Yog tias koj tau saib xyuas lub ntiaj teb ntawm kev ua neej ntev, lub hlwb noj qab haus huv, lossis kev tawm dag zog, koj yuav hnov txogNAD+. Thiab yog hais tias koj tau saib mus rau hauv yuav ua li cas boost nws, tej zaum koj tau tuaj hlaNicotinamide Riboside Chloride Hmoov- feem ntau huNRlos yogNR-Cl.
Tab sis dab tsi yog qhov no ntxiv, thiab vim li cas coob tus neeg ntxiv nws rau lawv txoj haujlwm niaj hnub? Cov lus qhia no suav nrog txhua yam koj xav paub: Nicotinamide Riboside Chloride yog dab tsi, nws ua haujlwm li cas, nws cov txiaj ntsig tseem ceeb, kev pom zoo ntau npaum li cas, muaj peev xwm tshwm sim, thiab nws piv rau lwm yam NAD + precursors, xws li NMN.
Nicotinamide Riboside Chloride (NR-Cl) yog dab tsi?
Nicotinamide Riboside Chlorideyog ib daim ntawv ntsev ntawm nicotinamide riboside, uas yog ib tug tswv cuab ntawm tsev neeg vitamin B3. Nws yog ib qho pyridine -nucleoside daim ntawv ntawm vitamin B3 thiab ua haujlwm raws li qhov ncauj qhov ncauj ua ntej rau nicotinamide adenine dinucleotide (NAD+).
Hauv cov ntsiab lus yooj yim: NR-Cl yog ib qho molecule uas koj lub cev tau yooj yim hloov mus rau hauv NAD+ - ib qho tseem ceeb coenzyme pom nyob rau hauv txhua lub cell uas muaj zog koj cov metabolism, kho DNA, thiab ua kom koj lub hlwb ua haujlwm zoo.
Dab tsi ua rau NR-Cl tshwj xeeb?
Thaum niacin thiab nicotinamide kuj yog cov vitamin B3 cov ntaub ntawv uas tuaj yeem nce NAD +, NR yog metabolized rau hauv NAD + hauv cov kauj ruam tsawg dua. Qhov no txhais tau tias nws muaj txiaj ntsig zoo ntawm kev txhawb nqa NAD + qib. Daim ntawv chloride ntsev (NR-Cl) tshwj xeeb tshaj yog muaj nuj nqis rau nws cov dej solubility thiab stability piv rau cov dawb- hauv paus daim ntawv.
NR yog thawj zaug tau txheeb xyuas tias yog cov khoom noj hauv mis nyuj thiab tom qab ntawd pom tias yog lub zog NAD + ua ntej. Tam sim no nws yog tsim los siv rau hauv cov khoom noj khoom haus thiab tau txais Kev Pom Zoo Raws Li Kev Nyab Xeeb (GRAS).
Nicotinamide Riboside Chloride ua haujlwm li cas?
NAD+(nicotinamide adenine dinucleotide) yog qhov tseem ceeb rau lub neej. Nws plays ob lub luag haujlwm tseem ceeb hauv koj lub cev
- Kev tsim hluav taws xob: NAD + ua raws li coenzyme rau redox cov tshuaj tiv thaiv, nqa cov electrons los ntawm ib qho tshuaj tiv thaiv mus rau lwm qhov rau roj cellular zog.
- Cell signaling: NAD + yog substrate rau enzymes nyiamsirtuins(SIRT1 thiab SIRT3) thiab poly (ADP-}ribose) polymerases, uas koom nrog hauv DNA kho, mob, thiab kev laus.
Txawm li cas los xij, NAD + qib ib txwm poob qis nrog hnub nyoog. NAD + qib qis tuaj yeem ua rau txo qis zog, qeeb metabolism, thiab ua rau muaj hnub nyoog ntau dua - cuam tshuam txog kev noj qab haus huv.
Thaum koj noj Nicotinamide Riboside Chloride Powder, koj lub cev hloov nws mus rau hauv nicotinamide, uas tom qab ntawd hloov mus rau NAD+. Qhov no yuav pab nce qib NAD+ tsawg. Qhov tseeb, kev sim tshuaj ntsuam xyuas tau pom tias noj 100, 300, thiab 1000 mg ntawm NR koob tshuaj -nyob ntawm cov ntshav tag nrho NAD + los ntawm 22%, 51%, thiab 142% hauv ob lub lis piam xwb. Cov kev nce ntxiv tau khaws cia thoob plaws hauv 8 lub lis piam txoj kev tshawb fawb.
Cov txiaj ntsig tseem ceeb ntawm Nicotinamide Riboside Chloride
1. Cellular Energy thiab Metabolism Support
Los ntawm kev txhawb nqa NAD + qib,Nicotinamide Riboside Chloridetxhawb nqa kev ua haujlwm mitochondrial, uas yog qhov tseem ceeb rau kev tsim lub zog hauv cov hlwb. Nws txhim kho oxidative metabolism thiab muaj kev tiv thaiv cov metabolic irregularities tshwm sim los ntawm ib tug siab - noj cov rog. Nws tseem ua lub luag haujlwm hauv kev zom zaub mov kom zoo thiab nqus cov protein thiab rog.
2. Noj qab nyob zoo laus thiab kav ntev
NAD + ua haujlwmsirtuins- enzymes uas tshwm sim los txhim kho lub neej thiab kev noj qab haus huv tag nrho hauv cov tsiaj. Los ntawm kev nce qib NAD +, NR txhawb nqa cov txheej txheem kho cellular uas poob qis nrog hnub nyoog. Nws yog ib qho tseem ceeb muaj nyob rau hauv cov tshuaj uas tsom mus rau lub neej ntev thiab noj qab nyob zoo aging.
3. Kev txawj ntse thiab lub hlwb noj qab haus huv
NR tab tom kawm txog nws cov txiaj ntsig zoo hauvAlzheimer tus kab mobthiab lwm yam mob neurodegenerative. NAD + ua lub luag haujlwm tseem ceeb hauv kev noj qab haus huv ntawm hlwb hlwb, thiab cov kws tshawb fawb tab tom tshawb xyuas seb NAD + precursors zoo li NR tuaj yeem txhawb kev txawj ntse thiab tiv thaiv lub hnub nyoog - cuam tshuam txog kev poob qis.
4. Mob plawv
NR tuaj yeem pab txhawbmob plawvlos ntawm kev txhawb nqa cov hlab ntsha noj qab haus huv thiab pab tswj cov ntshav siab. Nws kuj tau qhia txog cov txiaj ntsig ntawm cov hlab plawv, suav nrog cov ntshav - qab zib - txo cov teebmeem.
5. Kev ua tau zoo thiab rov ua haujlwm
Los ntawm kev txhawb nqa mitochondrial muaj nuj nqi,Nicotinamide Riboside Chloridetuaj yeem txhim khokev ua tau zoothiabkev ua siab ntev. Nws pab txhawb kev tsim cov cellular zog, uas tuaj yeem txo qhov qaug zog thiab txhim kho lub zog.
6. Kev noj qab haus huv ntawm daim tawv nqaij
NR kuj tseem siv rau hauv daim ntawv thov kev tu tawv nqaij. Nws pab txhawb NAD + synthesis, uas txhawb kev kho cov tawv nqaij ntawm tes thiab tuaj yeem pab tiv thaiv cov tawv nqaij.
Nicotinamide Riboside Chloride vs NMN: Qhov txawv yog dab tsi?
Ob NR thiab NMN yog NAD + precursors, tab sis lawv ua hauj lwm me ntsis txawv. Thaum NMN yog ib kauj ruam ze rau NAD + hauv txoj kev sib txuas, NR hloov mus rau NMN ua ntej dhau los ua NAD+. Qee qhov kev tshawb fawb qhia tias NR yuav ruaj khov thiab zoo dua nqus qhov ncauj. Ob leeg ua tau zoo ntawm kev nce qib NAD +, thiab kev xaiv feem ntau los ntawm tus neeg nyiam thiab cov khoom muaj.
Pom zoo noj
Txoj caikoob tshuajNicotinamide Riboside Chloride nyob ntawm koj lub hom phiaj thiab kam rau ua:
| Lub hom phiaj | Pom zoo noj |
|---|---|
| Kev noj qab haus huv dav dav thiab NAD + kev saib xyuas | 100-300 mg ib hnub twg |
| Kev txhawb nqa siab dua / tiv thaiv -aging | 300-1,000 mg ib hnub twg |
| Cov poj niam cev xeeb tub los yog lactating | Txog li 230 mg ib hnub twg (nyob rau hauv kev saib xyuas kev kho mob) |
Kev sim tshuaj xyuas tau siv koob tshuaj 100, 300, thiab 1,000 mg, tag nrho cov no tau nce qib NAD + ntau ntxiv. European Food Safety Authority (EFSA) tau txiav txim siab tias NR-Cl muaj kev nyab xeeb rau cov neeg laus noj qab haus huv ntawm koob tshuaj txog 300 mg / hnub, thiab kev noj ntau txog 230 mg / hnub yog kev nyab xeeb rau cov poj niam cev xeeb tub thiab lactating.
Thaum coj nws:Nicotinamide Riboside Chloride tuaj yeem noj txhua lub sijhawm ntawm hnub. Qee tus neeg nyiam noj nws thaum sawv ntxov lossis ua ntej kev tawm dag zog. Nws tuaj yeem sib xyaw nrog dej, kua txiv hmab txiv ntoo, lossis ntxiv rau cov tshuaj ntsiav.
Nco tseg:Qee qhov kev pab ntxiv pom zoo kom noj 500 mg ib hnub twg. Ib txwm pib nrog cov koob tshuaj qis dua txhawm rau ntsuas koj lub siab ntev thiab sab laj nrog koj tus kws kho mob rau cov lus qhia tus kheej.
Cov teebmeem thiab kev nyab xeeb
Puas yog Nicotinamide Riboside Chloride muaj kev nyab xeeb?
Yog lawm.EFSA tau xaus lus tias NR-Cl muaj kev nyab xeeb rau kev siv hauv cov khoom noj ntxiv rau cov neeg laus noj qab haus huv ntawm koob tshuaj txog 300 mg / hnub. Cov txheej txheem tsim khoom, muaj pes tsawg leeg, thiab ruaj khov ntawm NR-Cl tsis ua rau muaj kev txhawj xeeb txog kev nyab xeeb.
Cov teebmeem tshwm sim
Thaum noj ntawm cov koob tshuaj pom zoo, cov kev mob tshwm sim feem ntau yog me me thiab tuaj yeem suav nrog:
- Ntshai
- Bloating lossis mob plab
- Teeb meem ntawm daim tawv nqaijxws li khaus lossis tawm hws
Cov kev mob tshwm sim no feem ntau zoo ib yam li cov pom nrog niacin.
Clinical Trial Safety Data
Hauv kev sim tshuaj 8 lub lis piam, muajtsis muaj ntawv ceeb toom ntawm dej ntwsthiabtsis muaj qhov sib txawv tseem ceeb hauv cov xwm txheej tsis zoonruab nrab ntawm NR thiab pawg placebo. NR kuj tseem tsis tau nce LDL cov roj cholesterol lossis dysregulate ib -carbon metabolism.
Kev ceev faj tshwj xeeb
- Cev xeeb tub thiab pub niam mis: NR-Cl tuaj yeem muaj kev nyab xeeb ntawm koob tshuaj txog 230 mg / hnub, tab sis nrog koj tus kws kho mob tham ua ntej siv.
- Cov tshuaj ntshav siab: NR tuaj yeem txo cov ntshav siab. Noj nws nrog cov tshuaj antihypertensive yuav ua rau cov ntshav siab poob qis heev.
- General: Nco ntsoov nrog tus kws kho mob tham ua ntej pib cov tshuaj ntxiv, tshwj xeeb tshaj yog tias koj noj tshuaj lossis muaj mob hauv qab.
Cov lus nug nquag
Q: Nicotinamide Riboside Chloride Hmoov siv rau dab tsi?
A: Nws yog siv los ua kev noj haus ntxiv los txhawb lub zog ntawm tes, kev laus noj qab haus huv, kev paub txog kev ua haujlwm, kev mob plawv, thiab kev tawm dag zog los ntawm kev txhawb nqa NAD + qib.
Q: Puas yog Nicotinamide Riboside Chloride tib yam li niacin?
A: Tsis yog. Ob leeg yog cov qauv ntawm cov vitamin B3, tab sis lawv yog cov sib txuas sib txawv. NR yog qhov ua tau zoo dua NAD + ua ntej thiab tsis feem ntau ua rau cov dej ntws tawm nrog niacin.
Q: Nws siv sijhawm ntev npaum li cas rau Nicotinamide Riboside Chloride ua haujlwm?
A: Cov kev tshawb fawb soj ntsuam pom tau hais tias NAD + qib tuaj yeem nce ntxiv hauv 2 lub lis piam ntawm kev noj tshuaj ntxiv.
Q: Puas yog Nicotinamide Riboside Chloride muaj kev nyab xeeb rau kev siv sijhawm ntev -?
A: Yog. Kev sim tshuaj ntsuam xyuas tau pom tias NR muaj kev nyab xeeb tshaj li 8 lub lis piam ntawm kev siv tas li, thiab EFSA tau soj ntsuam nws txoj kev nyab xeeb rau kev siv cov khoom noj.
Q: Kuv puas tuaj yeem noj Nicotinamide Riboside Chloride nrog lwm cov tshuaj?
A: Yog. Nws feem ntau ua ke nrog lwm cov khoom xyaw xws li resveratrol, pterostilbene, lossis NMN. Txawm li cas los xij, nrog koj tus kws kho mob tham ua ntej sib xyaw nrog cov tshuaj.
Q: Puas yog Nicotinamide Riboside Chloride vegan?
A: Yog. NR-Cl yog synthetically tsim thiab haum rau vegan thiab neeg tsis noj nqaij noj.
Kab hauv qab
Nicotinamide Riboside Chloride Hmoov(NR-Cl) yog ib qho bioavailable, ruaj khov daim ntawv ntawm vitamin B3 uas yog ib tug muaj zog precursor rau NAD+ - cov coenzyme tseem ceeb uas ua rau koj lub hlwb, kho DNA, thiab txhawb kev laus laus.
Nrog kev txhawb nqa kev tshawb fawb muaj zog, muaj txiaj ntsig zoo rau kev nyab xeeb, thiab ua kom pom qhov ua tau zoo hauv kev nce qib NAD +, NR-Cl yog ib qho kev cog lus zoo tshaj plaws rau cov neeg uas nrhiav kev txhawb nqa lawv cov metabolism, kev txawj ntse, kev noj qab haus huv ntawm lub plawv, thiab tag nrho lub zog.
Txawm hais tias koj yog tus tsim qauv tsim cov khoom lag luam mus ntev, tus tswv lag luam tab tom nrhiav kom nthuav koj txoj kev noj qab haus huv, lossis ib tus neeg nrhiav kev txhim kho koj txoj kev noj qab haus huv, siab - zooNicotinamide Riboside Chloride Hmoovmuaj kev tshawb fawb -cov kev daws teeb meem uas koj tuaj yeem ntseeg tau.