Dab tsi yog cov haujlwm ntawm ceramide hmoov hauv tshuaj thiab zaub mov?

Ib qho yooj yim qhia txog ceramides

Ceramide hmoovFeem ntau pom muaj nyob rau hauv cov nroj tsuag xws li mov, pob kws, taum pauv, thiab konjac. Nws yog cov khoom lag luam nyob rau hauv daim ntawv ntawm cov hmoov dawb, uas muaj peev xwm ua kom cov hlwb, uas tuaj yeem txhawb cov cell metabolism, thiab txhawb kev tsim cov keratin.

Ceramide yog ib qho nruab nrab metabolite ntawm sphingolipids, thiab yog ib qho kev sib koom ua ke ntawm sphingolipids. Cov khoom no plays lub luag haujlwm tseem ceeb hauv biosynthesis. Cov tshuaj no muaj nyob rau hauv ib qho me me sab nraum platelets. Nyob rau tib lub sijhawm, cov khoom no yog ib chav kawm ntawm phospholipids nrog ceramide ua cov pob txha, feem ntau suav nrog ceramide phosphorylcholine thiab ceramide phosphorylethanolamine. Phospholipids yog cov khoom tseem ceeb ntawm cov cell membranes.

Txoj kev npaj ntawm ceramide

Muaj peb lub ntsiab extraction txoj kev ntawm ceramide: ntuj extraction, tshuaj synthesis, thiab microbial fermentation.

1. Natural extraction method

Natural extraction txoj kev yog tsuas yog muab rho tawm los ntawm cov tsiaj thiab nroj tsuag. Hauv cov tsiaj, cov tshuaj no feem ntau yog muab los ntawm lub hlwb ntawm cov tsiaj uas muaj kev pheej hmoo ntawm kab mob, tab sis ceramides rho tawm los ntawm cov khoom siv raw no tsis tuaj yeem siv rau hauv tshuaj pleev ib ce. Txawm li cas los xij, vim muaj kev txwv ntawm kev loj hlob ntawm cov nroj tsuag thiab lub caij nyoog, cov txiaj ntsig ntawm cov khoom muab rho tawm los ntawm cov nroj tsuag kuj tsawg.

2. Tshuaj synthesis

Cov khoom siv tshuaj sib xyaw ua ke feem ntau yog pseudoceramides, uas zoo sib xws hauv cov qauv thiab ua haujlwm rau ceramides. Cov tshuaj muab rho tawm hauv txoj kev no tuaj yeem siv rau hauv cov tshuaj pleev ib ce, thiab ntau yam pseudoceramides tau ua tiav tiav.

3. Microbial fermentation

Txoj kev no tau siv ntau txoj hauv kev los npaj cov ceramides hauv xyoo tas los no. Nws yog fermented nrog Pichia Serratia (Pichiaciferrii) los yog Saccharomyces cerevisiae (Saccharomyces cerevisiae) nyob rau hauv ib qho chaw tshwj xeeb, thiab ces tetra acetyl phytosphingosine (TAPS) tau txais; Tom qab ntawd, nws yog deacetylated kom tau txais phytosphingosine, thiab thaum kawg, ceramide thiab lwm yam tshuaj tuaj yeem raug tsim los ntawm kev ntxiv fatty acid.

Kev siv cov ceramide hauv tshuaj

Ceramide plays lub luag haujlwm tseem ceeb hauv cov teebmeem lom neeg uas raug ntxias los ntawm ntau yam cytokines, vitamin D3, Fas, thiab CD28 ligands, ntawm cov uas nws lub luag haujlwm hauv kev kho apoptosis tau nyiam ntau ntxiv; tib lub sijhawm, cov khoom lag luam kuj tseem koom nrog kev sib txawv ntawm tes thiab ntau lwm yam txheej txheem physiological.

Cov tshuaj tuaj yeem ua rau apoptosis ntawm epidermal keratinocytes thaum kab lis kev cai. Nyob rau tib lub sijhawm, cov khoom tseem yog cov khoom decomposition ntawm sphingomyelin nyob rau hauv lub bilayer ntawm cov kab mob lom, uas tau lees paub tias yog tus xa xov thib ob; Ceramides tseem ua lub luag haujlwm tseem ceeb hauv kev loj hlob ntawm tes, kev loj hlob, kev sib txawv, apoptosis thiab raug mob.

Kev siv cov hmoov ceramide hauv cov khoom noj

Niaj hnub no,ceramide hmoovtau tsim los rau hauv ntau yam zaub mov noj qab haus huv raws li qee qhov kev ua haujlwm ntawm lub cev. Cov zaub mov zoo li no muaj ntau yam cuam tshuam, xws li inhibiting nce ntshav siab, txhim kho kev tiv thaiv, thiab inhibiting lipase kev ua.

Cov khoom cog-raws li ceramide tau raug coj mus muag hauv xyoo 1998 thiab coj mus rau hauv khw. Txog tam sim no, cov khoom no feem ntau yog siv los ua cov khoom siv raw zoo ntxiv rau cov dej haus, cov ntsiav tshuaj, thiab lwm yam khoom noj khoom haus thiab cov zaub mov noj qab haus huv, tab sis nws tsis tshua siv hauv cov khoom.

Yuav tiv tauj peb li cas?

Peb yog cov kws tshaj lijCeramide hmoovtus neeg muag khoom. Peb lub tuam txhab muaj ntau yam khoom zoo thiab tsis tshua muaj nqi Hoobkas ncaj qha muag khoom, xws li cov nroj tsuag rho tawm, txiv hmab txiv ntoo thiab zaub hmoov, tshuaj pleev ib ce, ntsiav tshuaj candies, thiab lwm yam. Peb muaj txhua yam khoom. Yog tias koj txaus siab rau cov khoom no thiab xav yuav lossis xav paub cov ntaub ntawv khoom, koj tuaj yeem sab laj nrog peb, thiab peb yuav muaj cov neeg ua haujlwm tshaj lij los teb koj cov lus thaum koj pom cov xov xwm.

Yog tias koj xav tiv tauj peb, koj tuaj yeem tiv tauj peb tus thawj tswj hwm tus account los ntawm lub vev xaib thoob ntiaj teb lossis email,

Peb qhov chaw nyob e-mail yogella.zhang@huilinbio-tech.com ib. Tsis tas li ntawd, koj tuaj yeem tuaj xyuas lub Hoobkas. Peb lub Hoobkas chaw nyob yog Block B, Fengze Science thiab Technology Park, No. 170 West Street, Yanta District, Xi'an City, Shaanxi Province. Room 706, zoo siab txais tos.