Puas yog vinpocetine hmoov nce dopamine?

Taw qhia txog vinpocetine

Vinpocetine hmoov yog ib qho khoom muaj txiaj ntsig tau muab rho tawm los ntawm cov nroj tsuag. Nws tsuas yog kho kiv taub hau, kiv taub hau, mob taub hau, tsis nco qab, hemiplegia thiab aphasia tshwm sim los ntawm cerebral infarction sequelae, cerebral hemorrhage sequelae thiab cerebral arterial sclerosis. Nws yog cerebral vascular dilator thiab muaj qee yam tshuaj tiv thaiv coagulant.

Feem ntau cov kab mob cerebrovascular yog vascular blockage tom qab thrombosis, uas tuaj yeem ua rau cov hlab ntsha txhaws tsis muaj zog dua, thiab tuaj yeem kho cov kab mob cerebrovascular. Nws tuaj yeem txhim kho lub hlwb cov ntshav khiav los kho kiv taub hau los ntawm cov kab mob cerebrovascular, txo tib neeg cov ntshav viscosity, txhim kho cov ntshav txaus thiab microcirculation, txhawb nqa cov as-ham hauv lub hlwb, txo cov hlwb oxygen noj thiab txhim kho lub hlwb metabolism.

Cov txiaj ntsig vinpocetine yog dab tsi?

1.Inhibition ntawm calcium-dependent phosphodiesterase kev ua ub no tuaj yeem ua rau cov ntsiab lus cAMP hauv cov nqaij ntshiv ntawm cov leeg nqaij, yog li ua kom cov leeg nqaij du thiab ua rau cov hlab ntsha hauv hlwb. Ua kom cov ntshav cerebral ntws, los ntawm inhibiting Ca2 ntxiv rau kev ua haujlwm ntawm phosphodiesterase, ua kom cov nyhuv ntawm cyclic guanosine, xaiv so ntawm cov leeg nqaij, ua kom cov ntshav txaus; Txhim kho cov ntshav khiav thiab microcirculation los ntawm kev txhim kho cov deformability ntawm cov qe ntshav liab, txo cov ntshav viscosity thiab inhibiting platelet aggregation.

2. Txhim kho erythrocyte deformability, txo cov ntshav viscosity, inhibit platelet aggregation, yog li txhim kho cov ntshav mus thiab microcirculation. Txhim kho lub hlwb metabolism: nce cov pa oxygen ntawm lub hlwb, txhawb nqa cov piam thaj hauv cov ntaub so ntswg hauv hlwb, txhawb cov metabolism hauv kev hloov pauv ntawm monoamine hauv lub hlwb, inhibit qhov nce ntawm lactic acid metabolism hauv lub hlwb ischemic, nce cov ntsiab lus ntawm ATP, thiab nce qib oxygen dissociation ntawm hemoglobin

3. Vinpocetine hmoovua tau Txhawb nqa cov piam thaj hauv cov ntaub so ntswg ntawm lub hlwb thiab txhawb cov metabolic kev hloov pauv ntawm monoamine hauv hlwb. Ua kom muaj peev xwm tiv thaiv hypoxia ntawm lub hlwb, inhibit qhov tshwm sim ntawm ischemic cerebral vasospasm thiab tsim cov lipid peroxide. Qhov ncauj nqus tau zoo,

4. Thaum lub sij hawm cerebral ischemia, nws muaj peev xwm inhibit qhov nce ntawm lactic acid nyob rau hauv lub hlwb, nce cov ntsiab lus ntawm ATP, inhibit zus tau tej cov lipid peroxide nyob rau hauv lub hlwb, ncua lub sij hawm tshwm sim ntawm cerebral ischemia spasm, yog li nws muaj cov nyhuv ntawm kev txhim kho. lub hlwb metabolism thiab tiv thaiv lub hlwb ua haujlwm.

5. Nws yog metabolized rau hauv aportovinylamine acid hauv lub cev. Kev tshem tawm plasma ib nrab-lub neej yog li 1 teev. Tom qab kev tswj hwm tas li rau 4 lub lis piam, tsis muaj kev txuam nrog hauv lub cev. Kev kho mob rau cerebral infarction sequelae, cerebral hemorrhage sequelae, cerebral arteriosclerosis, cerebral vasospasm, cerebral endoarteritis tshwm sim los ntawm vertigo, tinnitus, mob taub hau, kiv taub hau, limbness, incontinence thiab lwm yam kev kho mob kev puas siab puas ntsws manifestions, as well as depression, . Kev paub txog kev kho mob tau pom tias nws muaj txiaj ntsig tsis hais qhov ntev ntawm tus kab mob thiab seb cov tsos mob puas kho

Yuav ua li cas txheeb xyuas vinpocetine?

(1) Noj li ntawm 0.5mg ntawm cov khoom no thiab ntxiv 2 mus rau 3 tee ntawm 1 feem pua ​​ammonium cerium sulfate phosphoric acid tov kom nws tshwm tsaus ntsuab.

(2) Siv cov khoom no thiab ntxiv methanol los ua cov tshuaj uas muaj 10ug ib 1ml. Qhov siab tshaj plaws nqus ntawm 229nm, 274nm thiab 314nm wavelength tau txiav txim siab los ntawm spectrophotometric (Nplooj 24 ntawm Cov Ntawv Ntxiv ntawm Ntu II ntawm Suav Pharmacopoeia, 1990 Edition), thiab qhov nqus ntawm 274nm wavelength yog li ntawm 0.34.

(3) Cov qauv infrared lub teeb haum ntawm cov khoom no yuav tsum ua raws li cov khoom siv.

Vinpocetine txaus ntshai

1. Kev ua xua: Qee zaum tuaj yeem tshwm pob liab liab, qee zaus urticaria, khaus thiab lwm yam kev tsis haum tshuaj, yog tias cov tsos mob no yuav tsum tau nres.

2. Psycho-nervous system: qee zaum mob taub hau, hnyav lub taub hau, vertigo, pw tsaug zog qee zaus, sab limb loog.

3. Kev zom zaub mov: qee zaum xeev siab, ntuav, kuj qee zaum tshwm sim tsis qab los noj mov, mob plab, raws plab thiab lwm yam tsos mob.

4. Cov kab mob hauv lub cev: qee zaum lub ntsej muag tawm, kiv taub hau thiab lwm yam tsos mob, qee zaum pom hypotension, tachycardia thiab lwm yam tsos mob.

5. Ntshav: Qee zaum leukopenia tuaj yeem tshwm sim.

6. Lub siab: Qee zaum nce transaminase, qee zaus nce alkaline phosphatase thiab jaundice tuaj yeem pom.

7.Kidney: Qee zaus cov ntshav urea nitrogen tuaj yeem tshwm sim.

Yuav tiv tauj peb li cas?

Peb lub tuam txhab yog cov kws tshaj lij ntawm cov khoom siv raw khoom ib nrab, suav nrog cov nroj tsuag extract, txiv hmab txiv ntoo thiab zaub hmoov, tshuaj pleev ib ce, ntsiav tshuaj khoom qab zib thiab lwm yam khoom; Peb cov khoom tau muab ncaj qha los ntawm cov chaw tsim khoom, yog li tus nqi yog qhov zoo heev, thiab qhov zoo yog lav, yog li koj tuaj yeem so assured mus yuav. Tam sim no, peb lub tuam txhab muag khoom zooVinpocetine hmoov, uas yog cov khoom siv zoo tshaj plaws rau cov khoom kho mob, tshuaj, kev tu tawv nqaij thiab lwm yam khoom.

Yog tias koj txaus siab rau cov khoom no thiab xav paub ntau ntxiv txog nws, koj tuaj yeem sab laj nrog peb tus thawj tswj hwm tus account los ntawm thoob ntiaj teb lub vev xaib lossis email, peb tus email chaw nyob yogella.zhang@huilinbio-tech.com ib;Peb lub Hoobkas nyob hauv Chav 706, Tsev B, Fengze Science Park, No.170 West Street, Yanta District, Xi 'an City, Shaanxi Province.