Kev piav qhia
Vitamin D yog qhov tseem ceeb rau cov pob txha noj qab haus huv, kev tiv thaiv kab mob, thiab kev noj qab haus huv tag nrho[1]. Lub cev muaj peev xwm tsim tau los ntawm tshav ntuj, tab sis ntau tus neeg tsis tau txais kev tshav ntuj txaus - ua cov tshuaj ntxiv thiab cov khoom noj uas tsim nyog. Vitamin D2 (ergocalciferol) yog ib qho ntawm ob hom tseem ceeb ntawm vitamin D. Nws yog tsim los ntawm ergosterol, ib tug compound pom nyob rau hauv fungi, poov xab, thiab nroj tsuag, los ntawm UV irradiation.[2]. Qhov no ua rau nws yog ib qho ntshiab, cog los ntawm cov vitamin D.
Xav txog cov vitamin D2 ua "pro-hormone" uas lub cev hloov mus rau hauv nws cov active daim ntawv nyob rau hauv ob kauj ruam: thawj nyob rau hauv daim siab, ces nyob rau hauv lub raum.[3]. Thaum ua haujlwm, nws pab lub cev nqus calcium thiab phosphorus, txhawb cov pob txha muaj zog, thiab txhawb kev tiv thaiv kab mob.[4]. Rau cov neeg siv khoom nrhiav vegan-phooj ywg, tsis yog tsiaj los ntawm vitamin D, ergocalciferol yog qhov kev xaiv zoo tshaj plaws. Nws feem ntau lees paub tias muaj kev nyab xeeb (GRAS) los ntawm FDA thiab ua raws li USP, EP, thiab FCC cov lus qhia thoob ntiaj teb.
Physicochemical Properties & Specifications
| Khoom | Tus nqi |
|---|---|
| CAS Nr | 50-14-6 |
| Molecular Formula | C₂₈H₄₄O |
| Molecular Luj | 396.65 - 396.70 g / mol |
| Qhov tshwm sim | Dawb rau tawm -dawb crystalline hmoov |
| tsw / Saj | Tsis hnov tsw, tsw |
| Melting Point | 111.0-118.0℃(decomposes) |
| Solubility hauv dej | Insoluble |
| Solubility hauv Organic Solvents | Soluble hauv ethanol, methanol, acetone, chloroform, diethyl ether, DMSO |
| Solubility nyob rau hauv zaub roj | Me ntsis soluble |
| Specific Optical Rotation | +102℃rau +107℃(hauv ethanol) |
| Poob rau ziab | Tsawg dua lossis sib npaug li 0.5% |
| Assay Purity | 97.0–103.0% (USP / EP specifications, raws li qhuav) |
| Cia Kub | 2-8℃(tub yees) |
| Kev cia khoom | Hermetically kaw ntim hauv qab nitrogen, tiv thaiv los ntawm lub teeb |
| Txee lub neej | 48 lub hlis raws li pom zoo cia |
| GHS Hazard Classification | GHS07 (tej zaum yuav ua rau tawv nqaij / qhov muag khaus nyob rau hauv daim ntawv concentrated) |
Mechanism ntawm Action
Vitamin D2 ua haujlwm zoo li atus yuam sijuas qhib koj lub cev muaj peev xwm siv calcium thiab phosphorus. Nov yog qhov nws tshwm sim hauv tsib kauj ruam.
Kauj Ruam 1 – Absorption
Vitamin D2 los ntawm cov khoom noj los yog cov tshuaj yog absorbed nyob rau hauv cov hnyuv me nrog kev pab los ntawm cov zaub mov muaj roj. Vim tias vitamin D yog fat-soluble, lub cev tuaj yeem khaws cia rau hauv cov ntaub so ntswg rog rau kev siv tom qab.
Kauj Ruam 2 – Ua kom lub siab (Storage Form)
Vitamin D2 mus rau lubdaim siab, qhov twg ib qho enzyme ntxiv ib pawg hydroxyl (–OH), tsim25-hydroxyvitamin D(calcidiol)[2][6]. Qhov no yog daim ntawv tseem ceeb ntawm cov vitamin D thiab cov kws kho mob ntsuas hauv kev kuaj ntshav.
Kauj Ruam 3 - Lub raum Ua Haujlwm (Active Hormone)
25-hydroxyvitamin D ces mus rau qhovlub raum, qhov twg thib ob enzyme ntxiv lwm pab pawg hydroxyl los tsim1,25-dihydroxyvitamin D(calcitriol)[2]. Qhov no yog tag nrho active, hormonal daim ntawv ntawm vitamin D.
Kauj ruam 4 – Cellular Action (Tus Tswv Hloov)
Active vitamin D taug kev los ntawm cov hlab ntsha thiab khi rau covVitamin D Receptor (VDR)nyob rau hauv cov hlwb ntawm txoj hnyuv, pob txha, ob lub raum, thiab lub cev tiv thaiv kab mob[1][7]. Qhov kev khi no hloov cov noob tshwj xeeb rau lossis tawm, tswj kev nqus calcium, pob txha pob txha, thiab kev tiv thaiv kab mob.
Kauj Ruam 5 - Kev tawg thiab tshem tawm
Ib qho enzyme hu uaCYP24A1rhuav tshem cov vitamin D molecules siv kom lawv tsis txhob tsim kom muaj tshuaj lom[2]. Qhov no yog lub cev lub ntuj tsim "cov neeg ua haujlwm huv."
Nyob rau hauv ib tug nutshell:
| Kauj ruam | Qhov chaw | Yuav ua li cas |
|---|---|---|
| 1 | Cov hnyuv me | Vitamin D2 yog absorbed |
| 2 | Daim siab | Hloov mus rau 25 (OH)D (storage form) |
| 3 | Lub raum | Hloov mus rau 1,25 (OH)₂D (ua haujlwm daim ntawv) |
| 4 | Cell nucleus (ntawm VDR) | Tig cov noob rau / tawm los tswj cov calcium, pob txha, thiab kev tiv thaiv |
| 5 | Ntau cov ntaub so ntswg | Siv cov vitamin D puas lawm |
Yog li thaum koj noj cov vitamin D2, koj tau muab koj lub cev ua kom cov pob txha muaj zog, lub cev tsis muaj zog, thiab kev ua haujlwm ntawm tes.[1][4][7].
Cov txiaj ntsig kev noj qab haus huv
1 Tsim thiab tswj cov pob txha muaj zog
Vitamin D pab lub cev nqus calcium, tiv thaiv rickets hauv cov menyuam yaus thiab osteomalacia hauv cov laus[3]. A 2026 meta-analysis tau lees paub tias vitamin D2 nce cov calcium hauv cov ntshav thiab txo PTH, pab tswj cov pob txha, tshwj xeeb tshaj yog cov laus.[5].
2 Txhawb kev tiv thaiv kab mob
Vitamin D receptors muaj nyob rau ntawm lub cev tiv thaiv kab mob, tso cai rau cov vitamin D los txhim kho cov kab mob-tiv thaiv cov lus teb thaum txo cov teeb meem o.[1]. Vitamin D ntxiv tau pom tias tiv thaiv kab mob ua pa nyuaj[4].
3 Tswj Calcium thiab Parathyroid Hormone (PTH)
Cov vitamin D tsawg ua rau PTH siab, uas rub cov calcium los ntawm cov pob txha. Vitamin D2 supplementation txo qis PTH qib, ua kom cov tshuaj no hauv kev kuaj xyuas[5].
4 Txhawb lub plawv thiab Metabolic Health
Vitamin D receptors muaj nyob rau hauv lub plawv cov leeg thiab cov hlab ntsha, qhia ncaj qha rau cov hlab plawv[1]. Txaus vitamin D kuj txhawb kev noj qab haus huv cov ntshav qab zib metabolism[3].
5 Txo qhov mob
Active vitamin D cuam tshuam rau kev tsim cov inflammatory tebchaw, pab tswj lub cev tiv thaiv kab mob sib npaug es tsis yog mob ntev.[1][4].
6 Txhawb kev xeeb tub
Vitamin D yog qhov tseem ceeb rau kev loj hlob ntawm cov pob txha hauv plab thiab kev tiv thaiv kab mob. Cov theem niam txaus yog cuam tshuam nrog kev noj qab haus huv ntawm cev xeeb tub, uas yog vim li cas ntau cov tshuaj ua ntej yug menyuam suav nrog vitamin D.[3].
Daim ntawv thov
1 Cov Khoom Noj Khoom Haus
Vitamin D2 hmoov yog siv nyob rau hauv multivitamins, standalone D2 tshuaj (400-50,000 IU), kua tee, gummy vitamins, sublingual sprays, thiab ua ke cov qauv nrog calcium los yog vitamin K2. Nws yog qhov kev xaiv zoo tshaj plaws rau cov vegan thiab cov nroj tsuag tshuaj ntxiv.
2 Khoom noj khoom haus thiab dej haus ua haujlwm
Feem ntau siv cov mis nyuj uas muaj roj (soy, almond, oat), noj tshais cereals, khoom noj siv mis, khoom noj khoom haus, kua txiv kab ntxwv, mis mos, margarine, thiab khoom ci. Vitamin D2 ruaj khov thiab ua haujlwm zoo hauv cov ntawv thov no.
3 Pharmaceutical Formulations
Siv raws li API nyob rau hauv cov tshuaj ntsiav tshuaj ntau npaum li cas (50,000 IU), txhaj tshuaj intramuscular, ntsiav tshuaj ntawm qhov ncauj, thiab cov tshuaj sib xyaw ua ke rau kev kho cov vitamin D tsis txaus, hypoparathyroidism, rickets, thiab hypophosphatemia.
4 Tsiaj Pub thiab Tsiaj Noj Tsiaj
Ntxiv rau cov nqaij qaib, swine, nyuj, thiab aquaculture pub rau cov pob txha noj qab haus huv thiab kev nqus calcium. Kuj tseem siv tau rau hauv cov zaub mov tsiaj, tshwj xeeb tshaj yog cov tshuaj cog qoob loo.
5 Cell Culture thiab Biotechnology Research
Ua hauj lwm hauv cov tsiaj ntawv xov xwm kab lis kev cai xov xwm, VDR kev tshawb fawb losis tswvyim dabtsi, kev tshawb fawb txog kev tiv thaiv kab mob, thiab fermentation media.
Cov lus nug nquag nug (FAQ)
Q: Yuav ua li cas ruaj khov vitamin D2, thiab yuav tiv thaiv li cas?
A: Vitamin D2 rhiab heev rau lub teeb, cua, cua sov, thiab noo noo. Txhawm rau kom muaj kev ruaj ntseg zoo tshaj plaws: siv cov ntim ntim UV-thaiv (lub khob amber iav, cov hnab ntawv ci), ntxiv cov tshuaj antioxidants (tocopherols), khaws cia ntawm 2-8 degree, tsis txhob muaj cua sov los yog shear processing, thiab xav txog microencapsulation. Tsim kom raug, nws khaws cia muaj zog txog li 48 lub hlis.
Q: Cov khoom no puas ua raws li kev cai thoob ntiaj teb?
A: Yog. Tsim nyob rau hauv GMP-certified chaw thiab ua raws li US (21 CFR §172.379), EU (EC 1925/2006, 2002/46/EC), Tuam Tshoj (GB 14880-2012), thiab JECFA cov qauv.
Q: Cov kev xaiv ntim khoom twg muaj?
A: Aluminium ntawv ci hnab (1-5 kg), ntim yas nruas (10-25 kg), fiber ntau nruas (25-50 kg), thiab customized ntim raws li kev thov. Tag nrho cov ntim yog lub teeb-tiv thaiv thiab hermetically kaw.
Q: Koj lub sijhawm ua haujlwm rau kev txiav txim ntau yog dab tsi?
A: Rau cov qauv txiav txim ntau (Ntau dua lossis sib npaug rau 25 kg), lub sijhawm ua haujlwm feem ntau yog 10-15 hnub ua haujlwm tom qab kev txiav txim pom zoo thiab them nyiaj.
Q: Koj puas muab cov kev cai formulations los yog encapsulation kev pab cuam?
A: Peb muab kev cai micronization, microencapsulation (los txhim kho kev ruaj ntseg thiab txee lub neej), kev cai premixes nrog lwm cov vitamins thiab minerals, thiab tshuaj tsuag-qhuav formulations. Thov hu rau peb pab neeg technical los tham txog koj cov kev xav tau tshwj xeeb.
Vim li cas thiaj xaiv peb?
Koj tus kws tshaj lij kev tsim khoom & Sourcing tus khub
Peb yog ntau tshaj li tus neeg muag khoom - peb yog cov khoom lag luam sib txuas ua ke rau siab - cov khoom xyaw zoo, cov qauv kev cai, thiab cov khoom tiav thoob plaws ntau qhov kev lag luam.
Cov kws tshaj lij
Nrog rau ntau xyoo ntawm kev paub hauv cov nroj tsuag extracts, khoom noj khoom haus additives, cosmetic raw cov ntaub ntawv, thiab cov khoom noj khoom haus, peb pab neeg coj cov kev txawj ntse txawj ntse thiab kev ua lag luam kev pom zoo rau txhua qhov kev koom tes.
01
Ntau Yam Khoom Muag
Peb muab ntau yam khoom lag luam, suav nrog cov khoom noj khoom haus ntxiv, cov nroj tsuag rho tawm, txiv hmab txiv ntoo & zaub hmoov, cov khoom siv tshuaj pleev ib ce, thiab cov khoom xyaw ua zaub mov.
02
Ib -Stop Shop
Raw Khoom:High -cov khoom xyaw purity rau zaub mov, dej haus, ntxiv, thiab kev siv tshuaj pleev ib ce.
Cov khoom tiav:Hauv -tsev tsim cov tshuaj ntsiav, mos gels, gummies, kua tee, thiab hmoov sib tov.
03
Kev pabcuam OEM / ODM / OBM
Label Design & Ntim:Kev cai branding tailored rau koj lub hom phiaj ua lag luam.
Formulation & R & D:Cov kws tshaj lij kev txhawb nqa los tsim cov kev cai sib xyaw, cov qauv tsim muaj, thiab cov khoom tsim tshiab.
Ntiaj teb no Logistics:Txhim khu kev xa khoom, cov ntaub ntawv, thiab kev pabcuam kev lis kev cai.
04
Quality Assurance
nruj me ntsis ua raws li GMP cov qauv thiab tag nrho cov kev cai pob tshab. Peb nyob twj ywm tam sim no nrog cov kev cai thoob ntiaj teb, suav nrog FDA GRAS, EFSA, thiab lwm yam kev cai hauv cheeb tsam, kom ntseeg tau tias koj cov khoom ua tau raws li cov qauv kev nyab xeeb siab tshaj plaws thiab ua raws.
05
Ua tam sim no
Npaj los tsim nrog hwm Pure Vitamin D2 Powder?
- Thov ib daim ntawv los yog qauv
- Thov Cov Ntaub Ntawv: COA, TDS, SDS, lossis cov ntaub ntawv ua raws cai
- Kev txiav txim ntau & Daim ntawv cog lus Manufacturing: Nug txog cov nqi luv nqi, daim ntawv cog lus mus sij hawm ntev, thiab kev tsim khoom ntiag tug.
- Txoj Cai Tswjfwm: Cov qauv kuaj ntsuas (10–100g) muaj rau kev tsim kho, kuaj kev ruaj ntseg, thiab kev soj ntsuam zoo.
Thov hu rau peb ntawmella.zhang@huilinbio-tech.com.
Cov ntaub ntawv
Cim npe nrov: vitamin d2 hmoov (ergocalciferol), Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, ntuj, zoo, Tshuag, kev muag
