Palmitoyl Pentapeptide -4

Khoom Taw Qhia

Palmitoyl pentapeptide -4yog ib qho me me molecular polypeptide tsim los ntawm kev sib txuas collagen Ⅰ fragments nrog Palmitic Acid los ntawm amide daim ntawv cog lus, thiab nws cov peptide sequence yog Pal-Lys-Thr-Thr-Lys-Ser-OH (hu ua Pal-KTTKS luv luv, Pal hais txog palmitoyl , Lys hais txog lysine, Thr hais txog threonine thiab Ser yog hais txog serine).
Palmitoyl pentapeptide -4(Pal-KTTKS) tuaj yeem txhawb kev loj hlob ntawm collagen, hyaluronic acid (hyaluronic acid) thiab elastic fibers (Pal-KTTKS nkag mus rau hauv daim tawv nqaij thiab hydrolyzed rau hauv alkyl chains thiab KTTKS los ntawm aminopeptidase hauv daim tawv nqaij, thiab KTTKS tso tawm upregulates epidermal kev loj hlob yam tseem ceeb TGF-, uas nkoos fibroblasts mus transcribe ntau collagen), ua rau kom cov tawv nqaij noo noo cov ntsiab lus, thiab ua rau kom cov tawv nqaij tuab. Yog tias palmitoyl pentapeptide -4 ntxiv rau hauv kab lis kev cai tais ntawm fibroblasts, lub peev xwm synthesis ntawm collagen ⅰ, ⅲ, ⅳ thiab fibronectin tuaj yeem txhim kho.

Cov ntaub ntawv yooj yim

Lub luag haujlwm ntawm palmitoyl pentapeptide -4

Palmitoyl pentapeptide -4, raws li ib qho ntawm cov teeb liab peptides ntxov tshaj plaws siv hauv cov khoom tu tawv nqaij, muaj cov nyhuv tiv thaiv kev laus, uas tuaj yeem txhim kho cov tawv nqaij roughness, txo cov kab zoo, txo qhov tob thiab qhov chaw ntawm wrinkles. , thiab lwm yam, thiab muaj cov yam ntxwv ntawm me me thiab tsis khaus. Muaj ntau ntau yam kev tshawb fawb thiab cov ntaub ntawv los ua pov thawj nws cov txiaj ntsig.
1. Palmitoyl pentapeptide -4 tuaj yeem nkag mus rau lub dermis kom nce collagen, thiab thim rov qab cov txheej txheem ntawm daim tawv nqaij laus los ntawm kev tsim kho ntawm sab hauv tawm.
2. Palmitoyl Pentapeptide -4 tiag tiag yog C-terminal fragment ntawm collagen I, uas muaj cov nyhuv zoo ib yam li laser phais.
3. Txhawb kev loj hlob ntawm collagen, elastic fiber ntau thiab hyaluronic acid, txhim kho cov ntsiab lus ntawm cov dej thiab cov dej xauv ntawm daim tawv nqaij, ua kom cov tawv nqaij tuab thiab txo cov kab zoo.
4. tuaj yeem ua kom cov nyhuv nqus.

Lub hauv paus ntsiab lus thiab mechanism ntawm palmitoyl pentapeptide -4

Palmitoyl pentapeptide -4 tuaj yeem kho thiab rov tsim kho extracellular matrix thiab epidermis-dermis hlws ris (DEJ) los ntawm kev txhawb nqa cov khoom ntawm extracellular matrix elastin, fibronectin thiab glycosaminoglycan collagen (tshwj xeeb yog hom I, III thiab IV collagen), yog li ua tiav kev laus. nyhuv. Elastin, fibronectin thiab collagen ua rau daim tawv nqaij ruaj khov thiab tiv thaiv wrinkles. Lwm cov matrices extracellular tswj cov microenvironment ntawm cov ntaub so ntswg thiab hlwb, ncua kev laus ntawm tes thiab tswj cov tawv nqaij noo.
Cov qauv ntawm palmitoyl pentapeptide -4 collagen muaj feem xyuam rau cov precursor ntawm hom I collagen, uas yog ib feem ntawm collagen qauv thiab tsuas yog nce hom I thiab hom III collagen nyob rau hauv cov ntaub so ntswg los ntawm biosynthesis.

Txoj kev sib cais ntawm palmitoyl pentapeptide -4

Ib txoj hauv kev rau kev sib cais palmitoyl pentapeptide 4 belongs rau kev ua haujlwm ntawm kev sib cais polypeptide, thiab tshwj xeeb suav nrog cov kauj ruam hauv qab no: 1) muab cov hmoov nplej palmitoyl pentapeptide 4 hauv dichloromethane / methanol tov dej tov rau microwave pretreatment thiab lim; 2) sib cais thiab purification los ntawm gel permeation chromatography; 3) ob zaug thim rov qab-theem kev ua haujlwm siab ua kua chromatography sib cais thiab purification; Thiab 4) khov kom qhuav kom tau cov high-purity palmitoyl pentapeptide 4. Los ntawm txoj kev, cov crude palmitoyl pentapeptide 4 tau los ntawm solid-thesis synthesis yog sib cais thiab purified, thiab kev sib cais ceev yog siab, rhiab heev, thiab kev daws teeb meem. muaj zog; feem ntau cov tshuaj tiv thaiv kab mob, cov kuab tshuaj organic thiab cov zoo li hauv cov peptide crude tuaj yeem raug tshem tawm kom tau txais high-purity palmitoyl pentapeptide 4, thiab kev sib cais thiab purification efficiency siab.

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Peb Daim Ntawv Pov Thawj

Cov ntaub ntawv tiv tauj

Thov hu rau peb ntawmella.zhang@huilinbio-tech.com ib.

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• Peb ua raws li tag nrho cov qauv kev lag luam thiab cov cai tswj xyuas kom muaj kev nyab xeeb thiab zoo ntawm peb cov khoom.
• Peb hais kom innovation thiab kev kawm los txhawb txoj kev hloov pauv thiab txhim kho kev lag luam.
• Peb yog lub Hoobkas nyob hauv Suav teb, muab cov khoom zooPalmitoyl pentapeptide -4cov khoom thiab cov kev pabcuam tshaj lij. Cov tuam txhab ua raws li "kev ncaj ncees, kev mob siab rau, kev tsim kho tshiab thiab kev loj hlob" lub tswv yim, txhua tus neeg ua haujlwm sib koom ua ib qho.
• Peb muab qhov tseem ceeb rau cov neeg siv khoom tawm tswv yim thiab siv nws los txhim kho peb cov khoom thiab cov kev pabcuam tsis tu ncua.
• Peb lub Hoobkas tau cog lus los muab cov khoom zoo. Peb tau txais cov qauv kev tswj xyuas nruj kom ntseeg tau tias cov khoom siv purity thiab kev nyab xeeb ntawm cov khoom. Peb txais cov cuab yeej tsim khoom thiab cov cuab yeej siv los ua kom muaj kev ruaj ntseg thiab sib xws ntawm cov khoom.
• Peb cov khoom tau raug soj ntsuam nruj me ntsis thiab kuaj xyuas, thiab ua tau raws li cov qauv kev noj qab haus huv thoob ntiaj teb.
• Peb muaj ib pab neeg tshawb fawb txog kev tshawb fawb thiab kev loj hlob ntawm Palmitoyl pentapeptide -4. Lawv koom tes nrog ntau lub tsev kawm tshawb fawb thiab tsev kawm qib siab los tsim kho tshiab thiab txhim kho tas li kom lawv cov khoom sib tw hauv kev ua lag luam. Peb them sai sai rau qhov kev tshawb fawb tshawb fawb tshiab thiab cov qauv kev lag luam los xyuas kom meej qhov zoo thiab cov txiaj ntsig ntawm cov khoom.
• Peb muab cov kev pabcuam customized, thiab kho cov ntim, specifications thiab formula raws li qhov xav tau ntawm cov neeg siv khoom. Peb tuaj yeem muab cov kev daws teeb meem ntawm tus kheej thiab ua haujlwm nrog cov neeg siv khoom kom ntseeg tau tias peb cov khoom ua tau raws li lawv cov kev xav tau thiab cov kev xav tau.
• Peb muaj lub koob npe nrov thiab lub koob npe nrov. Peb raug coj los ntawm cov neeg siv khoom txaus siab, ua raws li lub hauv paus ntsiab lus ntawm kev tswj hwm kev ncaj ncees thiab kev pabcuam. Peb pab neeg ib txwm saib xyuas cov neeg siv khoom nrog tus kws tshaj lij, ua haujlwm zoo thiab tus cwj pwm zoo thiab teb lawv cov lus nug thiab xav tau raws sijhawm.

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