Khoom Taw Qhia:
Potassium 4-methoxysalicylate tseem tuaj yeem hu ua 4-Methoxy Salicylic Acid KCI, abbreviated li 4MSK, uas yog cov hmoov dawb dawb crystalline hmoov nrog cov mis molecular ntawm C8H7KO4. Cov txiaj ntsig tseem ceeb ntawm cov khoom no yog ua kom tsis muaj teeb meem thiab sib tshooj ntawm stratum corneum vim UV raug, ua rau muaj qhov tsaus nti thiab freckles tshwm sim los ntawm kev mob tsis zoo keratinization. Nws muaj cov nyhuv ntawm kev txhim kho keratinization txawv txav thiab tuaj yeem thaiv qhov chaw ntawm melanin ntau lawm. Nws muaj peev xwm inhibit zus tau tej cov melanin thiab tiv thaiv qhov tshwm sim ntawm tsaus me ntsis thiab freckles, yog li nws yog dav siv nyob rau hauv lub teb ntawm tshuaj pleev ib ce.
Muaj nuj nqi:
Potassium 4-methoxysalicylate yog cov tshuaj pleev xim dawb, uas muaj cov teebmeem ntawm inhibiting zus tau tej cov melanin thiab tiv thaiv tej pob thiab freckles los ntawm lub hnub raug. 4MSK tsis tsuas yog muaj cov nyhuv ntawm inhibiting melanin ntau lawm tab sis kuj tuaj yeem kho qhov xwm txheej uas cov txheej txheem keratinization tsis du. 4MSK tuaj yeem rov qab tau tus lej ntawm cov khoom hauv qhov raug puas tsuaj, ua rau txhua theem ntawm cov yam ntxwv ua lub luag haujlwm hauv cov txheej txheem ntawm melanin excretion, teeb lub teeb pom kev ntawm melanin excretion, thiab ua rau melanin tsis poob nws cov kev taw qhia.
Whitening nyhuv ntawm poov tshuaj 4-methoxysalicylate:
Nyob rau hauv tus txheej txheem ntawm kev tshawb nrhiav tshiab whitening active cov khoom xyaw,4 MSKnrog cov nyhuv ntawm inhibiting melanin ntau lawm tau pom. Vim tias cov qauv ntawm 4MSK zoo ib yam li salicylic acid, thaum soj ntsuam cov nyhuv inhibitory ntawm melanin ntau lawm, Cov teebmeem ntawm 4MSK ntawm keratinocytes kuj tau kawm. Cov txiaj ntsig tau pom tias 4MSK tuaj yeem kho qhov tsis txaus ntawm keratinocytes qhov sib txawv. Ob qhov cuam tshuam ntawm cov kev sim hauv vitro tau pom tias 4MSK yuav muaj kev tiv thaiv lub zog ntawm kev tsim khoom thiab tso tawm ntau tshaj melanin uas ua rau melanin deposition ntawm daim tawv nqaij. Tsis tas li ntawd, nws tau kawm los ntawm kev sim hauv vivo tias 4MSK kuj muaj kev tiv thaiv zoo heev ntawm pigmentation los ntawm ultraviolet rays. Cov saum toj no hauv vitro thiab hauv vivo kev sim cov txiaj ntsig tau pom qhov ua tau ntawm 4 MSK los txhim kho pigmentation thiab freckles.
4MSK yog cov khoom siv ua kom dawb huv, uas tuaj yeem cuam tshuam kev tsim cov melanin, txo qhov pom ntawm pob thiab freckles, thiab ua rau daim tawv nqaij ci dua thiab translucent. Lub hauv paus ntsiab lus whitening ntawm 4MSK yog los txo qhov tsim ntawm melanin los ntawm inhibiting qhov kev ua ntawm tyrosinase. Melanin yog ib hom xim ntawm daim tawv nqaij, thiab nws tsim muaj feem xyuam rau ultraviolet hluav taws xob, oxidative kev nyuaj siab, thiab lwm yam. Melanin ntau dhau yuav ua rau tawv nqaij du, pigmentation, thiab lwm yam teeb meem. 4MSK tuaj yeem cuam tshuam kev tsim cov melanin, yog li txhim kho cov xim ntawm daim tawv nqaij. Ntxiv nrog rau cov nyhuv whitening, 4MSK kuj muaj cov nyhuv antioxidant, uas tuaj yeem tiv thaiv dawb radicals thiab tiv thaiv kev laus ntawm daim tawv nqaij.
Tsis tas li ntawd, 4MSK tseem tuaj yeem txhawb cov tawv nqaij metabolism, txhim kho daim tawv nqaij muaj peev xwm moisturizing, thiab ua kom tawv nqaij noj qab haus huv thiab yau dua. Feem ntau hais lus, 4MSK yog cov khoom ua kom dawb nrog ntau lub zog, uas tuaj yeem txhim kho cov xim ntawm daim tawv nqaij, oxidation tsis kam, noo noo, thiab lwm yam. Nws yog ib qho ntawm feem ntau siv cov khoom xyaw whitening hauv tshuaj pleev ib ce.
Nws yog ib qho tsim nyog sau cia tias thaum siv cov tshuaj pleev ib ce uas muaj 4MSK, peb yuav tsum tau xyuam xim tiv thaiv daim tawv nqaij, tsis txhob siv hluav taws xob ultraviolet, thiab tsis txhob siv ntau dhau, kom tsis txhob ua rau tawv nqaij.
Kev ua tau zoo ntawm potassium 4-methoxysalicylate hauv tshuaj pleev ib ce:
Kev ua tau zoo hauv cov tshuaj pleev ib ce thiab cov khoom siv tshuaj niaj hnub yog feem ntau ua kom tawv nqaij, ua kom pom kev, tshem tawm pob, thiab tshem tawm cov voj voog tsaus. 4MSK tuaj yeem kho qhov tsis sib xws ntawm keratinocyte sib txawv. 4MSK tsis tsuas yog muaj cov nyhuv tib yam ntawm inhibiting melanin ntau lawm raws li cov khoom xyaw ua kom dawb huv uas twb muaj lawm tab sis kuj muaj cov txiaj ntsig ntawm kev tswj hwm keratinocyte sib txawv, uas tuaj yeem txhim kho daim tawv nqaij lub xeev qhov twg melanin yooj yim tso nyiaj ntau dhau. 4MSK kuj tseem tuaj yeem txhim kho cov pob qij txha thiab freckles, thiab nws tuaj yeem siv los ua cov khoom ua kom zoo nkauj zoo nkauj. Raws li ib tug derivative ntawm salicylic acid, salicylic acid yog ib tug ntawm cov tseem ceeb Cheebtsam nyob rau hauv lub synthesis ntawm aspirin. Cov kev sim tau ua pov thawj tias "qhov ncauj" salicylic acid muaj qhov cuam tshuam zoo sib xws rau qhov ncauj tshuaj aspirin, uas tuaj yeem ua rau fetal malformation, thiab ua rau muaj kev pheej hmoo ntawm nchuav menyuam thiab lwm yam teeb meem ntawm cev xeeb tub. Ntawm qhov tod tes, tsis muaj kev sim ua pov thawj tias "siv sab nraud" ntawm salicylic acid yuav muaj kev cuam tshuam rau cov poj niam cev xeeb tub. Rau kev nyab xeeb, nws raug pom zoo tias cov poj niam cev xeeb tub thiab lub sijhawm lactation siv cov khoom uas muaj cov khoom no ceev faj.
Potassium 4-methoxysalicylate, zoo ib yam li hauv cov qauv rau salicylic acid, yog ib qho tshuaj dawb huv tshiab, uas yog siv rau cov tshuaj pleev ib ce thiab ua lub luag haujlwm kom dawb. Nws muaj lub luag haujlwm ntawm kev txhim kho cov xim ntawm daim tawv nqaij, txo cov pigmentation ntau dhau, kho atypical proliferation ntawm epidermis, txhawb melanin tawm, thiab tiv thaiv freckles thiab me ntsis, yog li tsim cov tawv nqaij du. Nws cov haujlwm tshwj xeeb yog:
1. Melanin metabolism
Hauv daim ntawv tshaj tawm kev tshawb fawb, nws tau pom tias cov qauv ntawm daim tawv nqaij nrog 4MSK tau irradiated los ntawm ultraviolet rays, uas cuam tshuam qhov txo qis ntawm kev nthuav qhia ntawm lub hnab protein los ntawm ultraviolet rays. Raws li cov qauv kev sim hauv vitro, 4MSK thiab salicylic acid muaj qee yam zoo sib xws hauv kev ua haujlwm, uas tuaj yeem txhawb cov metabolism ntawm melanin.
2. Lnhibit zus tau tej cov melanin
Tus yuam sij rau kev kawm cov khoom xyaw whitening yog los tshuaj xyuas qhov tseeb ntawm melanin thiab inhibition ntawm tyrosinase. Hauv luv luv, 4MSK tuaj yeem cuam tshuam melanin ntau lawm thiab tyrosinase kev ua haujlwm nyob rau hauv ib puag ncig concentration. Qhov concentration dependence ntawm tus qub yog 310-4 thiab 10-3 mol / L, thiab tom kawg yog 510-4 ~ 310-3 mol / L.
3. PIH tiv thaiv nyhuv
Daim ntawv tshaj tawm qhia tau hais tias nyob rau hauv qee lub hnub ci, 1% ntawm 4MSK cov khoom muaj txiaj ntsig ntawm kev txo PIH, thiab qhov ntau qhov concentration nce, qhov tseem ceeb ntawm kev txo qis. Raws li cov khoom xyaw ua kom tawv nqaij, nws cov qib ntawm kev ua haujlwm tseem ua tau raws li kuv qhov yuav tsum tau ua, thiab nws muaj peb theem ntawm kev ua kom txo qis dullness ntawm daim tawv nqaij, uas yog cov khoom sib xyaw ua kom zoo nkauj.
Yuav tiv tauj peb li cas?
Peb yog ib lub tuam txhab nrog ntau xyoo ntawm kev muag khoom nyob rau hauv cov nroj tsuag extract kev lag luam. Tom qab xyoo ntawm kev ua haujlwm, peb muaj ntau yam khoom, xws li zaub hmoov, tshuaj pleev ib ce, ntsiav tshuaj khoom qab zib, thiab lwm yam khoom. Peb yog cov kws tshaj lij ntawm cov khoom siv raw khoom. Tam sim no, peb lub tuam txhab muag zoopoov tshuaj 4-methoxysalicylate, uas yog dav siv hauv cov khoom kho mob, tshuaj pleev ib ce, thiab lwm yam. Cov uas yuav tsum tau ua cov khoom noj qab haus huv tuaj yeem yuav cov khoom siv raw. Nyob rau tib lub sijhawm, peb cov khoom yog txhua lub Hoobkas ncaj qha muag, qhov zoo yog lav, thiab koj tuaj yeem yuav lawv nrog kev ntseeg siab. Cov neeg uas xav yuav lossis xav tau tuaj yeem mus rau peb lub thawv xa ntawv los ntawm thoob ntiaj teb lub vev xaib lossis e-mailella.zhang@huilinbio-tech.com ib.