Dab tsi yogTesamorelin
Tesamorelin(CAS 218949-}48-5) yog ib qho hluavtaws loj hlob hormone-releasing hormone (GHRH) analog muaj li ntawm 44 amino acids[1]. Nws tau raug tsim tshwj xeeb los ua cov haujlwm ntawm endogenous GHRH, yog li txhawb kev sib txuas thiab tso tawm ntawm kev loj hlob hormone (GH) los ntawm cov qog pituitary.[2]. Los ntawm kev khi rau GHRH receptors, tesamorelin txhawb nqa pulsatile GH tso tawm, uas tig los tswj cov tshuaj insulin-zoo li kev loj hlob ntawm 1 (IGF-1) ntau lawm, ua lub luag haujlwm tseem ceeb hauv kev tswj cov metabolism thiab cov txheej txheem anabolic.[2].
Cov peptide no tau raug tshawb fawb ntau, tshwj xeeb tshaj yog nyob rau hauv cov ntsiab lus ntawm metabolic ntshawv siab thiab lub cev muaj pes tsawg leeg kev hloov kho. Cov kev tshawb fawb tau tshawb nrhiav nws cov txiaj ntsig zoo hauv cov xwm txheej xws li HIV-koom nrog lipodystrophy, rog rog, thiab hnub nyoog- cuam tshuam GH poob, tsom rau nws lub peev xwm los txo cov visceral adipose cov ntaub so ntswg thiab txhim kho lipid profile yam tsis muaj kev cuam tshuam cov piam thaj metabolism.[3]. Nws cov phiaj xwm phiaj xwm muab kev tshawb fawb kom zoo dua kev tswj hwm GH ncaj qha los ntawm kev txhawb nqa ntau lub cev cov tshuaj hormone secretion.[2].
Kev tshawb nrhiav tsis tu ncua txuas ntxiv nthuav qhia txoj hauv kev molecular thiab ntev - cov teebmeem ntawm tesamorelin, ntxiv dag zog rau nws qhov tseem ceeb raws li lub cuab yeej rau kev nkag siab GH lub cev thiab nws cov peev xwm kho mob hauv endocrinology thiab kev tshawb fawb metabolic.[3].
Physicochemical Properties
| Khoom | Kev piav qhia |
|---|---|
| Khoom npe | Tesamorelin |
| Yam khoom tshwm | Dawb lyophilized hmoov |
| Molecular Formula | C₂₂₁H₃₆₆N₇₂O₆₇S |
| Molecular Luj | 5135.9 g / mol |
| CAS Nr | 218949-48-5 |
| Purity (HPLC) | >98.0% |
| Txee lub neej | 36 lub hlis raws li pom zoo cia |
| Solubility | Soluble nyob rau hauv sterile dej los yog bacteriostatic dej |
| Cia | Khaws ntawm -20 degree, tiv thaiv lub teeb thiab noo noo |
Cov yam ntxwv ntawm Tesamorelin
- Siab Purity: >98.0% txheeb xyuas los ntawm HPLC thiab huab hwm coj spectrometry
- Kev ruaj ntseg: Ua kom muaj kev ncaj ncees raws li kev pom zoo khaws cia
- Synthetic Keeb Kwm: Ua kom batch-rau-batch zoo ib yam thiab tsawg tsawg ntawm cov kab mob lom
- Qib tshawb fawb: Haum rau hauv vitro thiab tsiaj qauv kev kawm
Cov txiaj ntsig muaj peev xwm (Kev Tshawb Fawb Kev Tshawb Fawb)
Nco tseg: Cov ntaub ntawv hauv qab no yog muab los ntawm kev tshawb fawb preclinical luam tawm thiab yog muab rau kev tshawb fawb nkaus xwb. Cov khoom no tsis yog siv rau tib neeg lossis kev kuaj mob.
Cov kev tshawb fawb tshawb fawb tau txheeb xyuas ntau qhov chaw ntawm kev txaus siab rau Tesamorelin[2,3]:
- Kev tshawb nrhiav Endocrine System: Kev soj ntsuam ntawm kev loj hlob hormone tso tawm mechanisms thiab kev cai
- Kev tshawb fawb Metabolic: Tshawb nrhiav cov lipid metabolism thiab lub cev muaj pes tsawg leeg
- Receptor Interaction Studies: Kev tshuaj xyuas ntawm GHRH receptor binding thiab signaling pathways
- Hnub nyoog -Kev Tshawb Fawb Txog: Kev tshuaj xyuas ntawm endocrine muaj nuj nqi hauv kev sim ua qauv
Kev siv Tesamorelin
Tesamorelin txhawb ntau yam kev tshawb fawb tshawb fawb thoob plaws ntau yam kev qhuab qhia [1,3,5]:
- Kev Tshawb Fawb Kev Kawm: Ua hauj lwm hauv kev tshawb fawb physiological tsom rau kev loj hlob hormone tswj mechanisms thiab lawv cov kev cuam tshuam dav rau endocrine system muaj nuj nqi[3].
- Pharmaceutical Development: Ua haujlwm raws li cov ntaub ntawv siv thaum ntxov -theem tshawb fawb thiab kev txhim kho ntawm kev kho mob metabolic, tshwj xeeb tshaj yog cov uas muaj txoj hauv kev loj hlob hormone [5].
- Biochemical Mechanism Studies: Siv rau kev tshuaj xyuas peptide- receptor kev sib cuam tshuam dynamics thiab cov teeb liab txuas ntxiv mus hauv kev tswj chaw kuaj mob[1].
- Kev Tshawb Nrhiav Metabolic Initiative: Siv nyob rau hauv kev sim ua qauv tshawb xyuas lub cev muaj pes tsawg leeg kev tswj mechanisms thiab lub zog metabolism txheej txheem[3].
- Kev tshawb nrhiav endocrinology: Ua kom yooj yim rau txoj kev tshawb fawb ntawm pituitary caj pas ua haujlwm thiab cov kev tswj hwm cov tshuaj hormones hauv kev tshawb fawb physiological[5].
OME kev pabcuam
Peb muab kev pabcuam customized kom tau raws li qhov sib txawv ntawm cov neeg siv khoom:
◇ Cov kev pabcuam customization ntawm cov khoom sib txawv.
◇ Muab cov kev pab cuam ua hmoov. Xws li hmoov cov kaus poom capsules, hmoov compressed ntsiav tshuaj, thiab hais txog.
◇ Customized kev pab cuam ntawm lub ntim txheej, xws li ziplock hnab ntim, thiab ntim ntim ntim. Carton ntim, thiab lwm yam, thiab ntim tshwj xeeb xav kom cov neeg siv khoom tsim cov ntaub ntawv.
Ntim & Shipping
Hom Kev Thauj Khoom:
- Kev xa khoom sai: qhov rooj - mus rau - qhov rooj kev pabcuam
- Kev thauj huab cua: ceev ceev
- Kev thauj mus los hauv hiav txwv: tus nqi thauj khoom tsawg
Daim ntawv pov thawj
Cov lus nug nquag nug (FAQ)
Q: Puas yog Tesamorelin pom zoo rau tib neeg siv?
A: Thaum cov tshuaj formulations muaj nyob, cov khoom no yog nruj me ntsis rau kev tshawb fawb lub hom phiaj nyob rau hauv lub chaw soj nstuam xwb.
Q: Cov ntaub ntawv twg yog muab nrog cov khoom?
A: Tag nrho cov khoom suav nrog Daim Ntawv Pov Thawj Kev Ntsuam Xyuas kom paub meej purity thiab zoo specifications.
Q: Dab tsi yog lub sij hawm xa khoom rau kev txiav txim thoob ntiaj teb?
A: Feem ntau cov kev txiav txim tshawb fawb thoob ntiaj teb tau ua tiav hauv 7-15 hnub ua haujlwm nrog cov khoom siv txias txias.
Vim li cas thiaj xaiv peb?
✔ Peb tuaj yeem muab kev pabcuam rau koj, xws li OEM, thiab ODM cov kev pabcuam.
✔ Peb lav tias yog tias muaj teeb meem zoo, koj tuaj yeem rov qab los yog rov qab ua dua hauv ib hlis.
✔ Peb muaj kev tshaj lij cov khoom lag luam thiab cov khoom catalogs.
✔ Peb cov khoom muaj daim ntawv pov thawj ntawm kev tshuaj ntsuam xyuas los ntawm lub tuam txhab thoob ntiaj teb
✔ Thaum peb muaj cov khoom muag txaus, peb tuaj yeem xa cov khoom sai sai rau cov neeg siv khoom.
✔ Peb muaj pab pawg tshaj lij thiab kev paub nplua nuj
Cov ntaub ntawv
[1] National Center for Biotechnology Information. PubChem Compound Summary for CID 16165308
[2] Smit, P., & van der Lely, AJ (2010). Tus Kws Paub Txog Kev Kho Mob Biological, 10(12), 1701-1708
[3] Stanley, TL, & Grinspoon, SK (2012). Nature Reviews Endocrinology, 8(4), 243-253
[4] Cov kev tshawb fawb soj ntsuam txog cov teebmeem metabolic ntawm kev loj hlob hormone hloov pauv
[5] Kev tshawb fawb ntawm GHRH analog daim ntawv thov hauv cov kab mob endocrine
Tsis lees paub
Cov khoom no yog tsim los rau kev tshawb fawb lub hom phiaj nyob rau hauv kev tswj chaw kuaj ib puag ncig. Nws tsis yog npaj rau kev kuaj mob, kho, lossis siv tib neeg. Cov neeg yuav khoom yuav tsum xyuas kom ua raws li tag nrho cov kev cai lij choj thiab cov cai tswj xyuas kev muaj thiab siv cov kev tshawb fawb sib txuas. Xi'an Huilin Biological Technology Co., Ltd. xav tias tsis muaj kev lav phib xaub rau kev siv tsis raug lossis tsis raug tso cai tuav cov khoom no.
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