Taw qhia
4,5-Dimethylthiazoleyog ib qho heterocyclic organic compound uas muaj nyob rau tsev neeg thiazole, tus yam ntxwv los ntawm tsib-ntiv nplhaib uas muaj cov sulfur thiab nitrogen atoms. Nws yog ib tug siab - cuam tshuam aroma tshuaj renowned rau nwshaib roasted, nutty, thiab meaty tsw profile nrog txawv nqaij nruab deg nuances, uas tau txais nws lub npe hu ua kev lag luam"Nqaij Thiazole".
Qhov sib xyaw no yog ib txwm tshwm sim thiab tau tshaj tawm nyob rau hauv ntau yam khoom noj, suav nrogpeanuts, toasted oats, malt, txiv duaj, nqaij npuas, kas fes, krill, cws, thiab scallops. Nws qhov xwm txheej tshwm sim hauv cov zaub mov siav thiab ua tiav ua rau nws yog ib qho cuab yeej tseem ceeb rau cov kws tshaj lij nrhiav kev tsim cov khoom noj qab zib tiag tiag, ci, thiab nqaij nruab deg.
Nrog rau keeb kwm ntev ntawm kev siv nyab xeeb, 4,5-Dimethylthiazole tau pom zoo los ntawm cov koom haum tswj hwm thoob ntiaj teb, suav nrogUS FDA, FEMA (GRAS 3274), thiab JECFA, which concluded there is "no safety concern at current levels of intake when used as a flavoring agent". Our product is offered at high purity (>98%) los xyuas kom meej qhov ua tau zoo thiab ua raws li cov qauv thoob ntiaj teb thiab cov tshuaj tsw qab.
Physical & Chemical Parameters
| Parameter | Specification / Tus nqi | Sau ntawv / Reference |
|---|---|---|
| Lub cev lub cev (20 degree) | Ua kua | Ntshiab, tsis muaj xim rau daj ntseg daj |
| Purity (GC) | Ntau dua lossis sib npaug li 98.0% | >98.0% specification |
| Boiling Point | 157-159℃ntawm 760 mmHg | 158℃ntawm 742 mmHg |
| Melting Point | 83-84 degree | Cov ntaub ntawv muaj nqis |
| Flash Point | 51 ° F (124 ° F) | Kaw khob; flammable kua |
| Ceev / Specific Gravity | 1.067 – 1.072 | Thaum 20 degree |
| Refractive Index (n20/D) | 1.516 – 1.524 | |
| LogP (XLogP3-AA) | 1.8 | xam |
| Solubility hauv dej | Tsawg | Tsis yooj yim soluble |
| Solubility hauv Organic Solvents | Soluble hauv ether; miscible nrog ethanol ntawm chav tsev kub | |
| pKa | 3.73 (25 degree, μ=0.1) | |
| Hazard Classification | GHS02, GHS07 | Flammable kua (Cat 3), Irritant |
| Cov Lus Qhia Txog Hazard | H226, H302, H315, H319 | Flammable kua thiab vapor; teeb meem yog nqos; ua rau tawv nqaij thiab qhov muag khaus |
| UN Number | UN 1993 | Chav Kawm 3, Packing Group III |
Mechanism ntawm Action
4,5-Dimethylthiazole ua haujlwm los ntawm ob lub tswv yim tseem ceeb: kev sib cuam tshuam ntawm kev hnov qab ua tus neeg sawv cev tsw thiab tshuaj lom neeg ua haujlwm raws li cov khoom siv hluavtaws.
A. Mechanism li Flavoring Agent
Raws li tus neeg sawv cev flavoring, 4,5-Dimethylthiazole exerts nws cov teebmeem los ntawm kev sib cuam tshuam ncaj qha nrog olfactory thiab saj receptors. Nws cov sulfur-muaj thiazole nplhaib qauv yog ib qho chaw muag tshuaj rau savory, roasted, thiab meaty tsw sau ntawv. Ntawm qhov tsis tshua muaj siab (ib feem ntawm ib lab ntau), nws ua raws li lub zog hloov pauv, ntxiv qhov tob thiab qhov tseeb rau cov khoom noj qab zib nrog rau qhov pib ntawm 470 ppb.
B. Mechanism li Chemical Intermediate
Raws li tshuaj lom neeg nruab nrab, thiazole core ua haujlwm ntau yam hauv kev sib txuas. Nws tau nkag mus rau radical bromination nrog N-bromosuccinimide (NBS) kom tawm los mono-, tri-, thiab tetrabromo derivatives nrog regioselectivity (5-Me > 4-Me > C-2)[1][2]. Nws koom nrog ntau yam kev cuam tshuam, suav nrog oxidation (ua sulfoxides thiab sulfones), txo qis (ua thiazolidines), thiab hloov cov tshuaj tiv thaiv.
Cov txiaj ntsig tseem ceeb & qhov zoo
- Authentic Savory & Seafood Profile:Muab cov roasted, nutty, meaty, thiab cws -zoo li tus cwj pwm tseem ceeb rau kev tsim cov nqaij tiag tiag, nqaij qaib, thiab tshwj xeeb tshaj yog cov nqaij nruab deg (qws, krill, scallops).
- High Potency:Ua pov thawj qhov pib tsw qab (470 ppb), tsuas yog yuav tsum tau siv tsawg kawg nkaus kom ua tiav qhov cuam tshuam tseem ceeb, muab cov nqi zoo heev -hauv - siv tus nqi.
- Ntxim tshwm sim Profile:Nws lub xub ntiag nyob rau hauv cov khoom noj ntuj (qws, nqaij npuas, kas fes, txiv laum huab xeeb) txhawb kev tsim cov txheej txheem ntuj tsim thiab qhov tseeb.
- Kev lees paub thoob ntiaj teb:Muaj qhov zoo -tsim muaj kev nyab xeeb profile nrogFEMA GRAS (3274)Raws li txoj cai, FDA pom zoo, thiab kev soj ntsuam zoo JECFA lees paub tias tsis muaj kev txhawj xeeb txog kev nyab xeeb ntawm qib noj tam sim no[3].
- Versatile Application Range:Haum rau ntau yam khoom noj khoom haus, los ntawm cov kua zaub thiab gravy mus rau cov khoom ci, khoom noj txom ncauj, thiab khoom noj siv mis.
- High Purity & Consistency:Muaj ntau dua los yog sib npaug rau 98% purity, kom ntseeg tau batch-rau-batch kev ntseeg siab rau ruaj khov thiab kwv yees cov tshuaj tsw qab.
Cov ntawv thov tseem ceeb
4,5-Dimethylthiazole yog cov khoom muaj txiaj ntsig zoo siv dav hauv kev lag luam zaub mov thiab tsw.
| Qeb zaub mov | Piv txwv daim ntawv thov | Kev Pabcuam Sensory |
|---|---|---|
| Khoom noj khoom haus & Nqaij | Cov nqaij flavors (nqaij nyuj, nqaij npuas, nqaij qaib), cov nqaij ua tiav, hnyuv ntxwm, bouillons, stocks | Ntxiv roasted, siav nqaij cim; txhim kho savory tob |
| Seafood Flavors | Cw, krill, scallop, crab, thiab dav dav seafood flavorings | Muab qhabnias "qhib thiazole" daim ntawv; mimics siav nqaij nruab deg aroma |
| Soups, Sauces & Gravies | Cov kaus poom thiab qhuav kua zaub, ntub thiab qhuav kua ntses, gravy mix, seasonings | Round tawm savory profiles; ntxiv complexity thiab nplua nuj |
| Khoom noj txom ncauj | Qos yaj ywm chips, extruded khoom noj txom ncauj, savory crackers, flavored paj kws | Imparts roasted thiab grilled sau ntawv; txhim khu tag nrho cov khoom noj txom ncauj savoriness |
| Cov khoom siv mis nyuj | Cheese flavors, tiav cheese, mis nyuj dips, khov mis nyuj khov | Pab txhawb nutty thiab siav sau ntawv; pab tau nyob rau hauv savory siv mis nyuj |
| Bakery & Cereals | Ci khoom, noj tshais cereals, crackers | Ntxiv toasty, ci aroma reminiscent ntawm roasted nplej thiab ceev |
| Seasonings & Condiments | Qhuav seasoning blends, marinades, rubs, mayonnaise, zaub xam lav hnav khaub ncaws | Muab cov ntawv sau keeb kwm yav dhau los; txhim khu kev nkag siab umami |
| Dej haus (Alcoholic & Non{0}}alcoholic) | Savory cocktail mixes, Bloody Mary mixes, zaub kua txiv | Ntxiv complexity thiab savory tob rau cov dej haus systems |
| Pharmaceutical Research | Intermediate hauv synthesis ntawm bioactive molecules | Lub tsev thaiv rau kev tshawb nrhiav tshuaj thiab kev txhim kho |
Formulation & Handling Reference
- Hom Kev Siv Qib:Raws li ib tug muaj zog flavoring neeg sawv cev, 4,5-Dimethylthiazole feem ntau yog siv nyob rau hauv tsawg concentrations.
Khoom noj khoom haus tiav:1 - 10 ppm (mg / kg), nyob ntawm daim ntawv thov thiab qhov xav tau siv.
Flavour Concentrates:0.1% - 1.0% nyob rau hauv qab formulations, hloov mus rau lub hom phiaj siv theem nyob rau hauv cov khoom noj zaum kawg.
Saj Yam ntxwv:Ntawm 5 ppm, nws nthuav tawm fishy, amine, thiab pyridine -zoo li sau ntawv nrog cws thiab savory nuances .
- Solubility Qhia:Miscible nrog ethanol thiab soluble nyob rau hauv feem ntau cov organic solvents thiab taag roj. Soluble tsis zoo hauv dej. Rau cov tshuab aqueous, ua ntej - yaj hauv cov kuab tshuaj uas tsim nyog (xws li ethanol, propylene glycol) ua ntej koom ua ke.
- Kev koom ua ke:Qhov zoo tshaj plaws ntxiv thaum lub sij hawm sib xyaw ua ke los yog rau cov roj theem ntawm emulsions. Rau cov khoom sib tov qhuav, nws tuaj yeem muab plated rau hauv cov cab kuj (piv txwv li, maltodextrin, ntsev, qab zib) kom ntseeg tau tias cov khoom sib txawv.
- Cia & Stability:Khaws cia rau hauv qhov chaw kaw ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntim cov thawv ntim khoom tiv thaiv lub teeb<15°C recommended). Flammable liquid (Flash point: 51°C). Keep away from heat, sparks, and open flames. Stable under recommended storage conditions. Protect from prolonged exposure to air and light to prevent degradation .
- Kev Tiv Thaiv Kev Nyab Xeeb:Siv qhov cua kom txaus. Hnav cov khoom tiv thaiv tus kheej tsim nyog ( hnab looj tes, tsom iav kev nyab xeeb). Xa mus rau Safety Data Sheet (SDS) kom paub meej txog kev tuav thiab cov ntaub ntawv xwm txheej ceev.
FAQ: Cov lus nug nquag nug
Q: 4,5-Dimethylthiazole tsw thiab saj zoo li cas?
A: Nws muaj cov yam ntxwv ci, nutty, meaty, thiab boiled poultry -zoo li tsw, nrog txawv ntses thiab cws -zoo li (krill) nuances . Ntawm kev siv qib hauv cov zaub mov, nws muab cov khoom qab zib, nqaij nruab deg-zoo li saj nrog cov ntawv ci thiab cov ntawv sau.
Q: Vim li cas qee zaum nws hu ua "Chip Thiazole"?
A: Lub npe kev lag luam no muab los ntawm nws cov cw muaj zog -zoo li tus cwj pwm aroma. Nws yog lub luag haujlwm tseem ceeb ntawm cov cw siav thiab nqaij nruab deg tsw profile thiab muaj nyob hauv cws, krill, thiab scallops.
Q: Puas yog 4,5-Dimethylthiazole zoo siv rau hauv cov khoom noj?
A: Yog. Nws yog ib qho kev pom zoo flavoring tshuaj uas muaj keeb kwm ntev ntawm kev siv nyab xeeb. Nws tau teev los ntawm US FDA raws li cov khoom siv ntxiv rau cov khoom noj (flavoring agent lossis adjuvant), muaj FEMA GRAS raws li txoj cai (No. 3274), thiab tau raug soj ntsuam los ntawm JECFA, uas xaus lus tias tsis muaj "tsis muaj kev txhawj xeeb txog kev noj qab haus huv tam sim no thaum siv los ua tus neeg sawv cev flavoring".
Q: Dab tsi yog qhov pom zoo npaum li cas rau daim ntawv thov zaub mov?
A: Feem ntau siv hauv cov khoom noj khoom haus tiav ntawm 1 txog 10 feem ntawm ib lab (ppm). Cov qib zoo nyob ntawm daim ntawv thov thiab qhov xav tau qhov profile. Ntawm 5 ppm, nws nthuav tawm nws cov yam ntxwv ntses thiab cws -zoo li saj . Nws muaj zog heev, yog li tsis tshua muaj siab concentration.
Q: 4,5-Dimethylthiazole tshwm sim nyob qhov twg?
A: Nws tau raug txheeb xyuas tias yog ib qho tshwm sim nyob rau hauv ntau yam khoom noj, xws li txiv laum huab xeeb, toasted oats, malt, txiv duaj, nqaij npuas, kas fes, krill, cws, thiab scallops. Nws tsim feem ntau cuam tshuam nrog cov tshuaj tiv thaiv Maillard thaum ua noj lossis ci.
Q: Cov khoom no puas yog ntuj?
A: Peb cov khoom lag luam yog tsim los ntawm synthetically thiab chemically zoo tib yam rau cov molecule pom nyob rau hauv cov xwm. Nws raug cais raws li qhov xwm txheej - zoo ib yam khoom tsw qab. Ntuj versions yuav muaj raws li qhov kev thov tshwj xeeb thiab tsim nyog.
Q: Kuv yuav khaws cov khoom no li cas?
A: Khaws rau hauv lub thawv kaw nruj nreem, tiv thaiv los ntawm lub teeb, hauv qhov chaw txias thiab tsaus (qhov kub qis dua 15℃pom zoo). Vim nws qhov taw tes ntawm 51 degree, nws raug cais raws li cov kua hluav taws xob thiab yuav tsum tau khaws cia kom deb ntawm tshav kub, sparks, thiab qhib nplaim taws.
Q: Dab tsi yog qhov tseem ceeb ntawm kev phom sij?
A: Nws raug cais raws li GHS02 (Flammable) thiab GHS07 (Irritant). Nws muaj teeb meem yog tias nqos tau (H302), ua rau tawv nqaij khaus (H315), thiab ua rau qhov muag khaus loj (H319). Nco ntsoov sab laj nrog SDS ua ntej tuav.
Ua tam sim no
Txhawb nqa koj cov nqaij, nqaij nruab deg, thiab cov khoom qab zib nrog peb cov siab -purity 4,5-Dimethylthiazole. Rov qab los ntawm kev pom zoo thoob ntiaj teb kev tswj hwm thiab ntau xyoo ntawm kev siv nyab xeeb, nws yog qhov kev xaiv ntseeg siab rau cov neeg nyiam thoob ntiaj teb nrhiav cov qhabnias roasted thiab cw-zoo li profiles.
Hu rau peb pab neeg muag khoom hnub no rau:
- Thov ib qho qauv rau koj qhov kev txhim kho tsw thiab kev ntsuam xyuas.
- Tau txais cov lus sib tw rau R&D, pilot- ntsuas qhov ntsuas, lossis kev xav tau ntau lawm.
Thov hu rau peb ntawmella.zhang@huilinbio-tech.com.
Cov ntaub ntawv
- Domard, M., Peters, D., Hariri, MA, Pautet, F., Fillion, H., & Chermette, H. (2000). Ib qho piv txwv ntawm kev xaiv dawb -radical bromination ntawm 4,5-dimethyl-thiazole nrog N-bromosuccinimide.Phau ntawv Journal of Molecular Structure: THEOCHEM, *499*(1-3), 141–149.
- Al Hariri, M., Galley, O., Pautet, F., & Fillion, H. (1998). Selective Bromination ntawm 4,5-Dimethylthiazole nrog N-Bromosuccinimide.European Journal of Organic Chemistry, *1998*(4), 593–595.
- US Food and Drug Administration. (2025). Cov Tshuaj Ntxiv rau Khoom Noj (yav tas los EAFUS): 4,5-DIMETHYLTHIAZOLE.
Cim npe nrov: 4,5-dimethylthiazole kua, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, ntuj, zoo, Tshuag, kev muag
