Khoom taw qhia
Kojic acid dipalmitate hmoovyog ib qho tshiab whitening raw khoom ntawm lub khw. Nws yog ib qho derivative ntawm kojic acid. Vim nws txoj kev ruaj ntseg zoo, cov nyhuv whitening zoo, thiab tsis muaj qhov khaus ntawm daim tawv nqaij, nws tau dhau los ua qhov nrov tshaj plaws hauv kev lag luam whitening. Ib qho kev nyiam tshiab, Kojic acid, yog maj mam tshem tawm los ntawm kev ua lag luam vim nws tsis muaj kev ruaj ntseg thiab nyuaj hauv kev sib xyaw.
Hauv kev lag luam tshuaj pleev ib ce tam sim no, cov tshuaj pleev ib ce ua kom zoo nkauj nyob hauv ib nrab ntawm lub teb chaws, thiab cov ntaub ntawv ntxuav hniav dawb tau raug qhia tas li, yog li cov nyhuv ntawm cov tshuaj pleev ib ce ua kom zoo dua qub, muaj kev nyab xeeb, thiab tus nqi zoo. Cov tshooj hauv qab no txheeb xyuas qhov sib txawv ntawm kojic acid thiab kojic acid dipalmitate nyob rau hauv cov nqe lus ntawm lawv lub cev thiab tshuaj zog, stability, thiab whitening nyhuv. Cia kuv nthuav rau lawv.
1. Qhov sib txawv ntawm lub cev thiab tshuaj lom neeg
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Kojic acid |
Kojic acid dipalmitate |
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CAS Nr |
501-30-4 |
79725-98-7 |
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Cov mis mos molecular |
C6H6O4 |
C38H66O6 |
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Molecular Structure |
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Molecular hnyav |
142.11 g / mol |
618,93 g / mol |
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Lub cev thiab tshuaj muaj zog |
Dawb rau me ntsis daj crystalline hmoov, melting point yog 150 degree -154 degree |
Dawb crystalline hmoov, melting point 92-96 degree |
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Solubility |
Yooj yim soluble hauv dej, ethanol, ethyl acetate |
Insoluble hauv dej tab sis soluble hauv roj, propylene glycol |
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Compound kev ua tau zoo |
Vim muaj peev xwm hydrogen bonding nyob rau hauv nws cov qauv molecular, cov khoom no tsis sib xws nrog qee cov tshuaj pleev thaiv hnub organic thiab cov khoom khaws cia. |
Nws yog sib xws nrog feem ntau cov khoom xyaw kom zoo nkauj thiab tuaj yeem muab ntxiv rau cov khoom kom zoo nkauj ua ke nrog cov tshuaj pleev thaiv hnub. Nws yog roj soluble, thiab kojic acid dipalmitate yog yooj yim absorbed los ntawm daim tawv nqaij thaum ntxiv rau cream dua kojic acid. |
Kojic acid, metabolite ntawm Aspergillus oryae, tau pom thawj zaug hauv kev lag luam brewing. Tom qab ntawd, ib yam khoom uas muaj cov nyhuv whitening, kojic acid, tau pom nyob rau hauv cov kua ntses brewed los ntawm Aspergillus oryae. Nws cov txheej txheem ntau lawm yog raws li nram no: firstly inoculate Aspergillus oryzae nyob rau hauv ib tug kab lis kev cai nruab nrab ntawm cov piam thaj ntawm ib tug kub ntawm 30-32 degrees Celsius, thiab ces ferment rau 5-6 hnub kom tau ib tug crude khoom; Tom qab ntawd lim, mloog zoo, rho tawm, thiab lwm cov kauj ruam ntawm cov khoom ntuj, tom qab ntawd, nws raug kho nrog cov pa roj carbon activated, muab rho tawm thiab crystallized kom tau kojic acid.
Txij li kojic acid dipalmitate yog kojic acid derivative, nws cov txheej txheem tsim tawm kuj muaj qee yam cuam tshuam rau kojic acid. Cov kauj ruam tshwj xeeb yog thawj zaug sib tov palmitic acid thiab phosphorus trichloride kom tau palmitoyl chloride, thiab tom qab ntawd ntxiv kojic acid cov khoom tuaj yeem tau txais.
2. Hais txog kev ruaj ntseg
Kojic acid muaj cov txiaj ntsig zoo ntawm inhibiting tyrosinase kev ua haujlwm thiab kev tsim melanin. Nws yog ib qho khoom siv ua kom zoo nkauj zoo nkauj thiab tuaj yeem siv rau hauv cov tshuaj pleev ib ce kom tshem tawm cov freckles, hnub nyoog me me, cev xeeb tub, pigmentation, thiab lwm yam khoom.
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Kojic acid has an excellent cosmetic effect, but it is rarely used in products due to its instability. Its disadvantage is that it is susceptible to light and heat and quickly oxidizes in the air. In terms of color: it reacts with many metal ions, such as ferric ions, which will make the formulated skin whitening product gradually turn yellowish brown during use; from the PH value, when the PH value is >7, Thaum kojic acid siab tshaj 40 degree, nws yuav tsis ruaj khov, thiab thaum kawg, nws yuav tsis ruaj khov thaum kojic acid siab tshaj 40 degree, thiab ib tug cream uas muaj 1% kojic acid yuav tig daj thaum muab tso rau ntawm 45 degree rau plaub lub lis piam mus rau xim av.
Txawm li cas los xij, txij likojic acid dipalmitate hmoovtag nrho overcomes cov shortcomings ntawm kojic acid, nws muaj zoo heev stability nyob rau hauv formulation. Nyob rau tib lub sijhawm, nws yuav tsis tsim cov tshuaj tiv thaiv nrog lwm cov khoom xyaw hauv cov tshuaj pleev ib ce, thiab txo qhov nyuaj ntawm kev tsim. Nyob rau hauv cov txheej txheem tshuaj pleev ib ce, thaum cov roj theem yog rhuab mus rau 75 degree -85 degree, cov khoom yuav zoo melted rau hauv cov roj theem thiab ces emulsified, uas yog yooj yim rau kev npaj.
3. Qhov sib txawv ntawm ob qho tib si hauv cov nyhuv whitening
Raws li kev sim, cov nyhuv whitening ntawm kojic acid thiab kojic acid dipalmitate yog qhia hauv daim duab hauv qab no. Lub Y-axis nyob rau hauv daim duab sawv cev rau lub peev xwm nqus ntawm 475nm lub teeb yoj. Los ntawm kev kuaj xyuas cov xim ntawm ntau yam melanin intermediates, tyrosinase kev ua haujlwm tau tshwm sim. Lub x-axis yog lub sijhawm dhau los txij li thaum tyrosinase tau ntxiv rau qhov nruab nrab. Cov txiaj ntsig kev sim tau pom tias cov pab pawg ntawm cov kev sim uas ntxiv kojic acid rov qab tau nws txoj haujlwm tyrosinase ntawm 5 feeb, thaum pab pawg ntawm kev sim nrog kojic acid dipalmitate tsuas yog qeeb tyrosinase ntawm 12 feeb. Maj mam qhia nws lub zog. Tsis tas li ntawd, ob yam tshuaj no kuj tau kuaj xyuas cov neeg muaj kab mob pigmented. Cov txiaj ntsig tau pom tias qhov ua tau zoo ntawm kojic acid thiab kojic acid dipalmitate yog 60% -95% thiab 80%, feem.
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Nws tuaj yeem pom tias cov nyhuv whitening ntawm kojic acid dipalmitate zoo dua li ntawm kojic acid. Tsis tas li ntawd, txij li kojic acid dipalmitate muaj cov roj solubility zoo, nws tuaj yeem nqus tau yooj yim dua thiab siv los ntawm daim tawv nqaij, thiab nws kuj yog ib qho zoo heev moisturizing tus neeg saib xyuas.
Cov ntsiab lus ntawm kojic acid thiab kojic acid dipalmitate
Qhov chaw: kojic acid thiab kojic acid dipalmitate tuaj yeem muab rho tawm los ntawm cov nroj tsuag ntuj lossis hluavtaws. Kojic acid feem ntau muaj nyob hauv qee cov txiv hmab txiv ntoo, xws li blueberry thiab pomegranate, thiab kojic acid dipalmitate tau txais los ntawm cov tshuaj tiv thaiv ntawm kojic acid thiab palmitic acid.
Oxidation kuj: kojic acid thiab kojic acid dipalmitate muaj qee yam oxidation tsis kam. Lawv tuaj yeem pab tiv thaiv kev tsim cov dawb radicals thiab cov tshuaj tiv thaiv oxidation, thiab muaj lub luag haujlwm hauv kev tiv thaiv cov hlwb los ntawm kev puas tsuaj oxidative.
Daim ntawv thov: kojic acid thiab kojic acid dipalmitate muaj cov ntawv zoo sib xws hauv qee qhov chaw. Piv txwv li, lawv tuaj yeem siv rau hauv kev lag luam khoom noj khoom haus raws li cov khoom noj khoom haus ntxiv kom muaj kev nyab xeeb thiab txuag cov khoom noj.
Yuav tiv tauj peb li cas?
Peb lub tuam txhab muaj ntau xyoo ntawm kev muag khoom hauv kev lag luam cog extract, muaj ntau yam khoom zoo, thiab yog ib tus kws tshaj lijKojic acid dipalmitate hmoovtus neeg muag khoom. Dhau li ntawm, peb cov khoom yog ncaj qha los ntawm lub Hoobkas, tsis tsuas yog pheej yig tab sis kuj zoo. Peb lub tuam txhab muag cov khoom saum toj no, thiab yuav muaj kev txo nqi zoo yog tias koj yuav ntau ntau. Yog tias koj txaus siab, koj tuaj yeem tiv tauj peb.
Peb qhov kev sib cuag yog: ua ntej, tiv tauj peb los ntawm lub vev xaib thoob ntiaj teb lossis email; peb email yogella.zhang@huilinbio-tech.com ib; peb tus thawj tswj hwm tus account yuav teb sai li sai tau thaum koj pom cov xov xwm. Qhov thib ob, koj tuaj yeem mus ntsib Chav 706, Block B, Fengze Science, thiab Technology Park, No. 170 West Street, Yanta District, Xi'an City, Shaanxi Province.