Taw qhia
Chasteberry Extractyog muab tau los ntawm qhuav mature txiv hmab txiv ntoo ntawmVitex agnus-castusL., tsob ntoo Mediterranean belongs rau tsev neeg Lamiaceae (yav tas los Verbenaceae). Kev lig kev cai hu ua "monk's pepper" vim nws keeb kwm siv hauv cov zej zog monastic, chasteberry tau siv ntau pua xyoo los pab txhawb cov poj niam kev laus kev noj qab haus huv thiab kev sib npaug hormonal.
Cov txiv hmab txiv ntoo muaj ib tug nplua nuj array ntawm bioactive compounds nrog rauiridoid glycosides(agnuside, aucubin),flavonoids(casticin, orientin, isovitexin, vitexin), thiab cov roj yam tseem ceeb. Ntawm cov no,agnusidethiabcasticinraug lees paub tias yog cov cim tseem ceeb sib txuas rau kev tsim qauv zoo.
Kev tshawb fawb niaj hnub no tau lees paub qhov kev siv tshuaj chasteberry, nrog rau ntau qhov kev sim tshuaj ntsuam xyuas pom tias nws muaj txiaj ntsig zoo hauv kev txo cov tsos mob ntawm tus mob premenstrual syndrome (PMS) thiab txhawb nqa hormonal equilibrium.
Peb Chasteberry Extract Powder yog tsim los ntawm ethanol / dej extraction tom qab tshuaj tsuag - ziab, kom ntseeg tau tias cov khoom xa tuaj zoo ib yam thiab batch - rau -batch reproducibility. Peb muab ntau yam kev qhia tshwj xeeb- suav nrogratio-raws li extracts(4:1–20:1) thiabcov ntsiab lus -raws li specifications(Agnuside 0.5–2%; Vitexin 5%; Casticin 0.3–0.5%; Tag Nrho Flavonoids)- kom ua tau raws li kev thov ntau yam thoob plaws nutraceutical, zaub mov, thiab tshuaj pleev ib ce industries.
Cov ntaub ntawv technical
| Parameter | Specification / Cov ntaub ntawv |
|---|---|
| Lub npe Latin | Vitex agnus-castus L. |
| Nroj tsuag siv | Qhuav txiv hmab txiv ntoo |
| Qhov tshwm sim | Xim av- daj rau xim av zoo hmoov |
| tsw & saj | Yam ntxwv, me ntsis iab |
| Particle Loj | 80 mesh (D90 < 250 μm) |
| Solubility | Ib nrab soluble hauv dej; soluble nyob rau hauv ethanol |
| Poob rau ziab | Tsawg dua lossis sib npaug li 5.0% |
| Tshauv Ntsiab Lus | Tsawg dua lossis sib npaug li 5.0% |
| pH (1% tov) | 4.5–6.5 |
| Kev ceev ceev | 0.40-0.65 g / ml |
| Active Markers | Agnuside (0.5-2% HPLC), Vitexin (5% UV), Casticin (0.3-0.5% HPLC), Tag Nrho Flavonoids |
| Tus neeg nqa khoom | Maltodextrin (yeem, tsis muaj cov cab kuj) |
| Hnyav Hlau | Pb Tsawg dua lossis sib npaug li 2 ppm; Tsawg dua lossis sib npaug li 1 ppm; Cd Tsawg dua lossis sib npaug li 1 ppm; Hg Tsawg dua lossis sib npaug li 0.1 ppm |
| Microbiological | TPC Tsawg dua lossis sib npaug li 1,000 cfu / g; Poov & Pwm Tsawg dua lossis sib npaug li 100 cfu / g;E. coli & Salmonella: tsis zoo |
| Txee lub neej | 24 hli |
| Cia | Txias, qhuav, tiv thaiv lub teeb; rov kho sai |
| Kev tswj hwm xwm txheej | Tso cai ua zaub mov thiab cov khoom xyaw ntxiv hauv kev lag luam loj (USA, EU, Tuam Tshoj) |
Cov txiaj ntsig
Vitex Agnus-Castus extract muaj ntau yam txiaj ntsig kev noj qab haus huv, txhawb nqa los ntawm kev tshawb fawb soj ntsuam thiab siv ib txwm siv:
- Kev them nyiaj yug Hormonal Balance- Pab tswj lub cev kev coj khaub ncaws thiab txhawb kev sib npaug ntawm cov tshuaj hormonal. Cov kev tshawb fawb soj ntsuam tau pom tias chasteberry extract normalizes ob qho tib si kev coj khaub ncaws thiab qib ntawm prolactin thiab progesterone cov tshuaj hormones.
- Premenstrual Syndrome (PMS) Relief- Kev tshuaj ntsuam meta-kev soj ntsuam ntawm ob-dig muag randomized tswj kev sim tau lees paub tias kev npaj Vitex agnus-castus muaj txiaj ntsig zoo los txo cov tsos mob PMS, nrog rau cov poj niam noj VAC yog2.57 lub sij hawm ntau duakom pom cov tsos mob tshem tawm piv rau cov placebo. Ib qho kev tshawb fawb randomised, tshuaj placebo-tswj (n=170) pom tau tias muaj kev txhim kho tseem ceeb hauv kev chim siab, hloov mus rau hauv lub siab, npau taws, mob taub hau, thiab lub mis puv (P<0.001), with a responder rate of 52% for active treatment vs. 24% for placebo.
- Kev them nyiaj yug Premenstrual Dysphoric Disorder (PMDD).- Kev sim tshuaj ntsuam xyuas tau pom tias Vitex agnus-castus extract tau zoo rau kev kho PMDD, nrog qee qhov kev tshawb fawb qhia qhov sib npaug rau fluoxetine.
- Cyclical Mastalgia (mob mis) nyem- Ob qhov muag tsis pom kev, cov kev tshawb fawb placebo tswj tau pom tias Vitex agnus-castus extract txo qis qhov mob ntawm lub mis thiab rhiab heev.
- Polycystic Ovary Syndrome (PCOS) Kev them nyiaj yug- Ib qho randomized, ob-dig muag tswj kev sim tshuaj ntsuam xyuas (2026) tshawb xyuas qhov ua tau zoo ntawm cov qauv Vitex agnus-castus extract hauv kev tswj hwm PCOS cov yam ntxwv, suav nrog oxidative stress markers, lipid profile, thiab insulin tsis kam. Cov kev tshawb fawb ntxiv tau soj ntsuam nws cov teebmeem ntawm cov cim inflammatory hauv cov poj niam nrog PCOS.
- Anti-Inflammatory Activity- Agnuside nthuav qhia kev xaiv COX-2 inhibition, ua rau txo qhov mob thiab cuam tshuam tsis zoo.
- Kev noj qab haus huv ntawm daim tawv nqaij- Siv rau hauv cov khoom tu tawv nqaij kom soothing thiab sib npaug.
- Ntau yam Formulation- Muaj nyob rau hauv ntau qhov sib piv (4: 1-20: 1) thiab cov ntsiab lus tshwj xeeb (Agnuside 0.5-2%; Vitexin 5%; Casticin 0.3-0.5%) kom haum cov khoom sib txawv.
Specifications & Applications Guide
| Specification | Concentration / Cov ntsiab lus | Pom zoo daim ntawv thov | Cov ntsiab lus tseem ceeb |
|---|---|---|---|
| Piv txwv 4: 1 - 10: 1 | Tsawg-medium concentration | Cov khoom noj khoom haus Standard, capsules, ntsiav tshuaj | Me me concentration; dav phytochemical khaws cia; raug nqi |
| Piv txwv 10:1–20:1 | Nruab nrab-siab concentration | High-potency ntxiv, dej haus ua haujlwm | Siab concentration; txo cov koob tshuaj |
| Agnuside 0.5% | HPLC txheem | Standardized tshuaj, tshuaj ntsiav, ntsiav tshuaj | Kev lag luam hauv paus specification; USP siv |
| Agnuside 1% - 2% | HPLC txheem | Cov khoom noj tshwj xeeb, cov tshuaj muaj zog heev | Cov ntsiab lus agnuside siab dua rau kev txhim kho bioactivity |
| Vitexin 5% | UV/HPLC | Standardized tshuaj, khoom noj khoom haus | Cov cim tseem ceeb flavonoid; kawm tau zoo bioactivity |
| Casticin yog 0.3% - 0.5% | HPLC | High-purity formulations, kev tshawb fawb tshuaj | Tseem ceeb flavonoid; suav hais tias yog ib qho tseem ceeb active constituent |
| Tag nrho Flavonoids | UV (kev cai qib) | Antioxidant formulations, khoom noj qab haus huv | Broad flavonoid profile rau kev ua haujlwm |
| Kev cai | Customizable | Cov qauv tsim tshwj xeeb | Muaj nyob ntawm qhov kev thov; hloov tau specifications |
Cov lus nug nquag nug (FAQ)
Q: Puas yog chasteberry extract muaj kev nyab xeeb rau kev siv mus ntev?
A: Yog. Cov kev tshawb fawb soj ntsuam tau pom tias chasteberry extract tau txais txiaj ntsig zoo nrog kev nyab xeeb zoo. Hauv 3-hli randomized tswj kev sim, tsuas yog cov xwm txheej tsis zoo me me tau tshaj tawm (plaub hauv pawg neeg nquag, peb hauv pawg placebo), tsis muaj ib qho uas ua rau tsis muaj kev kho mob ntxiv.
Q: Dab tsi yog qhov pom zoo noj txhua hnub ntawm chasteberry extract?
A: Cov koob tshuaj pom zoo sib txawv raws li kev qhia tshwj xeeb thiab daim ntawv thov npaj. Rau cov qauv kev rho tawm, cov khoom noj khoom haus zoo ib yam li ntawm 150-400 mg / hnub. Rau Agnuside 0.5% standardized extract, ib ntsiav tshuaj txhua hnub feem ntau siv. Peb pom zoo kom sab laj nrog tus kws kho mob tshwj xeeb rau kev qhia tshwj xeeb rau daim ntawv thov.
Q: Yuav ua li cas chasteberry extract ua hauj lwm rau hormonal tshuav?
A: Chasteberry extract ua rau D₂ dopamine receptors nyob rau hauv lub hypothalamus, inhibiting ntau prolactin secretion. Los ntawm kev txo cov qib prolactin, nws pab kho qhov sib npaug ntawm cov tshuaj estrogen thiab progesterone, uas feem ntau cuam tshuam rau PMS thiab kev coj khaub ncaws tsis zoo. Agnuside thiab lwm cov tebchaw kuj muaj cov haujlwm zoo li estrogen.
Q: Puas yog chasteberry extract haum rau siv thaum cev xeeb tub?
A: Chasteberry extract tsis pom zoo thaum cev xeeb tub lossis pub niam mis. Vim nws txoj kev ua hormonal, nws yuav tsum tau zam thaum lub sijhawm no tshwj tsis yog tshwj xeeb qhia los ntawm kws kho mob.
Q: Puas yog chasteberry extract cuam tshuam nrog cov tshuaj?
A: Chasteberry extract tuaj yeem cuam tshuam nrog cov tshuaj dopamine ntsig txog (nrog rau cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv kab mob Parkinson) vim nws txoj haujlwm dopaminergic. Nws kuj tseem tuaj yeem cuam tshuam nrog cov tshuaj tiv thaiv hormonal thiab kev kho tshuaj hormone hloov. Cov neeg mob noj cov tshuaj no yuav tsum sab laj nrog lawv tus kws kho mob ua ntej siv.
Q: Puas yog chasteberry extract muaj lub zog saj?
A: Yog. Chasteberry extract muaj cov yam ntxwv me ntsis iab saj. Bitterness tuaj yeem sib txawv ntawm ntau txawm nyob rau tib lub hom phiaj yog tias qhov sib txawv ntawm qhov sib txawv. Rau cov kev siv saj-sensitive xws li gummies thiab dej haus, tsw-masking tshuab yuav ua hauj lwm.
Q: Dab tsi yog qhov txawv ntawm qhov sib piv specifications thiab cov ntsiab lus specifications?
A: Piv txwv specifications (piv txwv li, 10: 1, 20: 1) qhia qhov sib piv ntawm cov txiv hmab txiv ntoo nyoos mus rau qhov kawg extract hmoov. Cov ntsiab lus tshwj xeeb (piv txwv li, Agnuside 0.5%, Vitexin 5%) qhia cov qauv feem pua ntawm cov cim tshwj xeeb, ua kom muaj zog zoo ib yam tsis hais txog cov khoom siv raw variation.
Rau kev nug, hais lus, lossis cov qauv thov, thov hu rau:sales@huilinbio-tech.com
1. Schellenberg R. Kev kho mob rau cov kab mob premenstrual nrog agnus castus txiv hmab txiv ntoo extract: yav tom ntej, randomised, placebo tswj kev kawm.BMJ. 2001; 322(7279):134-137. doi: 10.1136/bmj.322.7279.134. PIB: 111595688.Qhov tseem ceeb nrhiav:Agnus castus extract tau txhim kho PMS cov tsos mob (P<0.001) with a responder rate of 52% vs. 24% for placebo.
Txuas: https://pubmed.ncbi.nlm.nih.gov/11159568/
2. Csupor D, et al. Vitex agnus-castus nyob rau hauv premenstrual syndrome: Ib qho meta- tsom xam ntawm ob- dig muag randomized tswj kev sim.Complement Ther Med. 2019 Nov. PMID: 31780016.Qhov tseem ceeb nrhiav:Cov poj niam noj VAC yog 2.57 npaug ntau dua yuav ntsib PMS cov tsos mob tshem tawm piv rau cov placebo.
Txuas: https://pubmed.ncbi.nlm.nih.gov/31780016/
3. Pillarisetti P, et al. Kev txheeb xyuas thiab tus cwj pwm ntawm agnuside, lub ntuj proangiogenic me me molecule.Eur J Med Chem. 2018; 160:193-206. doi:10.1016/j.ejmech.2018.10.009. PIB: 30340142.Qhov tseem ceeb nrhiav:Agnuside khi VEGFR2 nrog muaj zog affinity; nce HUVEC proliferation (EC₅₀=1.376 ug/mL).
Txuas: https://pubmed.ncbi.nlm.nih.gov/30340142/
4. Suksamrarn A, Kumpun S, Kirtikara K, Yingyongnarongkul B, Suksamrarn S. Iridoids nrog rau kev tiv thaiv -inflammatory kev ua los ntawmVitex peduncularis. Planta Med. 2002 Lub Ib Hlis; 68(1:72-3. doi: 10.1055/s-2002-20048. PIB: 11842334.
Txuas: https://pubmed.ncbi.nlm.nih.gov/11842334/
5. Hu Y, Hou TT, Zhang QY, Xin HL, Zheng HC, Rahman K, Qin LP. Kev ntsuam xyuas ntawm cov kev ua estrogenic ntawm cov khoom hauv cov txiv hmab txiv ntoo ntawmVitex rotundifoliaL. rau kev kho mob ntawm premenstrual syndrome.J Pharm Pharmacol. 2007 Sep; 59(9): 1307-12. doi: 10.1211/jpp.59.9.0016. PIB: 17883902.
Txuas: https://pubmed.ncbi.nlm.nih.gov/17883902/
6. Hatami A, et al. Cov nyhuv ntawm Vitex Agnus-Castus cog rau qee qhov cim ntawm Oxidative Stress, Lipid Profile thiab Insulin Resistance nyob rau hauv cov poj niam uas muaj Polycystic Ovary Syndrome: Ib qho Randomized, Ob npaug -Qhov muag tsis pom kev soj ntsuam kuaj sim.JBRA Assist Reprod. 2026; 30(1:70-78. doi: 10.5935/1518-0557.20250165. PIB: 41428718.
Txuas: https://pubmed.ncbi.nlm.nih.gov/41428718/
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