Vinpocetine yog dab tsi?
Vinpocetine hmoovtseem hu ua vinvinethyl ester, Convirol, karan, ethyl apvinvinaminate, yog ib yam tshuaj uas muab rho tawm los ntawm vinca roseus thiab belongs rau indole alkaloids. Nws tau raug synthesized artificially. Vinpocetine yog dawb crystalline hmoov, tsis muaj ntxhiab thiab tsis qab. Soluble hauv chloroform lossis 96 feem pua ethanol, NW nyuam qhuav soluble hauv dej. Melting point 147-153 degree (decomposition). [ ]D20 ntxiv rau 114 degree (C=1, pyridine). UV siab tshaj plaws nqus (96 feem pua ethanol): 229,275,315 nm (ε 28,200, 1,200,7100). Mob toxicity LD50 nas, nas (mg/kg): 534,503 qhov ncauj; Intraperitoneal txhaj tshuaj; 58.7, 42.6 txhaj tshuaj. Clinically, nws tuaj yeem txhim kho ntau yam tsos mob tshwm sim los ntawm cerebral infarction sequelae, cerebral hemorrhage sequelae thiab cerebral arterial sclerosis.
Lub npe | Vinpocetine |
Suav alias | ChangchunXiding;(3Α,16 -ivoriene-14-carboxylate; |
English npe | Vinpocetine |
English alis | Eburnamenine-14-carboxylic acid ethyl ester; (3,16)-Eburnamenine-14-carboxylic acid ethyl ester |
CAS Nr | 42971-09-5 |
MDL num | TIAB SA 00211233 |
RTECS tus lej | JW4792000 |
EINECS tus lej | 256-028-0 |
PubChem num | 24278182 |
Cov mis mos molecular | C22H26N2O2 |
Cov txiaj ntsig Vinpocetine
1. Ua kom cov ntshav cerebral txaus;
2. Txhawb nqa thiab siv cov piam thaj thiab cov pa oxygen hauv lub hlwb, nce ATP, thiab txo qis kev tsim cov lactic acid thaum lub sij hawm ischemia thiab hypoxia;
3. Tiv thaiv kom txhob muaj kuab lom tuag los ntawm lub hlwb excitation (ntau dhau receptor excitation los ntawm amino acids los ntawm Xing Ga I);
4. Txo kev puas hlwb hypoxia thiab tiv thaiv neurons;
5 Txhim kho txoj haujlwm ntawm dopaminergic, serotonergic thiab norepinephrinic qab haus huv;
6 Vinpocetine hmoovtuaj yeem tiv thaiv ischemic puas rau lub hlwb, daim siab, cov leeg nqaij thiab lwm yam;
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7 tshem tawm cov dawb radicals thiab tiv thaiv lipid peroxidation;
8. Txhim khu kev nco mus ntev thiab luv luv;
9. Ua kom ceev ceev
10. Txo cov senile hlwb tsis ua hauj lwm;
11. Tshem tawm ntawm atherosclerotic plaque;
12. Ua kom lub plawv tso zis thiab cov ntshav txaus rau txhua lub cev;
13 Txhawb vasodilation thiab txhim kho cov ntshav ncig, tab sis tsis tshua muaj kev cuam tshuam rau cov ntshav peripheral;
14 txhim kho qhov muaj pes tsawg leeg ntawm lipoprotein hauv cov ntshav; txhim kho cov ntshav liab deformability

vinpocetine ua haujlwm li cas?
1. Department of Neurology: ntau yam kab mob cerebrovascular thiab lawv cov sequelae, thiab lwm yam.
2, kab mob plawv: kab mob plawv, arteriosclerosis thiab ntshav viscosity txawv txav, thiab lwm yam.
3, ophthalmology: ntau yam fundus ntshav ncig los ntawm qhov muag tsis pom kev, thiab lwm yam.
4. Otorhinonuclear Department: hnov kev puas tsuaj, tinnitus, vestibular dysfunction, thiab lwm yam.
5. Neurosurgery: rov kho lub hlwb ua haujlwm tom qab ntau yam kev ua haujlwm craniocerebral.
Cov lus qhia
Vinpocetine ceeb toom
Tsis muaj kev cuam tshuam nrog vinpocetine tau pom hauv kev sim tshuaj thaum vinpocetine tau ua ke nrog beta blockers (xws li cloralol, indololol) clopamine, glibenluide, digoxin, acetocoumarin, lossis hydrochlorothiazide.
Thaum vinpocetine ua ke nrog methyldopa, nws cov nyhuv antihypertensive yog qee zaus txhim kho me ntsis, yog li ntshav siab yuav tsum tau saib xyuas thaum ua ke.
Txawm hais tias tsis muaj kev cuam tshuam ntawm vinpocetine thiab cov kab mob hauv lub paj hlwb, cov tshuaj antiarrhythmic thiab anticoagulants tau pom nyob rau hauv cov kev tshawb fawb soj ntsuam, nws tseem pom zoo kom ua tib zoo saib xyuas kev sib xyaw ntawm cov tshuaj.
Cov poj niam cev xeeb tub, cov laus thiab cov poj niam laus
Cov poj niam cev xeeb tub thiab cov poj niam lactating raug txwv.
Poj niam cev xeeb tub
Vinpocetine tuaj yeem hla cov placenta, tab sis nws cov concentration hauv cov placenta thiab fetus yog qis dua li hauv cov poj niam cev xeeb tub cov ntshav. Tsis muaj teratogenic los yog fetal toxic cuam tshuam. Hauv kev tshawb fawb tsiaj, kev siv tshuaj ntau ntau tuaj yeem ua rau cov ntshav tso placental thiab nchuav menyuam hauv qee cov tsiaj, tejzaum nws tshwm sim los ntawm cov ntshav placental ntau ntxiv.
Poj niam lactating
Vinpocetine tuaj yeem tso rau hauv cov mis nyuj. Kev ntsuam xyuas radiolabelling tau pom tias muaj hluav taws xob hauv cov mis nyuj yog 10 npaug ntau dua hauv cov ntshav niam. Cov mis nyuj uas tsim nyob rau hauv ib teev muaj 0.25 feem pua ntawm cov koob tshuaj. Vim hais tias cov tshuaj muaj nyob rau hauv cov kua mis secreted, tsis muaj cov ntaub ntawv txhim khu kev qha ntawm nws cov teebmeem ntawm cov menyuam mos, yog li cov poj niam pub niam mis yuav tsum zam.
Tshuaj rau cov laus
Cov lus qhia ntawm cov khoom no yog feem ntau yog rau cov neeg laus, yog li cov ntsiab lus tseem ceeb ntawm phau ntawv yog rau cov neeg laus, thov saib cov ntsiab lus tseem ceeb.
Yuav tiv tauj peb li cas?
Peb yog ib lub tuam txhab nrog ntau xyoo ntawm kev muag khoom nyob rau hauv cov nroj tsuag extract kev lag luam. Tom qab xyoo ntawm kev ua haujlwm, peb muaj ntau yam khoom, xws li txiv hmab txiv ntoo thiab zaub hmoov, tshuaj pleev ib ce, ntsiav tshuaj khoom qab zib thiab lwm yam khoom. Peb yog cov kws tshaj lij cov khoom siv raw khoom. Tam sim no, peb lub tuam txhab muag pheej yigVinpocetine hmoovnyob rau hauv tej, uas yog dav siv nyob rau hauv cov khoom kho mob, tshuaj, tshuaj pleev ib ce thiab lwm yam teb. Cov uas yuav tsum tau ua cov khoom kho mob tuaj yeem yuav cov khoom siv raw no. Lub caij no, raws li peb cov khoom muag ncaj qha los ntawm cov chaw tsim khoom, qhov zoo ntawm peb cov khoom tuaj yeem paub tseeb.
Yog tias koj xav yuav lossis txaus siab rau nws, koj tuaj yeem xa email rau peb qhov chaw ua haujlwm emailella.zhang@huilinbio-tech.com iblos ntawm lub vev xaib thoob ntiaj teb. Peb yuav teb koj sai li sai tau thaum koj pom cov lus. Tsis tas li ntawd, koj tuaj yeem mus saib qhov chaw offline. Peb lub tuam txhab nyob hauv Chav 706, Tsev B, Fengze Science Park, No. 170, West Street, Yanta District, Xi 'an City, Shaanxi Province. Zoo siab txais tos koj tuaj xyuas.







