau hauv Annex III nrog kev txwv ntawm qhov siab tshaj plaws concentration thiab pH rau tawm - rau thiab yaug - tawm cov khoom. |
| Tuam Tshoj (NMPA) | suav nrog hauvDaim ntawv teev cov khoom siv tshuaj pleev ib ce uas twb muaj lawm. Ua raws li kev siv hauv cov khoom tu tawv nqaij nrog kev txwv concentration raws li cov qauv kev nyab xeeb. |
| Lwm Cheeb Tsam | Feem ntau txais; ib txwm txheeb xyuas cov kev cai hauv zos ua ntej qhov khoom kawg tso tawm. |
3. Kev Ntsuas Zoo
Txhua pawg ntawm peb Mandelic Acid Powder yog nruj me ntsis kuaj los ntawmHPLC (High -Kev Ua Haujlwm Liquid Chromatography)los xyuas kom meej purity Ntau dua los yog sib npaug rau 98%.
Cov lus nug nquag nug (FAQ)
Q: Dab tsi yog qhov txawv ntawm Mandelic Acid thiab DL-Mandelic Acid?
A: Hauv cov ntsiab lus kev lag luam, tsis muaj qhov sib txawv. Tshaj 99% ntawm mandelic acid hmoov muag rau cov tshuaj pleev ib ce thiab kev lag luam siv yog DL-racemic sib tov (CAS 90-64-2). Pure D- lossis L- cov ntawv tsis tshua muaj, kim, thiab tsis tas yuav tsum tau siv rau cov txheej txheem exfoliating lossis brightening daim ntawv thov. Peb cov khoom yog tus qauv DL-daim ntawv, uas ua haujlwm zoo ib yam rau txhua "mandelic acid" uas koj pom hauv cov khoom tu tawv nqaij tiav.
Q: Puas yog Mandelic Acid muaj kev nyab xeeb rau txhua hom tawv nqaij, suav nrog cov tawv nqaij tsaus?
A: Yog. Mandelic acid yog ib qho kev nyab xeeb tshaj plaws ntawm AHAs rau cov tawv nqaij tawv tawv (Fitzpatrick IV-VI) vim tias nws qeeb, maj mam nkag mus ua rau txo qis kev pheej hmoo ntawm post- mob hyperpigmentation- ib qho kev txhawj xeeb uas muaj zog AHAs zoo li glycolic acid.
Q: Kuv puas tuaj yeem siv Mandelic Acid nrog lwm cov khoom xyaw nquag (retinol, vitamin C, niacinamide)?
A: Yog, tab sis nrog ceev faj. Tsis txhob tso ncaj qha ntawm mandelic acid nrog siab -concentration retinol lossis vitamin C (L-ascorbic acid) tib lub sijhawm kom txo qis kev khaus. Hloov lawv (AM / PM) lossis siv nyob rau hauv cov txheej txheem sib cais. Niacinamide feem ntau sib xws.
Q: Kuv yuav khaws Mandelic Acid Powder li cas?
A: Khaws rau hauv qhov chaw txias, qhuav nyob rau hauv lub kaw ntom nti, lub teeb -cov ntaub ntawv pov thawj (thawj ntim lossis HDPE / iav). Tsis txhob muaj cov av noo siab thiab kub siab tshaj 30 degree. Kev khaws cia kom zoo, nws tseem nyob ruaj khov rau 24 lub hlis.
Q: Vim li cas kuv cov hmoov mandelic acid tej zaum tsis xim (tig liab los yog daj)?
A: Discoloration yog ib qho cim ntawm degradation vim raug huab cua ntev, ya raws, cua sov, los yog lub teeb. Txawm hais tias cov hmoov tsis muaj xim me ntsis tseem tuaj yeem ua tau zoo purity (kuaj ntawm HPLC), peb xav qhia tawm tsam kev siv cov khoom tsis zoo hauv cov tshuaj pleev ib ce. Nco ntsoov khaws cov ntim kom nruj tom qab qhib.
Q: Dab tsi yog qhov pom zoo pib concentration rau DIY lub ntsej muag serum?
A: Rau kev siv hauv tsev, pib nrog 2-5% mandelic acid nyob rau hauv dej -raws li cov ntshav nrog pH hloov mus rau 3.5-4.5. Ib txwm ua qhov ntsuas patch ua ntej daim ntawv thov tag nrho. Siv tshuaj pleev thaiv hnub txhua hnub thaum siv AHAs.
Ua tam sim no
Tiv tauj peb hnub no kom thov tus qauv dawb, tau txais daim ntawv pov thawj ntawm Kev Ntsuam Xyuas, lossis sib tham txog koj cov kev cai ntim khoom thiab daim ntawv lo xav tau.Peb pab neeg tau npaj los pab koj tsim cov khoom tu tawv nqaij zoo dua thiab cov khoom siv tshuaj nrog tus nqi zooMandelic Acid Hmoov.
Thov hu rau peb ntawmella.zhang@huilinbio-tech.com.
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