Taw qhia
D-Arginineyog qhov tsis yog -proteinogenic D-enantiomer ntawm semi-tseem ceeb amino acid L-arginine. Thaum L-arginine yog ib qho tseem ceeb hauv lub tsev thaiv kev koom tes hauv kev tsim nitric oxide thiab ntau txoj hauv kev metabolic, D-arginine tsis suav nrog rau hauv cov tsiaj cov protein. Cov cuab yeej sib txawv no txhawb nqa nws tus nqi raws li cov cuab yeej tshwj xeeb biochemical. Nws ua haujlwm raws li chiral tsev thaiv hauv cov organic thiab peptide chemistry, thiab cov kev tshawb fawb tawm tshiab qhia txog nws lub luag haujlwm lom neeg thiab catalytic hauv kev tshawb fawb tshawb fawb.
Physical & Chemical Parameters
| Parameter | Specification / Tus nqi | Lus Cim / Txoj Kev |
|---|---|---|
| Lub cev lub xeev | Khoom | Crystalline hmoov |
| Melting Point | 221 - 224 degree | Decomposes ntawm qhov kub siab dua. |
| Qhov ntom | 1.46 g / cm³ | Nyob rau hauv chav tsev kub. |
| Solubility hauv dej | Soluble | Nrog MSDS rau cov ntaub ntawv tshwj xeeb. |
| Specific Optical Rotation | Tsis zoo (rau D-(-)-form) | Tus cim tseem ceeb rau enantiomeric purity. |
| pKa | Siab pKa vim yog pab pawg guanidino | Impacts solubility thiab chemical reactivity. |
| Cia | Khaws ntawm 0-5 degree | Khaws lub thawv kaw kom nruj rau hauv qhov chaw qhuav thiab zoo- qhov cua. |
Mechanism ntawm Action
D-Arginine's mechanisms yog qhov sib txawv los ntawm nws cov L- sib piv, feem ntau yog los ntawm nws cov chirality thiab tsis yog-natural status nyob rau hauv mammalian biology.
- Chirality hauv Organic Catalysis:Ib daim ntawv thov tseem ceeb yog nws siv raws li ib qhoorganocatalyst. Kev tshawb fawb pom tau tias D-arginine tuaj yeem ua rau cov tshuaj tiv thaiv enantioselective organic, xws li cov synthesis ntawm anticoagulant warfarin. Qhov tseem ceeb, nws nthuav tawmrov qab enantioselectivity piv rau L-arginine, txaus siab rau kev tsim khoom ntawm (S)-warfarin enantiomer, qhia txog lub luag haujlwm tseem ceeb ntawm nws peb -seem qauv hauv tshuaj synthesis.
- Modulation ntawm Biological Pathways:Hauv kev tshawb fawb ntawm tes, D-arginine tau pom tias ua rau txo qis oxidative kev nyuaj siab thiab endothelial dysfunction induced los ntawm siab qabzib. Qhov tseem ceeb, cov nyhuv no tau pom zoo los ntawm ib qhoendothelial nitric oxide synthase (eNOS)-kev ywj pheej mechanism. Qhov no txawv ntawm L-arginine, uas feem ntau ua los ntawm L-Arg/NO txoj hauv kev.
- Tsev Block rau Bioactive Peptides:Qhov tshwj xeeb spatial orientation ntawm nws cov saw hlau ua rau D-arginine muaj txiaj ntsig hauv kev tsim thiab tsim cov hloov pauv peptides. Piv txwv li, koom nrog D-arginine ntawm cov haujlwm tshwj xeeb hauv peptide hormone analogues (piv txwv li, arginine-vasopressin analogues) tuaj yeem hloov pauv receptor binding affinity thiab selectivity, tso cai rau kev tsim cov phiaj xwm kev tshawb fawb ntau ntxiv nrog rau cov dej num tshwj xeeb.
Cov txiaj ntsig tseem ceeb & qhov zoo
- High Enantiomeric Purity:Muab qhov zoo-txhais tseg, ib leeg-enantiomer lub tsev thaiv rau qhov tseeb chiral synthesis thiab kev tshawb fawb.
- Unique Research Utility:Ua kom muaj kev tshawb fawb txog qhov tsis zoo ntawm cov txheej txheem lom neeg thiab ua haujlwm tswj tsis zoo hauv kev sim tshawb nrhiav L-arginine- txoj hauv kev.
- Ntau yam Synthetic Intermediate:Qhov tseem ceeb rau kev npaj tsis yog -natural peptides, complex organic molecules, thiab kev tshawb fawb tshwj xeeb.
- Tsim Kev Nyab Xeeb Profile:Ua raws li tus qauv kuaj tshuaj nrog zoo - yam ntxwv kev ceev faj txog kev nyab xeeb.
Cov ntawv thov tseem ceeb
D-Arginine pom kev siv tshwj xeeb hauv kev tshawb fawb qib siab thiab cov khoom siv hluavtaws.
| Kev lag luam/ teb | Piv txwv daim ntawv thov | Lub luag haujlwm & Cov txiaj ntsig |
|---|---|---|
| Organic Chemistry & Catalysis | Enantioselective organocatalysis (xws li warfarin synthesis); chiral synthon nyob rau hauv complex molecule synthesis. | Muab qhov tshwj xeeb chiral ib puag ncig los tswj cov tshuaj tiv thaiv stereochemistry. |
| Biochemistry & Cell Research | Kawm txog endothelial dysfunction thiab oxidative kev nyuaj siab ntawm tsis yog -NOS txoj kev; tswj cov amino acid metabolism hauv kev tshawb fawb. | Muab cov cuab yeej los txiav cov txheej txheem ywj pheej ntawm classical L-arginine signaling. |
| Pharmaceutical & Peptide Research | Synthesis ntawm hloov peptide analogs (piv txwv li, vasopressin analogues); kev loj hlob ntawm cell-peptides nkag mus. | Hloov kho peptide stability, kev ua, thiab receptor selectivity. |
| Kev Tshawb Fawb Txog Kev Tshawb Fawb | Cov qauv siv rau chromatography; chiral resolving agent. | Ua kom paub tseeb tseeb thiab sib cais ntawm enantiomers. |
FAQ: Cov lus nug nquag nug
Q: Dab tsi yog qhov txawv ntawm D-Arginine thiab L-Arginine?
A: Lawv tsis yog - cov duab iav superimposable (enantiomers). L-Arginine yog lub ntuj tsim, proteinogenic amino acid nyob rau hauv tib neeg lub cev (xws li, TSIS MUAJ synthesis, urea voj voog). D-Arginine feem ntau tsis siv los ntawm cov tsiaj nyeg rau kev tsim cov protein, tab sis muaj cov ntawv thov sib txawv hauv kev tshawb fawb raws li chiral catalyst, ib qho cuab yeej rau kev soj ntsuam cov txheej txheem lom neeg, thiab lub tsev thaiv rau cov peptides hluavtaws.
Q: D-Arginine puas tuaj yeem siv los ua kev noj zaub mov zoo li L-Arginine?
A: Tsis yog. D-Arginine tsis yog npaj rau tib neeg noj raws li kev noj haus ntxiv. Nws yog muag nruj me ntsis rau kev tshawb fawb thiab kev tsim khoom. Nws txoj hmoo metabolic thiab cov teebmeem lom neeg txawv ntawm L-arginine.
Q: Puas yog D-Arginine muaj kev nyab xeeb los daws?
A: Nws yog ib qho chaw kuaj tshuaj. Raws li cov ntaub ntawv kev nyab xeeb, nws ua rau mob qhov muag loj (H319). Nco ntsoov xa mus rau Daim Ntawv Qhia Kev Nyab Xeeb (SDS) thiab siv cov cuab yeej tiv thaiv tus kheej tsim nyog (PPE), suav nrog tsom iav thiab hnab looj tes.
Q: Yuav ua li cas D-Arginine hmoov yuav khaws cia?
A: Rau qhov zoo tshaj plaws ntev -lub sij hawm ruaj khov, khaws cia hauv lub thawv ntim qub ntawm 0-5℃(txias). Tiv thaiv los ntawm noo noo thiab lub teeb.
Q: "D-(-)-Arginine" txhais li cas?
A: "D" qhia txog qhov tseeb ntawm cov molecule nyob ib ncig ntawm nws qhov chaw chiral. "(-)" yog hais txog nws qhov kev sib hloov kho qhov muag tsis zoo, lub ntsiab lus nws tig dav hlau-polarized teeb rau sab laug (levorotatory). Qhov no yog ib qho khoom tseem ceeb ntawm lub cev uas lees paub nws tus kheej thiab kev coj dawb huv.
Tiv tauj peb
Peb cov hwm D-Arginine hmoov yog tsim los ntawm kev tswj xyuas nruj, kom ntseeg tau tias muaj tshuaj lom neeg thiab enantiomeric purity rau kev ntseeg siab, rov tsim dua tshiab hauv koj daim ntawv thov xav tau tshaj plaws.
Hu rau peb pab neeg muag khoom hnub no rau:Tau txais kev sib tw nqe lus rau qhov ntau los ntawmgrams rau kilograms.
Txhim kho koj cov kev tshawb fawb thiab kev sib txuas ua ke nrog qhov chaw cia siab rau cov amino acids tshwj xeeb.
Thov hu rau peb ntawmella.zhang@huilinbio-tech.com.
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