Pyridoxine Hydrochloride (Vitamin B6) yog dab tsi?
Vitamin B6 (pyridoxine)yog dej- cov vitamin soluble tseem ceeb rau tib neeg lub cev, ua lub luag haujlwm tseem ceeb hauv ntau cov txheej txheem metabolic thoob plaws hauv lub cev. Daim ntawv ua haujlwm lom neeg, pyridoxal 5'-phosphate (PLP), ua haujlwm ua coenzyme nyob rau hauv ntau dua 160 cov haujlwm enzymatic tshwj xeeb feem ntau koom nrog hauv amino acid, carbohydrate, thiab lipid metabolism [2][8]. Tsis zoo li ntau lwm cov vitamins, vitamin B6 tsis tuaj yeem tsim los ntawm tib neeg lub cev thiab yuav tsum tau txais los ntawm kev noj zaub mov los yog ntxiv. Kev tsis txaus tuaj yeem tshwm sim los ntawm kev noj zaub mov tsis zoo, malabsorption, haus dej cawv ntev, kab mob raum, thiab kev cuam tshuam nrog qee yam tshuaj xws li isoniazid thiab tshuaj tiv thaiv kab mob.
Vim li cas thiaj xaiv Pyridoxine Hydrochloride?
Pyridoxine hydrochloride yog qhov ruaj khov tshaj plaws, tus nqi - siv tau, thiab siv dav hauv cov vitamin B6 rau kev siv hmoov ntau. Nws yog daim ntawv nyiam tshaj plaws rau kev tiv thaiv zaub mov, kev noj zaub mov noj, thiab cov tshuaj tsim tshuaj thoob ntiaj teb vim nws cov dej solubility zoo heev, bioavailability siab, thiab zoo -tsim kom muaj kev pom zoo. Nws feem ntau lees paub tias muaj kev nyab xeeb (GRAS) los ntawm US Food and Drug Administration nyob rau hauv 21 CFR §184.1676 thiab ua raws li USP, EP, FCC, thiab zaub mov- qib specifications.
Biochemical & Physical Parameters
| Khoom | Tus nqi |
|---|---|
| CAS Nr | 58-56-0 |
| Tus lej EC (EINECS) | 200-386-2 |
| Molecular Formula | C₈H₁₂ClNO₃ |
| Molecular Luj | 205.64 g / mol |
| Qhov tshwm sim | Dawb rau tawm -dawb crystalline hmoov |
| tsw / Saj | Tsis hnov tsw, tsw |
| Melting Point | 205-214℃(decomposes) |
| Solubility hauv dej | 1 g dissolves nyob rau hauv kwv yees li 4.5 mL dej - ntshiab, tsis muaj xim mus rau daj ntseg kua; Ntau dua lossis sib npaug li 50 mg / mL (243 mM) |
| Solubility hauv Cawv | 1 g dissolves nyob rau hauv kwv yees li 90 mL ethanol |
| Solubility hauv DMSO | Ntau dua lossis sib npaug li 50 mg / mL (243 mM) |
| Insolubility | Ether, chloroform, acetone |
| Qhov ntom | 0.8g / cm³ |
| pH (5% aq.) | 2.3 – 3.5 |
| Poob rau ziab | Tsawg dua lossis sib npaug li 0.5% |
| Sulphated tshauv / Residue ntawm Ignition | Tsawg dua lossis sib npaug li 0.1% |
| Heavy Metals (Pb) | Tsawg dua lossis sib npaug li 0.003% |
| Cov ntsiab lus chloride | 16.9 - 17.6% (qhuav qhuav) |
| Assay (NT/HPLC) | 98.0 - 102.0% (ntawm qhuav hauv paus) |
| Cia kub | Chav ntsuas kub (8-25℃/ +4 txog +30 degree) |
| Kev cia khoom | Qhov chaw txias, qhuav, tiv thaiv los ntawm lub teeb, khaws lub thawv kaw kom nruj |
| Txee lub neej | 60 muaj |
| GHS Hazard Classification | GHS05 (Ua rau qhov muag loj heev); Cov txheej txheem kuaj kev ceev faj siv tau |
Mechanism ntawm Action
Vitamin B6 ua haujlwm ua ntau yam "pab pawg" (coenzyme) rau ntau tshaj 160 enzymes hauv lub cev, feem ntau los ntawm nws daim ntawv hu uapyridoxal 5'-phosphate (PLP). Xav txog PLP ua cov haujlwm ua haujlwm uas tso cai rau cov enzymes ua lawv txoj haujlwm kom raug.
Nws ua haujlwm li cas:
1. Amino Acid ua- PLP ua cov cofactor rau cov enzymes uas tsim, tawg, thiab hloov cov amino acids. Cov tshuaj tiv thaiv tseem ceeb tshaj plaws yogtransamination, uas tso cai rau lub cev hloov ib qho amino acid rau lwm tus, thiabdecarboxylation, uas pab tsim cov neurotransmitters tseem ceeb.
2. Neurotransmitter Synthesis- PLP pab cov enzymes tsim cov tshuaj hlwb tseem ceeb uas tswj kev xav, pw tsaug zog, thiab kev txawj ntse. Piv txwv li, nws yuav tsum tau ua rau serotonin (qhov "xav- zoo" neurotransmitter) thiab dopamine (muaj feem xyuam rau kev txhawb siab thiab txaus siab), nrog rau GABA (uas calms lub paj hlwb).
3. Homocysteine Regulation- PLP koom nrog hauv cov metabolism ntawm homocysteine , ib qho amino acid uas, thaum muaj nyob rau hauv siab, tuaj yeem ua rau cov hlab ntsha puas tsuaj thiab ua rau muaj kev pheej hmoo ntawm cov hlab plawv. Vitamin B6 pab kom cov qib homocysteine nyob rau hauv ib tug noj qab haus huv ntau yam.
4. Glycogen tawg- PLP ua haujlwm nrog lub enzyme hu uaglycogen phosphorylasetxhawm rau txhawm rau khaws cia glycogen rau hauv qabzib, muab lub zog thaum lub cev xav tau.
5. Lub cev muaj zog- Vitamin B6 yog qhov tsim nyog rau kev tsim cov tshuaj tiv thaiv kab mob thiab kev ua haujlwm ntawm lub cev tiv thaiv kab mob, pab lub cev tiv thaiv kab mob.
Nyob rau hauv ib tug nutshell:Vitamin B6 zoo li tus yuam sij uas qhib ntau pua cov tshuaj tiv thaiv hauv koj lub cev - nws pab zom cov protein, txhawb kev xav thiab lub hlwb ua haujlwm, tiv thaiv koj lub plawv, tsim lub zog, thiab ua kom koj lub cev tsis muaj zog.
Cov txiaj ntsig kev noj qab haus huv
1 Txhawb nqa lub paj hlwb thiab lub hlwb ua haujlwm
Vitamin B6 yog qhov tseem ceeb rau kev loj hlob ntawm lub hlwb thiab ua kom lub paj hlwb noj qab haus huv. Raws li qhov xav tau cofactor rau cov enzymes koom nrog hauv neurotransmitter synthesis, B6 txhawb kev tsim cov tshuaj hlwb tseem ceeb xws li serotonin, dopamine, thiab GABA, uas tswj kev xav, pw tsaug zog, thiab kev txawj ntse. Kev tsim nyog ntawm cov vitamin B6 tuaj yeem pab txhim kho kev xav, txo cov tsos mob ntawm kev nyuaj siab, thiab txhim kho kev txawj ntse. Cov vitamin kuj txhawb kev tsim myelin - cov ntaub thaiv tiv thaiv ib puag ncig cov paj hlwb uas ua rau cov paj hlwb xa mus sai.
2 Txhawb Kev Noj Qab Haus Huv Ntawm Cov Kab Mob
Vitamin B6 pab tswj qib ntawm homocysteine , ib qho amino acid cuam tshuam nrog kab mob plawv. Cov ntshav ntshav siab homocysteine tau lees paub tias yog ib qho kev pheej hmoo ntawm kev mob plawv, thiab vitamin B6 (ua ke nrog folate thiab B12) pab txhawb kev hloov pauv ntawm homocysteine rau methionine, yog li pab tswj cov qib homocysteine zoo. Ib qho kev tshuaj ntsuam meta- tau pom tias cov tib neeg uas muaj vitamin B6 tsawg muaj 1.5-fold muaj kev pheej hmoo ntawm cov kab mob plawv.
3 Boosts Immib Function
Vitamin B6 txhawb kev tiv thaiv kab mob los ntawm kev pab tsim cov tshuaj tiv thaiv kab mob thiab tswj cov kab mob lymphoid, yog li pab txhawb kev noj qab haus huv tag nrho thiab tiv thaiv kab mob. Nws yog ib qho tseem ceeb rau kev ua haujlwm zoo ntawm lub cev tiv thaiv kab mob thiab pab lub cev ua kom cov lus teb zoo tiv thaiv kab mob.
4 Sibrts Zog Metabolism
Raws li cov cofactor hauv glycogen tawg thiab ntau txoj hauv kev metabolic, vitamin B6 plays lub luag haujlwm tseem ceeb hauv kev hloov cov carbohydrates, cov protein, thiab cov rog mus rau hauv lub zog siv tau ntawm tes. Cov tib neeg uas tsis muaj B6 feem ntau muaj kev qaug zog thiab qaug zog; supplementation pab restore lub zog ib txwm muaj.
5 Pab txhawb rau Hemethiab kev tsim cov qe ntshav liab
Vitamin B6 yog xav tau rau kev sib txuas ntawm heme, hlau - muaj cov hemoglobin hauv cov qe ntshav liab. Kev tsim nyog ntawm cov vitamin B6 pab tiv thaiv qee hom ntshav qab zib thiab txhawb kev noj qab haus huv ntawm cov qe ntshav liab.
6 Modulates Inflamation thiab Txo Oxidative Stress
Vitamin B6 muaj antioxidant zog thiab muaj peev xwm txo qis glycation kawg khoom (AGE) qib. Nws ua lub luag haujlwm hauv kev txo qis oxidative kev nyuaj siab thiab inhibiting o, uas yog cov hauv paus ntsiab lus ntawm ntau yam kab mob.
7 Txhawb kev xeeb tubthiab Hormone Regulation
Vitamin B6 tau lees paub rau nws lub luag haujlwm hauv kev tswj kev xeev siab thaum cev xeeb tub, feem ntau hu ua "mob thaum sawv ntxov". Nws kuj tseem ua lub luag haujlwm hauv kev tswj hwm cov tshuaj hormones thiab tau siv los kho cov tsos mob ntawm tus mob premenstrual syndrome.
Cov ntsiab lus ntawm cov pov thawj kho mob:A 2025 kev tshuaj xyuas hauv lubPhau ntawv Journal of Future Foodslees paub vitamin B6 lub luag haujlwm hauv kev tswj hwm homocysteine metabolism, txo oxidative kev nyuaj siab, inhibiting o, thiab txhawb DNA kho, nrog rau cov kev cuam tshuam loj rau cov kab mob plawv, ntshav qab zib, neurodegenerative disorders, thiab COVID-19-txog cov teeb meem. Ib xyoo 2021 PMC tshuaj xyuas ntxiv qhia txog nws txoj kev koom tes hauv ntau dua 150 cov tshuaj lom neeg biochemical thoob plaws carbohydrate, lipid, amino acid, thiab nucleic acid metabolism. Tsis tas li ntawd, kev tshuaj xyuas tshuaj 2025 tau luam tawm hauvSaudi Journal of Medical and Pharmaceutical Sciencespaub meej vitamin B6 lub luag haujlwm tseem ceeb hauv kev sib txuas neurotransmitter, amino acid metabolism, thiab nws FDA- pom zoo siv rau xeev siab thaum cev xeeb tub.
Daim ntawv thov
1 Khoom noj khoom haus
High-purity Vitamin B6 hmoov yog ib qho tseem ceeb muaj nyob rau hauv multivitamin ntsiav tshuaj thiab tsiav tshuaj, standalone B6 tshuaj, sublingual sprays, kua tee, gummy vitamins, thiab effervescent ntsiav tshuaj. Cov neeg uas muaj kev txwv tsis pub noj zaub mov, cov kab mob metabolic, lossis kev noj zaub mov ntau ntxiv yuav tsum tau tiv thaiv qhov tsis txaus.
2 Functional Foods thiab dej haus
Pyridoxine hydrochloride yog dav siv los ua kom muaj zog noj tshais, cereal bars, khoom noj khoom haus, dej haus, protein hmoov, khoom noj siv mis, mis nyuj, lwm yam khoom noj khoom haus, thiab khoom noj khoom haus dej haus. FCC qib raws li Food Chemical Codex cov cai thiab tsim nyog rau txhua daim ntawv thov zaub mov, dej haus, thiab khoom noj khoom haus ntxiv.
3 Pharmaceuticib Formulations
USP-qib vitamin B6 hmoov ua haujlwm ua cov tshuaj muaj txiaj ntsig (API) hauv cov tshuaj txhaj tshuaj intramuscular, ntsiav tshuaj ntawm qhov ncauj, thiab cov khoom siv tshuaj sib xyaw ua ke. Nws yog siv los kho tej yam mob xws li pyridoxine- mob vwm, peripheral neuropathy, qee yam mob ntshav qab zib, thiab isoniazid overdose, thiab yog FDA- pom zoo nyob rau hauv cov khoom ua ke rau xeev siab thaum cev xeeb tub.
4 Infant Formula
Pyridoxine hydrochloride tuaj yeem siv rau hauv cov mis mos rau kev loj hlob ntawm lub paj hlwb raws li Tshooj 412(g) ntawm Tsoom Fwv Teb Chaws Khoom Noj, Tshuaj, thiab Tshuaj pleev ib ce.
5 Tsiaj Nqid thiab Pet Food
Vitamin B6 is an essential nutrient for all animal species and is a standard ingredient in complete and balanced pet foods. Feed grade (>99% purity) yog siv rau hauv mash feed, pelleted feed, expanded feed, and extruded feed for swine, poultry, ruminants, aquaculture, and companion animal. Kev noj ntau npaum li cas ntawm 3-10 mg / kg ntawm pub nyob ntawm hom.
6 Cell Culture thiab Biotechnology tshawb fawb
High-purity vitamin B6 (Ntau dua lossis sib npaug li 98%) yog siv hauv cov kab lis kev cai ntawm cov tsiaj, cov tshuaj microbiological, thiab fermentation media rau kev tshawb fawb.
7 Tshuaj pleev ib ce and Kev Kho Tus Kheej
Pyridoxine hydrochloride tau muab tso rau hauv cov tshuaj tiv thaiv- cov tshuaj tiv thaiv kev laus, tshuaj pleev, cov khoom siv tawv nqaij, thiab cov qauv plaub hau rau nws cov tawv nqaij-nourishing zog, txhawb cov tawv nqaij noj qab haus huv thiab txo cov cim ntawm kev laus.
Cov lus nug nquag nug (FAQ)
Q: Dab tsi yog qhov txawv ntawm pyridoxine hydrochloride thiab lwm hom vitamin B6?
A: Vitamin B6 yog hais txog ib pab pawg ntawm rau dej- cov khoom sib txuas, suav nrog pyridoxal (PL), pyridoxamine (PM), pyridoxine (PN), thiab lawv 5'-phosphates. Pyridoxine hydrochloride yog hluavtaws, feem ntau ruaj khov daim ntawv ntawm vitamin B6, dav siv nyob rau hauv cov tshuaj thiab zaub mov fortification vim hais tias nws tseem muaj zog rau xyoo nyob rau hauv zoo cia. Lub cev hloov pauv pyridoxine rau hauv cov nquag coenzyme pyridoxal 5'-phosphate (PLP), uas koom nrog cov tshuaj lom neeg biochemical. Pyridoxine hydrochloride yog qhov zoo dua rau kev siv ntau vim nws txoj kev ruaj ntseg, dej solubility, thiab nqi-zoo.
Q: Cov khoom no puas ua raws li kev cai thoob ntiaj teb cov zaub mov thiab ntxiv cov cai?
A: Yog. Peb Pyridoxine Hydrochloride hmoov yog tsim nyob rau hauv GMP-certified chaw.
Q: Kuv puas tuaj yeem tau txais ib qho qauv ua ntej muab qhov kev txiav txim ntau?
A: Yog. Peb muab cov qauv kuaj ntsuas (feem ntau yog 10-100g) rau kev soj ntsuam zoo, kev tsim qauv, thiab kev tshuaj ntsuam xyuas. Cov qauv xaj tuaj yeem xa tuaj tsis pub dhau 3-5 hnub ua haujlwm.
Q: Cov kev xaiv ntim khoom twg muaj?
A: Aluminium ntawv ci hnab (1-5 kg), ntim yas nruas (10-25 kg), fiber ntau nruas (25-50 kg), thiab customized ntim raws li kev thov.
Q: Cov ntaub ntawv dab tsi koj muab rau txhua qhov khoom xa tuaj?
A: Txhua qhov khoom xa tuaj suav nrog Daim Ntawv Pov Thawj Kev Ntsuam Xyuas (COA), Daim Ntawv Qhia Cov Ntaub Ntawv (TDS), Daim Ntawv Qhia Txog Kev Nyab Xeeb (SDS), Cov Ntaub Ntawv Kev Nyab Xeeb Cov Ntaub Ntawv (MSDS), daim ntawv qhia tshwj xeeb, thiab lwm yam.
Q: Koj lub sijhawm ua haujlwm rau kev txiav txim ntau yog dab tsi?
A: Rau cov qauv txiav txim ntau (Ntau dua lossis sib npaug rau 25 kg), lub sijhawm ua haujlwm feem ntau yog 10-15 hnub ua haujlwm tom qab kev txiav txim pom zoo thiab them nyiaj.
Q: Koj puas muab kev cai particle loj los yog encapsulation kev pab cuam?
A: Yog. Peb muab kev cai micronization, microencapsulation, kev cai premixes nrog lwm cov vitamins thiab minerals, thiab tshuaj tsuag-qhuav formulations. Thov hu rau peb pab neeg technical los tham txog koj cov kev xav tau tshwj xeeb.
Q: Yuav ua li cas Vitamin B6 industrially tsim?
A: Vitamin B6 (pyridoxine hydrochloride) feem ntau yog tsim los ntawm cov tshuaj synthesis, vim tib neeg thiab cov kab mob siab dua tsis tuaj yeem ua rau nws. Txawm hais tias cov poov xab thiab cov kab mob tuaj yeem tsim cov vitamin B6, kev tsim khoom lag luam tso siab rau cov txheej txheem hluavtaws kom ua tiav siab purity thiab nqi-zoo rau cov khoom siv thoob ntiaj teb. Cov khoom yog ces purified, crystallized, thiab kuaj kom tau raws li pharmacopeia specifications ua ntej tso tawm.
Vim li cas thiaj xaiv peb?
Koj tus kws tshaj lij kev tsim khoom & Sourcing tus khub
Peb yog ntau tshaj li tus neeg muag khoom - peb yog cov khoom lag luam sib txuas ua ke rau siab - cov khoom xyaw zoo, cov qauv kev cai, thiab cov khoom tiav thoob plaws ntau qhov kev lag luam.
Cov kws tshaj lij
Nrog rau ntau xyoo ntawm kev paub hauv cov nroj tsuag extracts, khoom noj khoom haus additives, cosmetic raw cov ntaub ntawv, thiab cov khoom noj khoom haus, peb pab neeg coj cov kev txawj ntse txawj ntse thiab kev ua lag luam kev pom zoo rau txhua qhov kev koom tes.
01
Ntau Yam Khoom Muag
Peb muab ntau yam khoom lag luam nrog rau cov khoom noj ntxiv, cov khoom siv cog qoob loo, txiv hmab txiv ntoo & zaub hmoov, cov khoom siv tshuaj pleev ib ce, thiab cov khoom xyaw ua zaub mov.
02
Ib -Stop Shop
Raw Khoom:High -cov khoom xyaw purity rau zaub mov, dej haus, ntxiv, thiab kev siv tshuaj pleev ib ce.
Cov khoom tiav:Hauv -tsev tsim cov tshuaj ntsiav, mos gels, gummies, kua tee, thiab hmoov sib tov.
03
Kev pabcuam OEM / ODM / OBM
Label Design & Ntim:Kev cai branding tailored rau koj lub hom phiaj ua lag luam.
Formulation & R & D:Cov kws tshaj lij kev txhawb nqa los tsim cov kev cai sib xyaw, cov qauv tsim muaj, thiab cov khoom siv tshiab.
Ntiaj teb no Logistics:Txhim khu kev xa khoom, cov ntaub ntawv, thiab kev pabcuam kev lis kev cai.
04
Quality Assurance
Kev nruj nruj raws li GMP cov qauv thiab tag nrho cov kev cai pob tshab. Peb nyob twj ywm tam sim no nrog cov kev cai thoob ntiaj teb suav nrog FDA GRAS, EFSA, thiab lwm yam kev cai hauv cheeb tsam kom ntseeg tau tias koj cov khoom ua tau raws li cov qauv kev nyab xeeb siab tshaj plaws thiab ua raws.
05
Ua tam sim no
Npaj los tsim nrog hwmPure Vitamin B6 hmoov?
- Thov ib daim ntawv los yog qauv
- Thov Cov Ntaub Ntawv: COA, TDS, SDS, lossis cov ntaub ntawv ua raws cai
- Kev txiav txim ntau & Daim ntawv cog lus Manufacturing: Nug txog lub sij hawm luv nqi ntim thiab ntev - daim ntawv cog lus muab khoom.
- Qauv Cai: Lab- cov qauv ntsuas (10–100g) muaj rau kev tsim kho thiab kev ntsuas kom zoo.
Thov hu rau peb ntawmella.zhang@huilinbio-tech.com.
Cov ntaub ntawv
Cim npe nrov: vitamin b6 (pyridoxine hydrochloride) hmoov, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, ntuj, zoo, Tshuag, kev muag
