Cov txiaj ntsig ntawm paeoniflorin extract

Khoom taw qhia

Paeoniflorin extract hmoovyog tshuaj ntsuab extract hmoov, Moutan cortex, Suav tshuaj tshuaj npe. Dried cag bark rau peony ntawm Ranunculaceae. Ua nyob rau hauv Anhui, Sichuan, Henan, Shandong thiab lwm qhov chaw. iab, xin, me ntsis txias, lub plawv, siab, lub raum meridian, nrog rau cov cua kub cua txias, ntshav ncig, tshem tawm tsis muaj cua sov thiab lwm yam teebmeem. Moutan thiab moutanol tsis muaj tshuaj lom.

Me me deciduous perennial shrub, 1 mus rau 1.5 m siab. Hypertrophy ntawm rhizome. Cov ceg yog luv thiab tawv. Nplooj hloov, feem ntau 2 mus rau 3 compound; stalk ntev 6 ~ 10 cm; Cov nplooj ntawv ovate los yog dav ovate, cov nplooj ntawv dav dav feem ntau yog 3-lobed, lateral leaflets kuj palmately 3-lobed, tsaus ntsuab saum toj no, glabrous. Me ntsis dawb hauv qab, sparsely bearing ntev plaub hau dawb ntawm midrib. Paj nyob ib leeg ntawm ceg kawg, loj; Sepals 5, imbricate, ntsuab; Paj 5 los yog feem ntau, cov cultivars dav dav, feem ntau ob petals, zoo variation, feem ntau obovate, muaj qhov sib txawv nyob rau sab saum toj, sawv, liab, ntshav, dawb; Stamens ntau, filaments liab, anthers daj; Pistils 2-5, ntsuab, densely luv, style luv, stigma nplooj zoo li; Disk khob-shaped. Cov txiv hmab txiv ntoo yog 2 mus rau 5 lub hauv paus ntawm aggregate, oval, ntsuab, npog nrog cov plaub hau luv luv. Flowering los ntawm lub Tsib Hlis mus rau Lub Xya Hli. Txiv hmab txiv ntoo lub sij hawm Lub Xya hli ntuj mus rau Lub yim hli ntuj. Loj hlob nyob rau hauv tshav ntuj thiab fertile av, feem ntau nyob rau hauv lub vaj. Tshaj tawm hauv Hebei, Henan, Shandong, Sichuan, Shaanxi, Gansu thiab lwm qhov chaw.

Kev npaj ntawm paeoniflorin extract

Raw khoom npaj: tshiab Paeonia lactiflora rhizome yog xaiv raws li raw khoom, thiab nws yog ntxuav kom tshem tawm cov av thiab impurities ntawm qhov chaw.
Txiav thiab sib tsoo: txiav cov ntxuav Paeonia lactiflora rhizome rau hauv me me los yog nplua daim, thiaj li tso tawm cov khoom siv tau zoo. Tom qab ntawd, cov hauv paus hniav ntawm Paeonia lactiflora yog muab tso rau hauv ib lub grinder thiab hauv av rau hauv hmoov.
Extraction: sib tov Paeonia lactiflora rhizome hmoov nrog cov kuab tshuaj tsim nyog (xws li ethanol, dej, thiab lwm yam) los tsim cov extract. Cov txheej txheem sib txawv tuaj yeem siv tau, xws li soaking, reflux lossis ultrasonic-pab extraction. Lub sij hawm rho tawm thiab qhov kub thiab txias yuav tsum tau txiav txim siab raws li qhov kev sim tshwj xeeb.
Lim thiab concentration: lim cov extract los ntawm lim ntawv los yog daim nyias nyias kom tshem tawm cov khib nyiab. Cov filtrate tau muaj paeoniflorin thiab lwm cov khoom xyaw nquag. Tom qab ntawd, lub filtrate yog concentrated los ntawm ib tug concentrator los yog ib tug low-temperature concentrator, thiab cov kuab tshuaj yog evaporated, tawm hauv cov concentrated paeoniflorin extract.
Crystallization thiab purification: purity ntawm paeoniflorin tuaj yeem txhim kho los ntawm crystallization lossis ntxiv kev sib cais thiab kev ua kom huv. Cov kev siv feem ntau suav nrog kev ua kom txias crystallization, hnyav crystallization lossis cov txheej txheem chromatographic.
Kev ziab thiab kev soj ntsuam zoo: Thaum kawg, ziab cov paeoniflorin purified extract kom tshem tawm cov residual hnyav. Nyob rau tib lub sijhawm, txoj kev tshawb nrhiav kom zoo, xws li kev ua haujlwm siab ua kua chromatography (HPLC) thiab ultraviolet spectroscopy (UV), tuaj yeem siv los ntsuas qhov zoo ntawm cov extract.

Dawb peony extract cov txiaj ntsig

1. Cov teebmeem ntawm cov hlab plawv: Moutan tuaj yeem ua rau cov ntshav coronary txaus, txo cov hlab plawv thiab txo cov hlab ntsha sab laug hauv cov tshuaj loog hauv siab. Nws muaj kev tiv thaiv tseem ceeb ntawm kev sim myocardial ischemia, thiab kav ntev, thiab txo qis myocardial oxygen noj. Sodium moutanol sulfonate tuaj yeem tsis tsuas yog inhibit calcium uptake, tab sis kuj tseem inhibit 45Ca uptake thiab membrane SA cov ntsiab lus hauv calcium abnormality cardiomyocytes, uas yog nyob ntawm koob tshuaj. Lwm tus qauv ntawm prey-induced atherosclerosis,

2. Anti-inflammatory nyhuv: Dan daim tawv nqaij dej decoction kab pheeb ces kaum carageen kua nplaum edema, adjuvant mob caj dab thiab Arthus cov tshuaj tiv thaiv los ntawm ntau yam inflammatory teb inhibition, qhov no es inhibit o permeability thiab txwv tsis pub PGE2 biosynthesis, cortex moutan tsis tuaj yeem suppress residual adrenal compensatory hyperplasia. , yog tsis pom tseeb cuam tshuam rau cov metabolism hauv adrenal vitamin C, Cov txiaj ntsig no qhia tias nws tsis muaj cortisone zoo li los yog corticotropin zoo li cov teebmeem, uas yog, nws cov teebmeem tiv thaiv tsis yog nyob ntawm pituitary adrenal system.

3. Paeoniflorin extract hmoovmuaj cov nyhuv Antibacterial: Hauv kev sim hauv vitro qhia tau hais tias cortex moutan decoction ntawm bacillus subtilis, e. coli, salmonella typhi, paratyphoid coli, proteus, pseudomonas aeruginosa, staphylococcus aureus, hemolytic streptococcus, pneumococcus, vibrio cholera, thiab lwm yam muaj zog antibacterial kev ua si, peony nplooj decoction rau dysentery bacusacillus, tseem ceeb antibacterial nyhuv, cov khoom xyaw zoo ntawm gallic acid. Kev sim nrog qaib embryos tau pom tias

4.. Anticoagulant nyhuv: Hauv vitro kuaj ntawm tib neeg platelets pom tias ob qho tib si Moutan aqueous extract thiab paeoniflorol tuaj yeem inhibit thromboxane A2 ntau lawm los ntawm platelet arachidonic acid, thiab tom qab ntawd inhibit platelet aggregation, uas yog tshwm sim los ntawm inhibiting cov tshuaj tiv thaiv cyclooxygenase los ntawm arachidonic acid rau prostatic. H2. Cov methanol extract ntawm Moutan tuaj yeem cuam tshuam kev sim thrombus induced los ntawm endotoxin. Cov txiaj ntsig tau pom tias phenol, benzoyl paeoniflorin thiab benzoyl paeoniflorin tuaj yeem inhibit platelet aggregation, thaum phenol, paeoniflorin, thiab paeoniflorin tuaj yeem inhibit opsonin. Benzoyl paeoniflorin muaj cov nyhuv ntawm kev thaiv kev ua haujlwm ntawm fibrin lysogen thiab anti-fibrin lysozyme. Oxy paeoniflorin, benzoyl oxy paeoniflorin, thiab benzoyl paeoniflorin muaj cov nyhuv stabilizing ntawm cov cell liab, yog li inhibiting thrombosis. Paeoniflorin tuaj yeem inhibit platelet aggregation tshwm sim los ntawm ADP lossis collagen los ntawm kev txhaj tshuaj intraperitoneal lossis hauv vitro.

5. Qhov cuam tshuam rau lub cev tiv thaiv kab mob: nas nas gastric cortex moutan, raws li, thiab tau paeoniflorin, paeoniflorin, benzoyl oxide paeoniflorin, tuaj yeem txhawb kev txhaj tshuaj ntawm cov pa roj carbon monoxide hauv cov ntshav tshem tawm, txawm tias cov haujlwm ntawm mononuclear macrophage system hauv lub xeev qis. Kuj tseem muaj kev txhawb nqa, kev tshuaj xyuas microscopic pom Kupfer hlwb hauv daim siab thiab tus po nyob rau hauv lub zog ntawm phagocyte. Paeoniflorin thiab oxY paeoniflorin tuaj yeem txhim kho phagocytic kev ua haujlwm ntawm nas peritoneal macrophages rau emulsion hauv vitro. Kev txhaj tshuaj intraperitoneal ntawm cov kua dej pelagic tuaj yeem ua rau muaj qhov ntau ntxiv tom qab hemolysis hauv tus po ntawm nas. Paeonol intraperitoneally txhaj rau hauv nas 25mg / kg rau 6 hnub tuaj yeem ua rau qhov hnyav hnyav ntxiv, thiab tuaj yeem tiv thaiv qhov txo qis ntawm thymus hnyav los ntawm cortisone thiab cyclophosphamide. Nws tuaj yeem pom los ntawm saum toj no tias moutan tuaj yeem txhim kho kev lom zem thiab kev tiv thaiv ntawm tes.

6. Kev cuam tshuam ntawm lipid metabolism: Paeonol, paeonol, thiab paeoniflorin tuaj yeem cuam tshuam cov lipolysis ntawm lipid induced los ntawm epinephrine. Cov dej extract ntawm Pelagic cortex tuaj yeem ua rau cov piam thaj nce ntxiv rau adipogenesis hauv adipocytes, thiab pom tseeb tias nce qabzib rau adipogenesis vim yog insulin.

Cov yam ntxwv ntawm paeoniflorin extract

Ntuj qhov chaw: Paeoniflorin extract yog ib tug natural herbal compound muab rho tawm los ntawm rhizome ntawm Paeonia lactiflora, thiab tsis muaj hluavtaws los yog artificially ntxiv tshuaj. Nws yog dav siv nyob rau hauv tsoos suav tshuaj thiab cov khoom kho mob.
Multifunctional: Paeoniflorin extract muaj ntau yam kev ua ub no, suav nrog kev tiv thaiv kab mob, tiv thaiv oxidation, immunomodulation, tiv thaiv qog thiab lwm yam. Qhov no ua rau nws muaj peev xwm siv dav hauv kev kho ntau yam kab mob thiab txhawb kev noj qab haus huv.
Kev nyab xeeb: Paeoniflorin extract feem ntau suav hais tias muaj kev nyab xeeb thiab tsis muaj tshuaj lom thiab muaj kev phiv. Txawm li cas los xij, nws tseem yuav tsum tau siv kom raug raws li cov kws kho mob lossis cov kws tshaj lij, tshwj xeeb tshaj yog tias koj muaj qee yam kab mob lossis noj lwm yam tshuaj.
Antioxidant nyhuv: Paeoniflorin extract yog nplua nuj nyob rau hauv antioxidants, uas muaj peev xwm neutralize dawb radicals, qeeb oxidative kev puas tsuaj ntawm hlwb thiab tiv thaiv cov txheej txheem laus. Qhov no ua rau nws siv dav hauv kev tu tawv nqaij thiab cov khoom tiv thaiv kev laus.
Zoo bioavailability: Paeoniflorin extract muaj bioavailability zoo thiab tuaj yeem nqus tau zoo thiab siv los ntawm lub cev. Qhov no ua rau nws muaj txiaj ntsig zoo hauv kev siv tshuaj kho mob.

Cov teb twg tuaj yeem siv paeoniflorin extract?

Tsoos suav tshuaj teb: Paeoniflorin extract yog ib qho tseem ceeb ntawm cov tshuaj suav tshuaj, uas yog siv dav hauv cov tshuaj suav tshuaj. Nws yog feem ntau siv los kho cov kab mob inflammatory, kab mob gynecological thiab kab mob siab, xws li Chuanxiong tshuaj yej regulating meridians thiab Siwu decoction regulating qi thiab ntshav.
Cov khoom siv kho mob tshuaj ntsuab: Paeoniflorin extract feem ntau yog siv los ua tshuaj ntsuab kho mob cov khoom, uas muaj lub luag haujlwm ntawm kev tswj lub cev tsis muaj zog, tiv thaiv oxidation, tiv thaiv kab mob thiab txhawb kev mob plawv. Nws tuaj yeem siv los ua cov khoom kho mob lossis cov khoom noj khoom haus rau tib neeg los txhim kho lawv txoj kev noj qab haus huv thiab tiv thaiv kab mob.
Cov khoom siv tu tawv nqaij: Paeoniflorin extract feem ntau ntxiv rau cov tshuaj pleev ib ce thiab cov khoom tu tawv nqaij vim nws cov tshuaj tiv thaiv antioxidant thiab tiv thaiv kev laus. Nws tuaj yeem pab cov tawv nqaij kom cov hluas, moist thiab elastic.
Kev tshawb fawb txog kev kho mob thiab kev loj hlob: Paeoniflorin extract, raws li ib tug natural compound, muaj ntau yam biological kev ua ub no, yog li nws muaj peev xwm thov nqi nyob rau hauv kev tshawb fawb kev kho mob. Cov kws tshawb fawb tseem tab tom tshawb nrhiav thiab tsim nws daim ntawv thov hauv kev tiv thaiv qog, tiv thaiv kab mob thiab tiv thaiv kab mob.

Yuav tiv tauj peb li cas?

Peb yog ib lub tuam txhab nrog ntau xyoo ntawm kev muag khoom nyob rau hauv cov nroj tsuag extract kev lag luam. Tom qab xyoo ntawm kev ua haujlwm, peb muaj ntau yam khoom lag luam, xws li txiv hmab txiv ntoo thiab zaub hmoov, tshuaj pleev ib ce, ntsiav tshuaj khoom qab zib thiab lwm yam khoom, thiab peb yog cov khoom siv raw khoom. Tam sim no, peb lub tuam txhab muagpaeoniflorin extract hmoov nyob rau hauv tej yam uas tsis muaj nqi, uas yog dav siv nyob rau hauv cov khoom kho mob, tshuaj, tshuaj pleev ib ce thiab lwm yam teb. Cov uas xav ua cov khoom kho mob tuaj yeem yuav cov khoom siv raw no. Nyob rau tib lub sijhawm, txij li peb cov khoom muag ncaj qha los ntawm cov chaw tsim khoom, qhov zoo yog lav. Koj tuaj yeem yuav nrog kev ntseeg siab.

Yog tias koj xav yuav lossis txaus siab rau nws, koj tuaj yeem mus rau lub vev xaib thoob ntiaj teb lossis xa email rau peb tus email ua haujlwmella.zhang@huilinbio-tech.com ib. Peb yuav teb rau koj sai li sai tau thaum koj pom cov lus. Tsis tas li ntawd, koj tuaj yeem tuaj xyuas qhov chaw offline, peb lub tuam txhab nyob hauv Fengze Science Park, Block B, 170 Yanta District West Street, Xi 'an, Shaanxi Province, Chav 706, txais tos koj tuaj txog.