Cov tshuaj Vincamine Powder siv rau dab tsi?

Kev piav qhia ntawm vincamine

Vincamine hmoov(vincamine) yog ib qho ntawm cov alkaloids tseem ceeb hauv Vincamine. Nws yog cov hmoov dawb uas yog soluble hauv acidic tov. Nws yog pob zeb dawb-khoom alkaloid hauv monoterpene indole alkaloids. Nyob rau hauv 1953, Schlittle thiab Furlenmeier cais Chemicalbook los ntawm V. mainor. Xyoo 1962, Trojanek, Mokry, Clauder thiab al txiav txim siab nws cov qauv tshuaj. Xyoo 1968, Trojanek, Blaha et al. txiav txim siab qhov kev teeb tsa spatial ntawm vincamines. Cov qauv ntawm ntuj Changchun amine yog dextral, thiab cov hluavtaws Changchun amine yog haiv neeg. Rau qee qhov, Changchun amine muaj lub luag haujlwm ntawm kev tswj lub hlwb ncig, tswj cov hlab ntsha homeostasis, tiv thaiv paj hlwb thiab tiv thaiv oxidation.

Vincamine mechanism ntawm kev txiav txim

1. Kev kho cov kab mob ischemic plawv thiab cerebrovascular: vincristine tsis muaj kev cuam tshuam rau lub hlwb cov ntshav, tab sis txo qis cov cheeb tsam ischemic thiab txhim kho cov neeg mob cov qhab nia xeem. Vinamine tuaj yeem pom tseeb txhim kho cov tsos mob ntawm cov neeg mob uas muaj mob ischemic plawv thiab encephalopathy, cov nyhuv curative txaus siab, tab sis cov nyhuv ntev yuav tsum tau soj ntsuam ntxiv. Cov kev tshawb fawb tsis ntev los no tau pom tias vincristine tau tswj cov teebmeem ntawm cov hlab ntshav siab, lub plawv tawm thiab lub plawv dhia. Vinamine yog cerebrovascular dilator nrog siab lipid solubility thiab nqus tau yooj yim. Los ntawm cov hlab ntsha-hlwb barrier, nws tuaj yeem tswj lossis kho cov hlab ntsha ntawm lub cev, rov ua kom cov ntshav ntws zoo hauv thaj chaw ischemic, txhim kho kev siv cov ntshav oxygen, txhim kho cov metabolism hauv ischemic cov ntaub so ntswg, tiv thaiv neurons, thiab lwm yam.

2. Txhim kho koj lub cim xeeb: Vinamine (1 mg / kg) thiab piracetam (300 mg / kg) ob qho tib si nce tus txheeb ze thiab qhov tseem ceeb ntawm kev pw tsaug zog nrog me ntsis cuam tshuam rau qeeb yoj thiab tag nrho pw tsaug zog, tab sis cov nyhuv stimulant ntawm kev pw tsaug zog nrog pw tsaug zog. txhim khu kev nco. Vinamine muaj cov txiaj ntsig zoo rau Alzheimer's disease, uas tuaj yeem txhim kho cov neeg mob lub cev muaj peev xwm, kev nco thiab kev txawj ntse. Changchun amine tuaj yeem nce tus txheeb ze lossis tag nrho ntawm kev pw tsaug zog heterogeneous, tab sis muaj kev cuam tshuam me ntsis ntawm kev pw tsaug zog qeeb thiab tag nrho pw tsaug zog.

3. Vincamine hmoovmuaj peev xwm kho dementia: Kev kho mob ntawm thawj degenerative thiab vascular dementia nrog vinvinamine. Thaum lub sijhawm 12 lub lis piam ntawm kev kho ob qhov muag tsis pom kev, cov neeg mob kho nrog vinamine ntawm 30 mg txhua hnub lossis qhov sib npaug ntawm cov placebo tau pom cov qhab nia ua tau zoo dua ntawm Texas-based Clinical Assessment Scale for Geriatrics (SCAG) thiab Short-term Cognitive Ability Test (SK. T) tshaj pawg tswj.

4. Txhim kho qhov muag pom kev: Vinamine muaj txiaj ntsig zoo rau kev rov ua haujlwm ntawm cov neuronal tom qab retinal contusion. Kev txhaj tshuaj Vinamine muaj cov nyhuv curative ntawm qhov muag ischemic lesions, thiab kev txhim kho qib ntawm lub zeem muag, thaj chaw ntawm lub zeem muag thiab fundus yog pom tseeb zoo dua li ntawm Torazolin txhaj ib leeg, nrog tsawg dua kev phiv thiab pom tseeb curative nyhuv ntawm thawj ischemic optic paj hlwb retinochoroidal lesions. Vinamine tuaj yeem txhim kho thiab txhawb cov ntshav ncig, nce adenosine kev ua haujlwm los ntawm inhibiting adenosine uptake, txhawb cov paj hlwb kev ua haujlwm rov qab thiab paj hlwb rov tsim dua tshiab, thiab txhim kho kev pom kev zoo.

5. Lwm yam nqi tshuaj:

Cov teebmeem physiological ntawm vinamine nyob rau thaj tsam hippocampal CA1 ntawm lub hlwb tau kawm. Tom qab kev txhaj tshuaj tas li ntawm 100 mmol / L-1 vinamine rau 5 min, tom qab-tonic thiab kev txhim kho ntev ntev uas tau tshwm sim los ntawm kev rov ua kom lub paj hlwb ntawm Schaffer-commissural tuaj yeem txo qis lossis txawm tias tag nrho.

Txoj kev npaj ntawm vincamine

Ib txoj kev npaj rau Changchun amine muaj cov kauj ruam hauv qab no:

1) Kev npaj ntawm bonin: nyob rau hauv roj av ether, concentrated ammonia dej yog siv los dissociate bonin hydrochloride, thiab ces acid ntsev tov yog ntxiv kom tshem tawm cov seem ammonia dej. Tom qab cov tshuaj tiv thaiv ua tiav, cov kua tau muab faib, cov txheej dej tau muab rho tawm nrog roj av ether, cov txheej txheem organic yog ua ke, cov txheej txheem organic qhuav nrog desiccant thiab lim, thiab cov lim dej yog distilled nyob rau hauv siab kom tau txais bonin;

2) Kev npaj ntawm Longspring Manfermin: tabonine tau nyob rau hauv kauj ruam (1) yog yaj nyob rau hauv cov organic hnyav, thiab cov tshuaj tiv thaiv yog nqa tawm ntawm ib tug tej yam kub thiab txias los ntawm ntxiv Pd / C, hydrogen cua thiab atmospheric siab nyob rau hauv stirring. TLC tau siv los saib xyuas qhov kawg ntawm cov tshuaj tiv thaiv, lim tau lim, thiab cov filtrate tau distilled nyob rau hauv lub tshuab nqus tsev siab kom tau Longspring Manfermin

3) Kev npaj ntawm mono peroxy maleic acid: N, n-dimethylformamide tau yaj los ntawm kev ntxiv Chemicalbook anhydride ntawm maleic acid, thiab 30% hydrogen peroxide tau ntxiv rau qhov sib tov. Tom qab drips, cov tshuaj tiv thaiv yog nqa tawm. Tom qab cov tshuaj tiv thaiv tiav lawm, qhov ntsuas kub tau qis dua thiab diluted nrog txias methanol rau cia.

1) Kev npaj ntawm Changchun amine: Tom qab txias, ib qho nyiaj ntawm mono peroxymaleic acid tau nyob rau hauv kauj ruam (2) tau ntxiv rau cov tshuaj. Tom qab ib lub sij hawm ntawm oxidation cov tshuaj tiv thaiv, ib qho nyiaj ntawm mono peroxymaleic acid tau ntxiv rau cov tshuaj, thiab cov tshuaj tiv thaiv oxidation tau txuas ntxiv mus rau lub sijhawm. Tom qab cov tshuaj tiv thaiv tiav lawm, cov tshuaj txo tus neeg sawv cev tau ntxiv rau cov hmoov txhuv nplej siab KI daim ntawv xeem yam tsis hloov xim, thiab cov tshuaj tiv thaiv rov qab tau ua tiav ntawm qhov kub thiab txias. Tom qab cov tshuaj tiv thaiv tiav lawm, qhov kub poob mus rau 20-30 degree , thiab ib qho dej thiab cov concentrated ammonia ntxiv los kho cov pH rau qee qhov ntau. Tom qab ntawd, qhov kub poob mus rau crystallization thiab pom. Tom qab lub ncuav mog qab zib lim tau ntxuav nrog methanol thiab dej, lub pulp yog pulp nrog dej ntawm ib qho kub.

Cov txiaj ntsig ntawm vinblastine hmoov

Cov huab cua zoo heev: Vinyl amine hmoov tuaj yeem muab cov huab cua zoo tiv thaiv, yog li cov txheej txheem tuaj yeem khaws cov xim ci thiab du nto rau lub sijhawm ntev, thiab nws tsis yooj yim rau eroded los ntawm ultraviolet rays thiab oxidation.
Kev tiv thaiv corrosion zoo: Vinyl amine hmoov tuaj yeem tsim cov yeeb yaj kiab tiv thaiv, uas tuaj yeem tiv thaiv cov ntaub ntawv hlau los ntawm corrosion thiab oxidation thiab ua rau lawv lub neej ntev.
High hnav tsis kam: ntxiv vinblastine hmoov rau txheej txheej tuaj yeem ua rau cov tawv tawv thiab hnav tsis kam ntawm txheej thiab tiv thaiv cov khoom coated los ntawm khawb thiab hnav.
Txo cov emission ntawm volatile organic tebchaw (VOC): Vinyl amine hmoov tuaj yeem siv los ua cov khoom siv los hloov cov kuab tshuaj, uas txo cov ntsiab lus ntawm volatile organic tebchaw nyob rau hauv cov coatings thiab yog ib puag ncig zoo.

Cov yam ntxwv ntawm vinblastine hmoov

Cov huab cua zoo: Vinyl amine hmoov tuaj yeem tiv taus ultraviolet rays, oxidation, corrosion thiab tshuaj yaig, thiab khaws cov xim thiab luster ntawm txheej rau lub sijhawm ntev.
High abrasion tsis kam: cov txheej ntxiv nrog vinblastine hmoov muaj qhov zoo heev hardness thiab abrasion tsis kam, uas tuaj yeem tiv thaiv qhov chaw ntawm cov khoom coated los ntawm khawb thiab puas.
Corrosion kuj: Vinyl amine hmoov tuaj yeem tsim cov yeeb yaj kiab tiv thaiv, uas tuaj yeem tiv thaiv cov ntaub ntawv hlau los ntawm corrosion thiab oxidation.
Kev ruaj ntseg tshuaj zoo heev: Vinyl amine hmoov muaj zog tiv thaiv cov tshuaj, yog li cov txheej txheem tseem tuaj yeem tswj tau qhov kev ua tau zoo nyob rau hauv ib puag ncig ntawm cov tshuaj corrosion.
Emission ntawm tsawg volatile organic tebchaw (VOC): Siv vinblastine hmoov li pigment yuav txo tau VOC cov ntsiab lus nyob rau hauv cov xim, uas yog ib puag ncig tus phooj ywg.

Yuav tiv tauj peb li cas?

Peb lub tuam txhab yog cov kws tshaj lij ntawm cov khoom siv raw khoom ib nrab, suav nrog cov nroj tsuag extract, txiv hmab txiv ntoo thiab zaub hmoov, tshuaj pleev ib ce, ntsiav tshuaj khoom qab zib thiab lwm yam khoom; Peb cov khoom tau muab ncaj qha los ntawm cov chaw tsim khoom, yog li tus nqi yog qhov zoo heev, thiab qhov zoo yog lav, yog li koj tuaj yeem so assured mus yuav. Hnub no, peb muagVincamine hmoov,ib tug premium additive rau kev kho mob, tshuaj, kev tu tawv nqaij thiab lwm yam khoom.

Yog tias koj txaus siab rau cov khoom no thiab xav paub ntau ntxiv txog nws, koj tuaj yeem sab laj nrog peb tus thawj tswj hwm tus account los ntawm thoob ntiaj teb lub vev xaib lossis email, peb tus email chaw nyob yogella.zhang@huilinbio-tech.com ib; Peb lub Hoobkas nyob hauv Chav 706, Tsev B, Fengze Science Park, No.170 West Street, Yanta District, Xi 'an City, Shaanxi Province.