Raws li cov pej xeem thoob ntiaj teb muaj hnub nyoog, kev tswj hwm kev txawj ntse tau dhau los ua qhov tseem ceeb ntawm kev noj qab haus huv rau pej xeem. Ib txoj kev tshawb fawb tshiab tshaj tawm los ntawm Nyij Pooj, tshwm sim hauvFrontiers nyob rau hauv Khoom noj khoom haus, tshaj tawm tias kev noj txhua hnub ntawm cuminaldehyde-nplua nuj cumin tseem ceeb roj (CEO) tuaj yeem txhim kho ob qhov tshwj xeeb ntawm kev txawj ntse hauv cov neeg laus noj qab haus huv: psychomotor ceev thiab lub sijhawm tshuaj tiv thaiv.
12-lub lim tiam randomized, ob-dig muag, placebo-tswj mus sib hais koom nrog 38 noj qab nyob zoo Nyiv cov neeg koom nrog hnub nyoog 65 txog 86. Cov neeg nyob hauv pawg CEO tau noj ib koob tshuaj txhua hnub muab 25 mg ntawm cuminaldehyde-cov khoom tseem ceeb bioactive ntawm cumin tseem ceeb roj-thaum cov placebo pab pawg neeg tsis muaj roj active-look. Kev paub txog kev ua tau zoo tau raug ntsuas los ntawm kev siv Cognitrax kuaj roj teeb ua ntej thiab tom qab kev cuam tshuam.
Cov ntsiab lus tseem ceeb: Kev txhim kho hauv kev nrawm thiab kev teb
Cov txiaj ntsig tau pom tias pawg CEO tau ntsib ib qho8% kev txhim kho hauv psychomotor ceevthiab a10% txo qis hauv cov tshuaj tiv thaiv lub sijhawmpiv rau cov hauv paus, nrog rau ob qho kev hloov pauv mus txog qhov tseem ceeb ntawm cov ntaub ntawv txheeb ze rau cov placebo.
"Psychomotor qeeb qeeb yog ib qho tseem ceeb ntawm kev laus ib txwm muaj thiab tseem ceeb ntawm dementia," cov kws tshawb fawb tau piav qhia. "Tsis tas li ntawd, psychomotor ceev yog ib qho tseem ceeb rau ntau yam kev ua ub no txhua hnub, xws li txo qis kev pheej hmoo poob, tsav tsheb, ua si suab paj nruag, thiab ua lwm yam haujlwm zoo. Muab nws qhov tseem ceeb hauv lub neej niaj hnub, kev tswj xyuas psychomotor ceev yog qhov tseem ceeb rau cov neeg laus."
Cov kev txhim kho pom tau hais tias CEO supplementation tuaj yeem txhim kho kev ua haujlwm ntawm neurocognitive thiab zoo lub cev muaj zog hauv cov neeg laus, qhia txog nws lub peev xwm los pab txhawb kev paub txog kev noj qab haus huv thiab kev ywj pheej ntawm cov neeg laus.
Tsis muaj kev txhim kho hauv kev nco, kev ua haujlwm, lossis kev saib xyuas
Cov kws tshawb fawb tau sau tseg tias tsis muaj kev txhim kho tseem ceeb hauv kev tshawb fawb txog kev nco, kev ua haujlwm ceev, kev ua haujlwm, lossis kev saib xyuas. Cov txiaj ntsig kev txawj ntse tau tshwj xeeb tshwj xeeb rau kev ceev psychomotor thiab lub sij hawm tshuaj tiv thaiv -ob qho tib si txuas nrog lub peev xwm ua haujlwm txhua hnub.
Muaj peev xwm mechanisms: anti-inflammatory thiab neuroprotective txoj kev
Txoj kev tshawb no cov kws sau ntawv taw qhia txog cov pov thawj uas twb muaj lawm qhia tias cuminaldehyde-nplua nuj cumin tseem ceeb roj tuaj yeem txo cov qib pro-inflammatory cov cim xws li TNF-alpha thiab IL-6, nrog rau kev hloov pauv cov kev qhia ntawm cov noob txuas rau BDNF (lub hlwb-derived neurotrophic factor)-lub luag hauj lwm hauv kev tiv thaiv kab mob neuronde, kev loj hlob thiab kev loj hlob.
Kev tshawb nrhiav biomarker kev soj ntsuam hauv kev sim pom tias IL-6 qib tau txo qis hauv pawg CEO ntau dua li hauv pawg placebo, txawm hais tias tsis muaj kev cuam tshuam loj ntawm pawg los ntawm lub sijhawm raug kuaj pom rau ib qho biomarker, qhia tias yuav tsum muaj kev tshawb fawb ntxiv los tsim txoj hauv kev.
Kawm cov kev txwv
Cov kws tshawb fawb tau ceeb toom tias qhov no yog qhov kev sim sim nrog tus qauv me me (38 tus neeg koom) thiab tias txhua tus neeg koom nrog noj qab haus huv Nyij Pooj cov neeg laus, uas tuaj yeem txwv tsis pub muaj txiaj ntsig rau lwm tus neeg. Qhov tsis muaj kev hloov pauv tseem ceeb ntawm biomarker kuj qhia tau tias cov txheej txheem hauv qab ntawm kev pom kev txhim kho kev txawj ntse tseem yuav tsum tau piav qhia tag nrho. Cov kev tshawb fawb loj dua, ntev ntev yuav tsum tau ua kom paub tseeb tias cov kev tshawb pom no thiab txiav txim siab txog kev noj tshuaj kom zoo.
Nyiaj txiag thiab nthuav tawm
Txoj kev tshawb no tau nyiaj los ntawm S&B Foods Inc. thiab Japan Science thiab Technology Agency.
Takeaway
Rau cov neeg tsim khoom ntxiv rau lub hom phiaj ntawm kev noj qab haus huv cov neeg laus, txoj kev tshawb fawb taw qhia rau lub luag haujlwm muaj peev xwm rau cuminaldehyde-standardised cumin tseem ceeb roj hauv cov khoom lag luam tsom rau kev txhawb nqa psychomotor muaj nuj nqi thiab cov tshuaj tiv thaiv ceev- cov thawj coj ncaj qha rau kev tiv thaiv kev poob thiab kev ywj pheej txhua hnub hauv cov neeg laus.
Kev siv
Tseem ceeb Disclaimer
Cov ntaub ntawv muaj nyob rau hauv tsab xov xwm no yog rau kev kawm thiab cov ntaub ntawv lub hom phiaj nkaus xwb thiab tsis yog npaj raws li cov lus qhia kho mob. Nws tsis hloov kev sab laj kev kho mob, kev kuaj mob, lossis kev kho mob. Nco ntsoov nrhiav cov lus qhia ntawm tus kws kho mob uas tsim nyog nrog rau cov lus nug uas koj muaj txog kev mob nkeeg lossis ua ntej pib cov txheej txheem ntxiv tshiab. Cov khoom thiab cov khoom xyaw uas tau hais los no tsis yog tsim los kuaj, kho, kho, lossis tiv thaiv kab mob.
🧠 Cov khoom lag luam ntsig txog - Cov khoom xyaw rau kev paub txog kev noj qab haus huv
Thaum cov ntaub ntawv pov thawj kho mob saum toj no yog tshwj xeeb rau cuminaldehyde-nplua nuj cumin tseem ceeb roj, cov khoom xyaw hauv qab no los ntawm peb cov khoom sau tau kawm txog lawv lub peev xwm los txhawb kev txawj ntse, kev xav ceev, thiab tag nrho lub hlwb kev noj qab haus huv hauv cov neeg laus.
Cov ntaub ntawv muaj nyob rau hauv tsab xov xwm no yog rau kev kawm thiab cov ntaub ntawv lub hom phiaj nkaus xwb thiab tsis yog npaj raws li cov lus qhia kho mob. Nws tsis hloov kev sab laj kev kho mob, kev kuaj mob, lossis kev kho mob. Nco ntsoov nrhiav cov lus qhia ntawm tus kws kho mob uas tsim nyog nrog rau cov lus nug uas koj muaj txog kev mob nkeeg lossis ua ntej pib cov txheej txheem ntxiv tshiab.
Cov khoom thiab cov khoom xyaw uas tau hais los no tsis yog tsim los kuaj, kho, kho, lossis tiv thaiv kab mob.