Taw qhia
D-Malic Acidyog qhov tsis yog -naturally tshwm sim D-enantiomer ntawm malic acid. Thaum nws cov L-isomer yog ubiquitous nyob rau hauv cov xwm (xws li, nyob rau hauv apples) thiab ib tug central metabolite nyob rau hauv tib neeg lub cev, D-malic acid yog feem ntau tsim synthetically. Qhov sib txawv stereochemistry no muab nws cov khoom tshwj xeeb thiab cov ntawv thov piv rau L- daim ntawv, ua rau nws muaj txiaj ntsig chiral tsev thaiv hauv kev tshawb fawb qib siab, tshwj xeeb tshuaj synthesis, thiab xaiv cov ntawv thov kev lag luam uas yuav tsum muaj qhov tshwj xeeb molecular configuration.
Physical & Chemical Parameters
| Parameter | Specification / Tus nqi | Sau ntawv / Reference |
|---|---|---|
| Melting Point | 100 - 104 degree | |
| Boiling Point | ~ 306 degree | |
| Flash Point | 153.4 hli | |
| Qhov ntom | 1.595 g / cm³ | |
| Solubility hauv dej | Soluble heev.Soluble hauv methanol, ethanol, thiab acetone. Xyaum insoluble hauv benzene. | |
| pH (1% daws) | Kwv yees li . 3.0 - 4.0 | Cov yam ntxwv acidic khoom. |
| Enthalpy ntawm Fusion (ΔfusH) | 23.01 kJ/mol | Thermodynamic cov ntaub ntawv ntawm 376 K. |
Mechanism ntawm Action
Lub luag haujlwm lom neeg thiab cov txheej txheem ntawm D-malic acid txawv ntawm nws cov L- counterpart, uas yog qhov tseem ceeb nruab nrab ntawm cov tsiaj nyeg.Tricarboxylic acid (TCA) lub voj voog.
- Qhov txawv ntawm L-Malic Acid:Hauv feem ntau cov kab mob aerobic, suav nrog tib neeg, cov enzymes ntawm TCA lub voj voog (xws li malate dehydrogenase, fumarase) yog cov stereospecific thiab xaiv metabolize.L-malic acidlos tsim lub zog (ATP). D-malic acid yogtsis yog substrate rau cov thawj mammalian metabolic txoj kev.
- Hom phiaj thiab hom kev ua:Nws lub ntsiab tseem ceeb nyob rau hauv nws lub luag hauj lwm raws li ib tugchiral synthonthiab substrate rau cov txheej txheem microbial lossis enzymatic. Piv txwv li, qee yam kab mob nyiamEscherichia colimuaj cov enzymes inducible uas muaj peev xwm metabolizing D-malic acid. Hauv kev tshawb fawb, nws cuam tshuam nrog cov enzymes tshwj xeeb uas tuaj yeem siv D- daim ntawv, cuam tshuam rau txoj hauv kev biochemical txawv ntawm lub voj voog canonical TCA.
- Metabolic Pathways:Txawm hais tias tsis yog ib feem ntawm tib neeg cov metabolism hauv nruab nrab, D-malic acid tuaj yeem koom nrog lwm cov ntsiab lus metabolic, xws lirumen fermentationnyob rau hauv cov tsiaj nyeg, qhov twg nws tau kawm txog nws lub peev xwm los hloov microbial fermentation profiles.
Cov txiaj ntsig tseem ceeb & Kev ua tau zoo
- High Chiral Purity:Muab ib qho zoo-txhais tseg, ib leeg-enantiomer pib cov khoom siv rau asymmetric synthesis thiab stereochemical kev tshawb fawb.
- Kev tshawb fawb tshwj xeeb:Ua haujlwm raws li qhov zoo tagnrhokev tswj tsis zoo lossis tus neeg sawv cev sib pivHauv kev sim tshuaj lom neeg tshawb xyuas cov haujlwm stereospecific ntawm L-malic acid hauv cov metabolism, teeb liab, thiab enzymology.
- Cov khoom xyaw tshwj xeeb ua haujlwm:Hauv tshuaj pleev ib ce, nws ua haujlwm me mealpha{0}}Hydroxy acid (AHA), pab txhawb rau cov tawv nqaij exfoliation thiab moisturization, nrog rau kev sib cuam tshuam profile ntau dua li L- daim ntawv.
- Stability & Zoo:Synthetic ntau lawm ua kom zoo ib yam batch- mus rau -batch purity thiab zoo, tsis muaj tej yam ntuj tso variations.
Cov ntawv thov tseem ceeb
| Kev lag luam / teb | Piv txwv daim ntawv thov | Lub luag haujlwm ua haujlwm & Lub luag haujlwm |
|---|---|---|
| Biochemical & Pharmaceutical Research | Substrate rau kev kawm tshwj xeeb D-acid metabolizing enzymes; chiral intermediate nyob rau hauv synthesizing tshiab tshuaj tebchaw; tswj cov txheej txheem metabolic. | Leverages nws tsis yog -natural stereochemistry los soj ntsuam cov txheej txheem lom lom lossis tsim cov molecules nrog qhov xav tau kev teeb tsa spatial. |
| Tshuaj pleev ib ce & Kev kho tus kheej | Exfoliating tus neeg sawv cev hauv kev tiv thaiv - cov tshuaj pleev xim thiab cov tawv nqaij; pH adjuster thiab humectant nyob rau hauv daim tawv nqaij formulations. | Ua raws li AHA me me los txhawb cov tawv nqaij rov ua dua tshiab thiab txhim kho hydration. |
| Food Science (Kev Tshawb Fawb Txog Kev Tshawb Fawb) | Cov ntsiab lus ntawm kev tshawb fawb ntawm lwm cov acidulants; tshawb fawb txog nws cov teebmeem ntawm microbial fermentation (piv txwv li, hauv cov khoom siv mis los yog nqaij). | Nws qhov txawv saj profile thiab microbial kev sib cuam tshuam yog thaj chaw ntawm kev tshawb fawb siv, sib txawv ntawm cov zaub mov zoo sib xws -qib L- lossis DL- malic acid. |
| Kev tshawb nrhiav tsiaj txhu | Tshawb nrhiav raws li kev noj zaub mov ntxiv hauv kev tshawb fawb ruminant los hloov kho rumen fermentation thiab txo qis methane emissions. | Cov kev tshawb fawb qhia tias nws tuaj yeem hloov pauv rumen microbiome profile, txhawb kev sib txawv ntawm cov roj fatty acid ntau lawm. |
Daim Ntawv Ceeb Toom Tseem Ceeb:Thaum malic acid feem ntau (feem ntau raws li DL-sib tov) tau pom zoo raws li cov khoom noj ntxiv (piv txwv li, E 296 hauv EU, INS 296 hauv Suav teb) rau kev siv los ua cov tshuaj acidity nyob rau hauv ntau hom zaub mov, cov kev cai tshwj xeeb ntawm kev sib cais.D-enantiomerrau kev siv khoom noj ncaj qha tuaj yeem sib txawv raws li kev txiav txim siab thiab yuav tsum tau txheeb xyuas rau lub hom phiaj kev lag luam. Peb cov khoom muaj feem ntau rau kev tshawb fawb thiab kev lag luam synthesis lub hom phiaj.
FAQ: Cov lus nug nquag nug
Q: Dab tsi yog qhov txawv ntawm D-Malic Acid thiab L-Malic Acid?
A: Lawv yog stereoisomers (daim iav- duab molecules). L-Malic acid yog ntuj, koom nrog tib neeg lub zog metabolism (TCA lub voj voog), thiab muaj ntau hauv cov khoom noj. D-Malic acid yog hluavtaws, tsis metabolized ntawm tib neeg TCA lub voj voog, thiab yog siv rau nws cov khoom tshwj xeeb chiral hauv kev tshawb fawb thiab kev siv tshwj xeeb.
Q: Puas yog D-Malic Acid muaj kev nyab xeeb?
A: Thaum ua haujlwm raws li lub chaw soj nstuam lossis kev lag luam tshuaj siv cov kev ceev faj tsim nyog, nws muaj kev nyab xeeb. Nws feem ntau lees paub tias muaj kev nyab xeeb (GRAS) rau qee yam kev siv, tab sis nws tsis yog tsim rau tib neeg noj cov khoom ntxiv tshwj tsis yog tshwj xeeb tsim thiab pom zoo rau lub hom phiaj ntawd. Ib txwm xa mus rau Daim Ntawv Qhia Txog Kev Nyab Xeeb (SDS) rau kev coj ua kom raug.
Q: Puas tuaj yeem D-Malic Acid tuaj yeem siv los hloov ncaj qha rau L- lossis DL-Malic Acid hauv zaub mov?
A: Tsis ncaj qha. Vim nws txoj hmoo metabolic sib txawv thiab muaj peev xwm tswj tau qhov xwm txheej, nws yuav tsum tsis txhob suav tias yog ib qho kev hloov pauv ncaj qha hauv cov khoom noj uas pom zoo rau L- lossis DL- malic acid. Nws siv nyob rau hauv cov khoom noj khoom haus yuav tsum tau cais kev nyab xeeb thiab kev tswj xyuas.
Ua tam sim no
Txhawb nqa koj cov kev tshawb fawb thiab kev tsim khoom nrog peb cov khoom muaj kev ntseeg siab, siab -purityD-Malic Acid hmoov. Peb xyuas kom cov batch-rau-batch sib xws, cov ntaub ntawv dav dav (xws li CoA), thiab tag nrho traceability.
Hu rau peb pab neeg muag khoom hnub no rau:Tau txais kev sib twlus haisthiab kawm txog peb cov kev xaiv ntim tau yooj yim los ntawm grams mus rau ntau qhov ntau.
Thov hu rau peb ntawmella.zhang@huilinbio-tech.com.
Tsis lees paub: Cov khoom no yog npaj rau kev tshawb fawb thiab kev lag luam siv los ntawm cov kws tshaj lij. Nws yog lub luag haujlwm ntawm tus neeg yuav khoom kom ua raws li tag nrho cov kev cai hauv zos, lub tebchaws, thiab thoob ntiaj teb hais txog kev tuav, siv, thiab siv cov khoom no. Cov ntaub ntawv muab los ntawm no yog rau kev piav qhia nkaus xwb thiab tsis yog ib qho kev qhia tshwj xeeb lossis kev pom zoo rau kev siv tshwj xeeb.
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