Dab tsi yogPentapeptide-18?
Pentapeptide-18, feem ntau hu ua Leuphasyl nyob rau hauv cov tshuaj pleev ib ce peptide kev lag luam, yog ib tug hluavtaws biomimetic neuropeptide muaj li tsib amino acids nrog rau ib theem zuj zus.Tyr-D-Ala-Gly-Ph-Leu-OH. Nws yog ib qho kev hloov kho analog ntawm endogenous neuropeptideLeu-nkephalin, nyob rau hauv qhov thib ob - txoj hauj lwm glycine yog hloov nrog D-alanine - kev hloov kho cov qauv uas ua rau muaj kev txhim kho kev tiv thaiv rau proteolytic degradation thiab txhim kho kev ruaj ntseg hauv cov qauv tshuaj pleev ib ce.
Tsim los ntawmLipotechauv Barcelona, Spain, Pentapeptide-18 tau qhia tias muaj kev nyab xeeb dua, tsis yog -invasive lwm txoj kev kho mob xws li txhaj tshuaj botulinum toxin. Nws cov txheej txheem ntawm kev ua yog tshwm sim los ntawm enkephalins - endogenous neuropeptides uas txo qis kev sib kis ntawm neural. Los ntawm kev khi rau enkephalin (opioid) receptors ntawm neuronal daim nyias nyias, Pentapeptide-18 txo acetylcholine tso tawm los ntawm G-protein-mediated calcium channel inhibition, yog li hloov qhov kev siv ntawm lub ntsej muag cov leeg micro-contractions uas ua rau kev nthuav tawm wrinkle tsim.
Peb Pentapeptide-18 Powder yog tsim los ntawm kev tshaj lijKhoom -Phase Peptide Synthesis (SPPS)nrog kev tswj kom zoo. Qhov tshwm sim yog ib qho tsis tu ncua ntshiab, ruaj khov, thiab cov hmoov bioactive uas ua tau raws li cov kev cai nruj nruj ntawm cov npe khoom noj khoom haus thoob ntiaj teb.
Ntsiab nta & qhov zoo
- Neuro-Modulating Mechanism- Mimics endogenous enkephalins kom txo tau cov acetylcholine tso tawm thiab ua kom cov leeg nqaij contraction - "Botox{0}}zoo li" cov nyhuv yam tsis muaj kev txhaj tshuaj
- Siab Purity- Muaj nyob hauv Ntau dua lossis sib npaug rau 98% thiab Ntau dua lossis sib npaug rau 95% purity (HPLC + MS)
- Txhim khu kev ruaj ntseg- D-Ala² hloov pauv muab kev tiv thaiv zoo tshaj plaws rau enzymatic degradation vs. natural enkephalins
- Dej Solubility zoo heev- Soluble hauv dej, glycols, thiab DMSO; yooj yim rau muab tso rau hauv aqueous formulations
- Broad pH stability- ruaj khov ntawm pH 4.0 - 7.5 (zoo pH 5.0 - 7.0)
- Synergistic Potential- Thaum ua ke nrog Acetyl Hexapeptide-8 (Argireline), ua tiav47% synergistic wrinkle- txo qhov tob
- Txoj Cai Ua Raws Cai- NMPA- pom zoo tsawg dua lossis sib npaug li 1.86% hauv cov khoom tiav; EU-ua raws
- Clean & Synthetic- 100% hluavtaws; tsis muaj tsiaj- muab cov khoom xyaw; haum rau vegan thiab huv huv formulations
- Ntau hom ntawv- Muaj li lyophilized hmoov los yog kua kua
Technical Specifications (Tswj - Ntau dua lossis sib npaug rau 98% Qib)
| Parameter | Specification | Txoj Kev Xeem |
|---|---|---|
| Khoom npe | Pentapeptide-18 (Leuphasyl) | - |
| CAS Nr | 64963-01-5 | - |
| INCI npe | Pentapeptide-18 | - |
| Synonyms | Leuphasyl; TIAB SA 374895 | - |
| Molecular Formula | C₂₉H₃₉N₅O₇ | - |
| Molecular Luj | 569.6 - 569.7 g / mol | - |
| Ib ntus | H-Tyr-D-Ala-Gly-Ph-Leu-OH | - |
| Qhov tshwm sim | Dawb kom tawm -dawb lyophilized hmoov | Pom kev |
| Kev Ntsuas (Purity) | Ntau dua lossis sib npaug li 98.0% (HPLC) | HPLC |
| Purity (Ntau dua lossis sib npaug rau 95% qib) | Ntau dua lossis sib npaug li 95.0% (HPLC + MS) | HPLC + MS |
| Counter-Ion | TFA ntsev (Acetate / HCl pauv muaj) | - |
| Solubility | Soluble hauv dej, glycols, DMSO | - |
| pH Stability Range | 4.0 – 7.5 | - |
| Pom zoo cia | 2℃- 8℃(luv-lub sijhawm); -20℃(ntev ntev) | - |
| Hnyav Hlau | Ua raws li cov qauv tshuaj pleev ib ce | ICP-MS |
| Tag nrho cov phaj suav | Tsawg dua lossis sib npaug li 1,000 CFU / g | USP<61> |
| Poov & Pwm | Tsawg dua lossis sib npaug li 100 CFU / g | USP<2021> |
| E. coli | Tsis zoo / 10g | USP<2022> |
| Salmonella | Tsis zoo / 10g | USP<2022> |
Specifications yog rau siv. Thov thov COA tam sim no rau batch- cov ntaub ntawv tshwj xeeb.
Pentapeptide 18 Cov txiaj ntsig ntawm daim tawv nqaij tseem ceeb
Pentapeptide-18 (leuphasyl peptide) yog ib qho kev tshawb fawb pom tau tias muaj cov neuropeptide uas muaj pov thawj los tiv thaiv kev ua kom tawv nqaij. Nov yog cov txiaj ntsig tseem ceeb txhawb los ntawm kev tshawb fawb:
Txo Cov Lus Qhia Wrinkles - "Botox-Zoo" nyhuv yam tsis muaj kev txhaj tshuaj
- Pentapeptide-18 ua raws li aneuromodulator, mimicking ntuj enkephalins kom txo tau neuronal excitability thiab tom qab cov leeg nqaij contraction.
- Los ntawm kev khi rau enkephalin (opioid) receptors thiab activating Gi/o-protein signaling, nws inhibits voltage-gated calcium channels thiab txo cov acetylcholine tso tawm.
- Qhov no txo qhov kev siv ntawm lub ntsej muag cov leeg micro-kev cog lus uas ua rau kev nthuav tawm wrinkles - tsis muaj kev pheej hmoo lossis cuam tshuam ntawm kev txhaj tshuaj.
- Thaum ua ke nrog Acetyl Hexapeptide-8 (Argireline), nws ua tiav a47% synergistic wrinkle- txo qhov tob.
Targets Dynamic Wrinkles - Hauv pliaj, Crow's Feet & Perioral Kab
- Tshwj xeeb tsim los nyobkab lustshwm sim los ntawm kev rov ua lub ntsej muag.
- Siv tau rau hauv pliaj plhis, crow's ko taw (qhov muag cheeb tsam), thiab perioral (di ncauj) kab.
- Zoo tagnrho rau"Botox{0}}alternative"daim tawv nqaij formulations.
Distinct Mechanism - Ua tiav lwm yam Neuropeptides
- Pentapeptide-18's mechanism yogcomplementary thiab txawvlos ntawm Argireline:
- Argirelineblocks SNARE complex sib dhos (pre-synaptic)
- Leuphasylactivates opioid receptors kom txo tau acetylcholine tso tawm ntawm G-protein-mediated calcium channel inhibition (ib qho sib txawv ua ntej-synaptic mechanism)
- Qhov no mechanical complementarity justifies lawvua kenyob rau hauv advanced anti-wrinkle formulations.
Txhim kho daim tawv nqaij Hydration, Elasticity & Texture
- Tshaj li qhov txo qis, Pentapeptide-18 ib txhij txhim khodaim tawv nqaij hydration, elasticity, thiab kev ntxhib los mos.
- Pab txhawb rau tag nrho cov tawv nqaij rejuvenation thiab ib tug hluas nkauj tsos.
Clinically Proven & Regulatory Pom Zoo
- NMPA- pom zoo tsawg dua lossis sib npaug li 1.86% hauv cov khoom tiav.
- EU-ua raws li Txoj Cai 1223/2009.
- Pom zoo raws li cov khoom siv tshuaj pleev ib ce hauv Nyij Pooj (JP-CI 2020-038).
- Txhawb los ntawm cov phooj ywg- tshuaj xyuas kev tshawb fawb thiab kev lag luam cov ntawv dawb.
Haum rau Sensitive Skin & Clean Beauty
- Synthetic, tsis yog -invasive, thiab zoo- zam.
- Tsis muaj tsiaj- muab cov khoom xyaw - haum rau vegan thiab huv cov qauv kev zoo nkauj.
- Qhov zoo tshaj plaws rau cov neeg siv khoom nrhiav kev tiv thaiv zoo - cov kev daws teeb meem kev laus yam tsis muaj kev pheej hmoo ntawm cov tshuaj txhaj.
Pentapeptide-18 Daim Ntawv Thov
- Anti-Wrinkle Serums- Cov tshuaj tiv thaiv kab mob rau kev qhia kab, hauv pliaj wrinkles, thiab crow's ko taw.
- Qhov muag Contour Creams- Yooj yim tab sis zoo formulations rau qhov muag muag qhov muag.
- "Botox-Alternative" Skincare– Premium formulations positioned as non-invasive alternatives to injectables.
- Hnub & Hmo Moisturizers- Kev tiv thaiv txhua hnub thiab kho me me ntawm kab lus.
- Lub ntsej muag, caj dab & tes tu- Kev tiv thaiv -kev kho mob rau ntau qhov chaw.
- Kev tu plaub hau- Nourishing thiab ntxiv zog formulations.
- Xim Cosmetic (Makeup)- Kev tiv thaiv - cov txiaj ntsig kev laus hauv cov hauv paus thiab primers.
- Kev kho daim di ncauj- Cov khoom lag luam rau cov kab perioral.
- Cosmeceutical & Aesthetic Post-Kev saib xyuas- Tsev-cov khoom kho mob tom qab kev kho mob tshaj lij.
Tuam txhab Taw Qhia
Xi'an Huilin Bio-tech Co., Ltd. Peb muab cov tshuaj ntsuab extracts, standardized extracts, thiab txiv hmab txiv ntoo / zaub hmoov. Kev mob siab rau kev ua tau zoo thiab kev tsim kho tshiab, peb pab cov neeg siv khoom thoob ntiaj teb hauv cov khoom siv tshuaj, khoom noj khoom haus, thiab tshuaj pleev ib ce, ua rau tib neeg noj qab haus huv.Nyem qhov no kom paub ntau ntxiv.
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Daim ntawv pov thawj
FAQ
Q: Qhov txawv ntawm Pentapeptide-18 thiab Argireline yog dab tsi?
A: Ob leeg yog neuromodulating peptides nrog cov txheej txheem ntxiv:
Argirelineblocks SNARE complex sib dhos los tiv thaiv kev tso tawm neurotransmitter.
Leuphasylactivates opioid receptors kom txo tau acetylcholine tso tawm ntawm G-protein-mediated calcium channel inhibition.
Ua ke ob qho tib si ua tiav a47% synergistic wrinkle-depth txo.
Q: Cov khoom puas haum rau vegans thiab neeg tsis noj nqaij?
A: Yog. Peb Pentapeptide-18 yog 100% hluavtaws, tsim los ntawm Solid-Phase Peptide Synthesis (SPPS). Tsis siv cov khoom xyaw tsiaj los ntawm cov tsiaj.
Q: Nws puas muaj allergens?
A: Peb Pentapeptide-18 Hmoov yog dawb los ntawm cov tshuaj tsis haum loj xws li gluten, mis nyuj, soy, qe, ntses, plhaub ntses, txiv laum huab xeeb, thiab ntoo txiv ntoo. Cov lus tshaj tawm Allergen muaj nyob rau ntawm kev thov.
Q: Dab tsi yog qhov pom zoo siv qib?
A: Kev pom zoo siv nws txawv ntawm daim ntawv thov:
- Lub ntsej muag lub ntsej muag: 0.01% - 0.03%
- Moisturizers: 0.005% - 0.02%
- Cov khoom pov tseg: 0.005% - 0.05%
- Qhov dav dav: 0.01% - 0.5%
- Qhov siab tshaj plaws NMPA-pom zoo concentration: Tsawg dua lossis sib npaug rau 1.86%
Q: Nyob rau theem twg yuav tsum Pentapeptide-18 ntxiv rau cov qauv?
A: Ntxiv rau lub sijhawm txias (hauv qab 45 degree) ntawm theem kawg ntawm kev tsim los khaws peptide bioactivity.
Q: Cov khoom xyaw twg ua haujlwm zoo nrog Pentapeptide-18?
A: Pentapeptide-18 ua haujlwm sib koom ua ke nrog:
- Acetyl Hexapeptide-8 (Argireline)- 47% synergistic wrinkle-depth txo
- Vitamin C derivatives- Txhim khu kev tiv thaiv antioxidant
- Lwm yam neuromodulating peptides- Cov txheej txheem ntxiv rau cov txheej txheem tiv thaiv-wrinkle siab heev
- Palmitoyl Tripeptide-1- Txhim kho daim tawv nqaij elasticity txhim kho
Q: Puas yog Pentapeptide-18 tshav kub-ruaj khov?
A: Pentapeptide-18 yuav tsum tau ntxiv thaum lub sij hawm txias txias (hauv qab 45 degree) kom tsis txhob thermal degradation. Lyophilized hmoov yuav tsum muab cia rau hauv tub yees (2℃- 8 degree).
Yuav tiv tauj peb li cas?
Rau cov lus nug ntau, qauv, lossis kev cai tshwj xeeb, thov hu rau peb pab pawg muag khoom. Peb tos ntsoov yuav koom tes nrog koj kom ua tau zooPentapeptide-18 hmoov(Leuphasyl) uas ua tau raws li koj cov cai.
Yog tias koj xav tau cov khoom no, thov hu rau peb ntawmella.zhang@huilinbio-tech.com.
Cim npe nrov: Pentapeptide-18 Powder (Leuphasyl), Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, ntuj, zoo, Tshuag, kev muag
